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Hyderabad's Multidisciplinary Oral Cancer Team

Oral Cancer — Types, Symptoms & When to See a Specialist

India accounts for nearly one in three oral cancers worldwide — and the burden is particularly heavy in Telangana and Andhra Pradesh, where gutkha, paan and tobacco chewing remain part of daily life. Most oral cancers are visible to the naked eye long before they spread, which means awareness, regular self-examination, and acting on a non-healing mouth ulcer can be genuinely life-saving.

  • Mostly Preventable — Almost all oral cancers in India are linked to tobacco, gutkha, areca-nut or alcohol — habits you can stop.
  • Highly Curable Early — Stage I & II cancers have 75–90% 5-year survival when surgery is timed right.
  • Visible to the Eye — Most oral cancers can be seen or felt during a 2-minute self-exam at home.
  • Tumor Board for Every Patient — Surgery, medical and radiation oncology together — no single-doctor decisions.
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What is Oral Cancer?

Oral cancer is a malignant growth that develops in any part of the mouth — the lips, tongue, inner cheek lining (buccal mucosa), gums, floor of the mouth, hard palate, or the area just behind the wisdom teeth. The vast majority of oral cancers are squamous cell carcinomas, which arise from the thin, flat cells lining the inside of the mouth.

Oral cancer is one of the most common cancers in India and the single most common cancer in Indian men. Almost all cases are linked to tobacco use — smoked or chewed — frequently combined with alcohol or betel-quid (paan). The good news is that the mouth is one of the few parts of the body you can examine yourself: in front of a mirror, every month, for two minutes. That simple habit, combined with prompt action on any ulcer that does not heal within 2 weeks, is the most effective early-detection tool we have.

Subtypes

Types of Oral Cancer

Oral cancers are usually grouped by the part of the mouth in which they begin. The type and location influence symptoms, treatment, and the impact on speech, swallowing and appearance.

Most common in India

Buccal Mucosa Cancer (Inner Cheek)

The most common type of oral cancer in India because gutkha, zarda and paan are usually held in the cheek for long periods. It often develops at the exact spot where the quid is kept and is preceded by a thick white patch (leukoplakia) or restricted mouth opening (oral submucous fibrosis).

Second most common

Tongue Cancer

Usually appears on the side of the tongue as a non-healing ulcer or a thickened patch. Tongue cancers can affect speech and swallowing, and require careful surgical planning to preserve function.

Visible early

Lip Cancer

Most commonly affects the lower lip, often linked to chronic sun exposure and smoking. Often diagnosed early because it is visible, with excellent cure rates with surgery.

Aggressive spread

Floor-of-Mouth, Gum & Palate Cancers

Less common but important subtypes. Floor-of-mouth cancers can spread quickly to lymph nodes in the neck. Gum and palate cancers often present as a persistent swelling, a non-healing socket after a tooth extraction, or unexplained loose teeth.

HPV link globally

Oropharyngeal Cancer (Throat)

Cancer in the back of the mouth and upper throat, including the tonsils and base of tongue. Globally these are increasingly linked to HPV infection; in India, tobacco and alcohol remain the dominant drivers.

For detailed information on diagnosis, surgical and reconstructive treatment options, see our dedicated page on oral cancer treatment in Hyderabad.

Did You Know?

Gutkha, paan-with-tobacco and areca-nut are the single biggest drivers of oral cancer in Telangana — and they affect women as well as men. Many women in the region who have never smoked use chewing tobacco daily, and account for a significant share of oral cancers presenting at advanced stages.

First signs of oral cancer

Common Signs & Symptoms of Oral Cancer

Most oral cancers are visible or can be felt during a self-examination. Watch for any of the following — especially if they persist for more than 2 weeks:

Non-healing ulcer — A mouth ulcer or sore that does not heal within 2 weeks.
White or red patch — Leukoplakia, erythroplakia, or a mixed red-and-white patch inside the mouth.
Thickened lump — A thickened area or lump inside the cheek, on the gum, or under the tongue.
Persistent pain or numbness — Pain, numbness, or tingling in the mouth, lip or tongue that won't go.
Restricted mouth opening — Difficulty opening the mouth wide or stiffness in the cheeks (key warning sign of OSMF).
Unexplained loose teeth — Or a tooth socket that does not heal after extraction.
One-sided ear pain — Persistent ear pain on one side without any ear infection.
Difficulty chewing or swallowing — Or trouble moving the tongue normally.
Neck lump — A swelling or lump on one side of the neck.
Regional context

Oral Cancer in Telangana & Andhra Pradesh

Telangana and Andhra Pradesh carry a particularly heavy oral cancer burden — driven almost entirely by chewed tobacco products (gutkha, zarda, khaini), paan with tobacco, and supari/areca-nut consumption. Crucially, these habits affect women in this region too: many women who have never smoked use chewing tobacco daily, and account for a significant share of oral cancers presenting at advanced stages.

A particular precancerous condition called oral submucous fibrosis (OSMF) — caused by chronic areca-nut use, with a stiffening of the cheeks and difficulty opening the mouth — is now seen even in teenagers in this region and progresses to oral cancer in a meaningful proportion of cases. Anyone with a daily chewing habit who notices a non-healing ulcer, a white or red patch, or restricted mouth opening should see an oncologist without delay.

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Meet the Specialists

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Dr. Naresh Gundu
Medical Oncologist

Dr. Naresh Gundu

MBBS, DNB (Internal Medicine), DM (Medical Oncology)

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Medical Oncologist

Dr. C. Raghavendra Reddy

MBBS(Gold Medal), DNB(General Medicine), DM(Medical Oncology)(Gold Medal)

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Medical Oncologist

Dr. Bharati Devi Gorantla

MBBS, MD(General Medicine), DM(Medical Oncology)(Adyar,Chennai), ECMO, MRCP SCE(UK)

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Dr. Owais Mohammed
Medical Oncologist

Dr. Owais Mohammed

MBBS, MD (General Medicine), DrNB (Medical Oncology), ECMO, MRCP SCE (Medical Oncology) (UK)

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Dr. T. Raghavender Reddy
Medical Oncologist

Dr. T. Raghavender Reddy

MBBS, DM (Medical Oncology), MD (Radiation Oncology)

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Dr. N. Kiranmayee
Medical Oncologist

Dr. N. Kiranmayee

MBBS, DM (Medical Oncology), MD (Internal Medicine)

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Dr. Muralidhar Muddusetty
Surgical Oncologist

Dr. Muralidhar Muddusetty

MBBS (AIIMS), MS (Surgery) (AIIMS), DNB (Surgical Oncology), MRCS (Edinburgh)

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Dr. Raghavendra Naik
Surgical Oncologist

Dr. Raghavendra Naik

MBBS, MS (General Surgery), M.Ch (Surgical Oncology)

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Dr. Mohammed  Imaduddin
Surgical Oncologist

Dr. Mohammed Imaduddin

M.B.B.S, MS (General Surgery), M.Ch (Surgical Oncology)

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Dr. Vinay Mamidala
Surgical Oncologist

Dr. Vinay Mamidala

MBBS, MS(General Surgery), M.Ch(Surgical Oncology), FMAS, FARIS(Ongoing)

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Dr. Paila Gowri Naidu
Surgical Oncologist

Dr. Paila Gowri Naidu

MBBS, MS (General Surgery), M.Ch (Surgical Oncology), FMAS

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Dr. Venkata Sushma P
Radiation Oncologist

Dr. Venkata Sushma P

MBBS, MD (Radiation Oncology)

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Radiation Oncologist

Dr. Kirti Ranjan Mohanty

MBBS, MD (Radiation Oncology)

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Dr. Gangadhar Vajrala
Radiation Oncologist

Dr. Gangadhar Vajrala

MBBS, MD (Radiation Oncology), MPH

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Dr. Basudev Pokhrel
Hematologist

Dr. Basudev Pokhrel

MBBS, M.D (Immunohematology & Blood Transfusion)

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Dr. Mohammed Imran
Interventional Radiologist

Dr. Mohammed Imran

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Dr. Vajja Sandeep Kumar
Surgical Oncologist

Dr. Vajja Sandeep Kumar

MBBS, MS (General Surgery), DrNB (Surgical Oncology), FALS Oncology

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Surgical Oncologist

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MBBS, MS (General Surgery), DrNB (Surgical Oncology)

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Causes of oral cancer

Common Causes & Risk Factors

Almost all oral cancers in India are linked to one or more of the following risk factors:

Chewed tobacco — gutkha, zarda, khaini, mawa, mishri.
Smoking — bidis, cigarettes, hookah, chillum.
Paan with tobacco — or areca-nut (supari) chewing.
Heavy alcohol — especially when combined with tobacco use.
Oral submucous fibrosis (OSMF) — a precancerous condition caused by areca-nut.
HPV infection — more relevant for oropharyngeal cancers.
Poor oral hygiene — chronic sharp tooth edges or ill-fitting dentures.
Chronic sun exposure — a known risk factor for lip cancer.
Family history — personal or family history of head and neck cancer.
Male sex, age 40+ — though oral cancer is increasingly seen in younger adults with chewing habits.
Outcome evidence

Oral Cancer Survival — CION vs National Average

Outcomes published by ICMR/NCRP for India versus 1-year survival rates achieved at CION across our oncology network.

Outcome CION National average Δ
Oral cancer 1-year survival* 80.0% 71.6% +8.4%

*1-year survival rates. Source: ICMR / National Cancer Registry Programme (NCRP) national averages compared with CION patient outcomes across the network.

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When to act

When to See an Oral Cancer Specialist

Any of the following should prompt an immediate visit to an oncologist or head-and-neck specialist:

Ulcer over 2 weeks old — a mouth sore or ulcer that has not healed in 2 weeks.
Mouth patches you can't wipe off — white, red, or mixed-colour patches inside the mouth.
Lump or thickening — felt inside the cheek, gum, tongue, or floor of the mouth.
Restricted mouth opening — or a stiffening of the cheeks (a hallmark of OSMF).
Unexplained loose teeth — in an otherwise healthy mouth.
One-sided ear pain — or a lump felt in the neck.
Any new symptom in someone with a chewing or smoking habit — don't wait it out.

A short specialist consultation and the right diagnostic test — imaging, endoscopy, biopsy, or blood test as appropriate — is usually enough to confirm or rule out cancer. Early action is always easier than catching up later.

A non-healing mouth ulcer, a white or red patch, or restricted mouth opening? Book a free consultation at your nearest CION Cancer Clinic.

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Care at CION

Specialist Oral Cancer Care at CION Cancer Clinics

Our NABH-accredited centres across Hyderabad deliver evidence-based oral cancer care — from biopsy and staging imaging through to wide local excision, neck dissection, reconstructive flap surgery, advanced radiation therapy (IMRT/IGRT), chemotherapy and immunotherapy — guided by NCCN and ESMO protocols and reviewed for every patient by a multidisciplinary tumour board with surgical, medical and radiation oncology input.

For a detailed walk-through of oral cancer diagnosis, treatment options, costs, and our specialist team, see our dedicated page on oral cancer treatment in Hyderabad.

Real patients · Real outcomes

15,000+ patients have walked this journey with us.

Hear from patients who came to CION with a mouth ulcer, a non-healing socket, or a biopsy report — and went back to normal life.

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Successful Chemotherapy Done by Dr. C Raghavendra Reddy

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 Successful Radical Thymectomy Done by  Dr. Mohammed Imaduddin & Dr. Vinay Mamidala

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Successful Buccal Mucosa Surgery

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Successful Complex Surgery Mandibulectomy Reconstruction

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Common questions

Frequently Asked Questions about Oral Cancer

What is the first sign of oral cancer?

The most common first sign is a mouth ulcer, sore or patch that does not heal within 2 weeks. Other early clues include a white or red patch inside the mouth, a thickened lump felt inside the cheek or under the tongue, restricted mouth opening, or unexplained loose teeth. Persistent one-sided ear pain without any ear infection is another important warning sign.

Is oral cancer curable?

Yes — oral cancer is highly curable when caught early. Stage I and Stage II oral cancers treated with surgery have 5-year survival rates of 75–90%. Even advanced oral cancers can often be cured with a combination of surgery, radiation, chemotherapy and immunotherapy. The single biggest factor in outcome is how early the cancer is diagnosed — and most oral cancers can be seen or felt during a 2-minute self-examination at home.

Does gutkha or chewing tobacco cause oral cancer?

Yes. Gutkha, zarda, khaini, mawa, paan with tobacco and areca-nut (supari) are all major causes of oral cancer in India. Chewing tobacco causes oral cancer through prolonged direct contact with the cheek lining, and areca-nut on its own causes oral submucous fibrosis — a precancerous condition that progresses to oral cancer in a significant proportion of cases. Stopping these habits, even after years of use, dramatically reduces the risk.

What is oral submucous fibrosis (OSMF)?

Oral submucous fibrosis is a precancerous condition almost entirely caused by chronic areca-nut and gutkha use. It progressively stiffens the lining of the cheeks, making it harder to open the mouth wide, and is often accompanied by burning sensations when eating spicy food. Without intervention, OSMF can progress to oral cancer. Anyone with restricted mouth opening or a daily chewing habit should be assessed by an oncologist.

Can oral cancer be prevented?

Yes — the great majority of oral cancers in India are preventable. Stopping all forms of tobacco and areca-nut use, limiting alcohol, treating chronic sharp tooth edges or ill-fitting dentures, maintaining good oral hygiene, and doing a 2-minute monthly self-examination of the mouth in front of a mirror are the most effective preventive measures.

Disclaimer: This page is intended for general informational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a qualified oncologist for guidance specific to your medical condition. Content on this page is periodically reviewed and updated by CION's medical team in accordance with current clinical guidelines.

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