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Tingling and numbness from low vitamin B12 | CION Cancer Clinics

Yes, a shortage of vitamin B12 can cause tingling, numbness and burning, usually starting in both feet, along with poor balance and memory changes. It can happen even when your haemoglobin is normal. These nerve symptoms need prompt attention, because nerves recover best when treatment starts early. Diabetes, thyroid problems and some medicines cause similar symptoms, so blood tests and an examination decide the cause. At CION Cancer Clinics, our haematologist cares for anaemia, bleeding, clotting and inherited blood disorders, with ArogyaSri, CGHS and cashless insurance accepted.

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Medically reviewed by Dr. Basudev PokhrelConsultant Haematologist · last reviewed September 2026, next review due September 2027
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The short answer

Can low B12 cause tingling and numbness?

Yes. A shortage of vitamin B12 can damage the nerves and cause pins and needles, numbness or burning, usually starting in both feet. Nerve symptoms from low B12 need prompt medical attention, because the longer they go on, the less likely they are to settle fully.

Why B12 matters to your nerves

Your nerves are wrapped in a protective coating, a little like the plastic around an electric wire. B12 helps the body build and repair that coating. When B12 runs short for a long time, the coating and the nerve inside it start to suffer, and messages between your feet, hands and brain get muddled.

It can happen with a normal blood count

Many people expect low B12 to show up first as a low haemoglobin. That is not always true. Nerve symptoms can appear while the blood count and the size of the red cells are still normal. So a normal blood report does not rule B12 out when you have tingling.

Not every tingle is B12

Diabetes is the most common cause of tingling feet in India. Thyroid problems, alcohol, some medicines and a trapped nerve in the neck or back can feel similar. The tests below help your doctor tell them apart.

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When this cannot wait

Go to the nearest emergency department or call 108 the same day if numbness or weakness comes on suddenly, affects one side of the face or body, or comes with slurred speech. These can be signs of a stroke, not B12. See a doctor within a day or two if you are losing your balance, falling, finding it hard to walk, or losing control of your bladder.

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Recognising it

What do B12 nerve symptoms feel like?

People describe them in different ways. Mention every one you have noticed, even the ones that seem unrelated.

In the feet and hands

Pins and needles, numbness, burning or a feeling of walking on cotton wool. It usually starts in both feet and can later reach the hands.

Often noticed as

  • Slippers falling off without you feeling it
  • Trouble doing up buttons

Balance and walking

Feeling unsteady, especially in the dark or with your eyes closed, such as while washing your face. Some people start holding the wall or the railing on the stairs.

Memory, mood and thinking

Forgetfulness, confusion, low mood or irritability. In older parents these changes are easy to put down to age.

A family member often notices these before the person does.

Other clues that go with it

A sore, smooth red tongue, mouth ulcers, tiredness, breathlessness on stairs or pale skin. These point towards low B12 but do not prove it.

Side by side

Is it B12 or something else?

Only tests can tell. These are general patterns, and you can have more than one cause at once.

Possible cause What usually points to it
Low B12 Vegetarian diet, metformin, acid tablets, stomach surgery, older age
Diabetes High sugar over years; burning feet, often worse at night
Thyroid problem Weight change, feeling cold, tiredness; picked up on a thyroid test
Trapped nerve in the neck or back Often one side, with neck or back pain
Alcohol or some medicines Regular drinking, or certain cancer and TB medicines

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The pathway

What happens from first tingling to treatment?

  1. You tell a doctor about the symptoms

    Say when the tingling started, where it is and whether your balance or memory has changed. Bring a list of every medicine, tonic and supplement you take.

  2. An examination

    The doctor checks feeling, reflexes, balance and walking. This shows how far the nerves are affected and gives a starting point to compare against later.

  3. Blood tests

    Usually B12, a full blood count, folate, sugar and thyroid. If the B12 result is borderline, a sharper test such as MMA or active B12 may be added.

  4. Treatment starts promptly

    When nerve symptoms are present, doctors usually do not wait long. Injections are commonly used at first. Your doctor sets the plan and the schedule.

  5. The cause is looked for

    Diet, medicines and absorption problems are checked, because the cause decides how long treatment may continue.

  6. Follow-up visits

    Nerves heal slowly. Your doctor rechecks your symptoms over the following months rather than relying on a blood number alone.

Commonly believed

What do families often get wrong about B12 and nerves?

"Tingling in old age is normal. Nothing can be done."

Tingling is common in older people, but it is not simply age. Low B12 is one cause that can often be treated, and finding it early gives the nerves the better chance of settling.

"A folic acid tablet will fix it, since it is the same thing."

Folic acid and B12 are different vitamins. Folic acid on its own can improve the blood count while nerve damage from low B12 goes on. Tell your doctor before taking folic acid if tingling is present.

"Once the injections start, the numbness goes in a few days."

Blood results often improve quickly. Nerves take much longer, and some long-standing numbness may not recover completely. Slow progress does not mean treatment is failing.

"My sugar is controlled, so the tingling cannot be from diabetes medicine."

Metformin, a common diabetes tablet, can lower B12 over years even when sugar is well controlled. Ask your doctor whether a B12 test is due. Do not stop metformin on your own.

Being straight with you

Will the nerves recover, and what can this page not tell you?

Many people notice their symptoms ease once treatment starts. How much they recover depends mostly on how long the nerves were short of B12 and how badly they were affected. Symptoms that are caught early tend to do better than those that have been present for a long time.

Who is more at risk

People on a strict vegetarian diet, older adults, people taking metformin or acid-reducing tablets for years, and anyone who has had stomach or bowel surgery. An autoimmune condition that stops the stomach absorbing B12 is another cause, and it runs in some families.

What this page cannot tell you

It cannot tell you whether your tingling comes from B12. A symptom list is not a diagnosis, and more than one cause can be present. It also cannot tell you how much your own nerves will recover. Your doctor can judge that after examining you and watching how you respond.

Please do not start, stop or change any medicine or injection because of this page. The treating team sets the plan.

Questions we are asked

Common questions about B12 and tingling

Can B12 deficiency cause tingling even if my haemoglobin is normal?

Yes. Nerve symptoms can appear before the blood count changes. A normal haemoglobin and normal-sized red cells do not rule out low B12 when you have tingling or numbness. Your doctor may still test B12 and, if the result is borderline, add a sharper test such as MMA.

How long does it take for tingling to improve after treatment?

It varies from person to person. Blood results usually improve first. Nerves repair slowly, so tingling may ease gradually over many months. Some long-standing numbness does not go away completely. Your doctor will follow your symptoms at each visit rather than judging by the blood test alone.

Are B12 tablets enough if I have nerve symptoms?

When nerve symptoms are present, doctors usually start with injections, because they bypass any absorption problem in the gut. Whether you can move to tablets later depends on the cause of the shortage. That decision belongs to your doctor. Do not switch or stop treatment on your own.

I have diabetes and take metformin. Could my tingling be B12?

It could be either, or both. Diabetes itself damages nerves, and long-term metformin can lower B12. A B12 test helps separate the two, because low B12 can be treated. Ask your doctor about testing. Keep taking metformin unless your doctor tells you otherwise.

Can low B12 affect memory in my elderly father?

It can. Low B12 can cause forgetfulness, confusion and mood changes, and these are easily mistaken for ageing. It is one of the causes a doctor checks when memory changes. Not every memory problem is B12, so a proper assessment is needed rather than simply starting supplements at home.

Which doctor should I see for B12 tingling?

Your family doctor or a general physician is a good start. A neurologist, a doctor for nerve problems, may be involved if the cause is unclear. A haematologist, a doctor for blood disorders, is often asked to review when the blood count is also abnormal or the cause of the shortage is uncertain.

Do I need a nerve test as well as a blood test?

Not always. Many people are diagnosed with a careful examination and blood tests. A nerve conduction study, which measures how fast signals travel along your nerves, may be suggested if the cause is unclear, symptoms are severe, or they do not improve as expected.

Can I just take a B12 supplement from the pharmacy?

It is better to be tested first. Supplements raise the blood level and can make a later test hard to read. If the cause is an absorption problem, a shop tablet may not be enough for damaged nerves. See a doctor, get tested, and follow the plan they set.

Your Haematologist

Meet CION's haematologist. One specialist for your blood report and your plan.

Dr. Basudev Pokhrel reviews blood counts, transfusion needs and blood disorders, and works with the CION tumour board on blood cancers.

Dr. Basudev Pokhrel
Hematologist

Dr. Basudev Pokhrel

MBBS, M.D (Immunohematology & Blood Transfusion)

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Where to find us

Our centres in and around Hyderabad

Addressed by landmark, because that is how this city navigates. A haematology consultation can be booked at any of these centres through one helpline, and your team will tell you where each test or treatment takes place.

CION Ameerpet

Beside Blue Fox Hotel, Satyam Theatre Road

Begumpet SR Nagar Punjagutta
CION Kukatpally

Opposite Big Bazaar, Mumbai Highway

KPHB JNTU Bharat Nagar
CION L.B. Nagar

Anu Arcade, next to L.B. Nagar Metro station

Vanasthalipuram Nagole Hayathnagar
CION Tolichowki

Inside Premier Hospital, Khader Bagh Road

Mehdipatnam Attapur Rethibowli
CION Masab Tank

Mahavir Hospital, AC Guards, Lakdikapul

Lakdikapul Khairatabad Basheer Bagh
CION Banjara Hills

Road No. 12

Jubilee Hills Madhapur Film Nagar
CION Kompally

Suchitra Circle, NH-44

Suchitra Circle Alwal Dundigal
CION Balanagar

Balanagar Main Road

Balanagar Fatehnagar Moosapet
CION Siddipet

Lohith Sai Hospital, Shivaji Nagar

Gajwel Husnabad Dubbaka
CION Sangareddy

X Roads, Pothreddipalle

Narayankhed Zaheerabad Patancheru

Sources

  1. NHS — Vitamin B12 or folate deficiency: symptoms
  2. National Health Mission — National Health Mission
  3. NICE — Vitamin B12 deficiency in over 16s: diagnosis and management (NG239)
  4. NHLBI — Vitamin B12 deficiency and low blood counts

This page is general information, not a prescription. Do not change or stop any treatment based on what you read here. If anything is worrying you, contact your own treating team — or call our helpline and we will help you reach the right specialist.

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