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Intestinal cancer care · Hyderabad

Intestinal Cancer — Types, Symptoms & When to See a Specialist

Medically reviewed by Dr. T. Raghavender Reddy, MBBS, DM (Medical Oncology), MD (Radiation Oncology) · Last reviewed May 2026

Intestinal cancer covers cancers of both the small intestine and the large intestine (colon) — and across Telangana and Andhra Pradesh, both are slowly rising in incidence, particularly in younger adults. The challenge is that intestinal cancers often hide behind everyday digestive complaints, so awareness of the warning signs — and screening colonoscopy for those at risk — is the most effective early-detection strategy.

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Written by Dr. Mohammed Imaduddin — Surgical Oncologist · MBBS · MS (General Surgery) · M.Ch (Surgical Oncology) · CION Cancer Clinics, Hyderabad. Medically reviewed by Dr. T. Raghavender Reddy — Medical Oncologist · MBBS · DM (Medical Oncology) · MD (Radiation Oncology). Last reviewed May 2026.

Understanding the disease

What is Intestinal Cancer?

Intestinal cancer refers to malignant tumours that develop anywhere along the intestine — the long, coiled tube that digests and absorbs the food you eat. The small intestine includes the duodenum, jejunum and ileum, and is responsible for most digestion and nutrient absorption. The large intestine (colon) absorbs water and forms stool. Cancers can develop in any part of either, but the colon is by far the more common site.

Across India, colon cancer is rising steadily, with an increasing proportion of cases now in adults under 50. Small intestine cancers remain rare. Diets low in fibre, high in processed and red meat, rising obesity and diabetes, and decreasing physical activity are all contributing. The good news is that intestinal cancer found early is one of the most curable cancers, and screening colonoscopy — especially in those over 50 or with a family history — can detect and remove pre-cancerous polyps before they ever become cancer.

Did You Know?

Intestinal cancer is one of the most preventable cancers. A single screening colonoscopy from age 50 (or earlier with a family history) can detect and remove pre-cancerous polyps — interrupting the cancer journey before it begins. Most colon cancers grow from a polyp over 5 to 10 years, giving a long window to act.

Classification

Types of Intestinal Cancer

Intestinal cancers are classified by the part of the intestine they begin in and the cell type they arise from.

Most common

Colon Adenocarcinoma

By far the most common intestinal cancer. It develops in the lining of the large intestine, almost always from a pre-existing polyp. Treatment is primarily surgical (segmental colectomy with lymph node clearance), with chemotherapy for higher-stage disease, targeted therapy and immunotherapy in selected cases.

Rare

Small Intestine Adenocarcinoma

A rare cancer of the small bowel, most often in the duodenum. Usually diagnosed late because of vague symptoms. Treatment is surgical resection with adjuvant chemotherapy for higher stages.

Targeted therapy

Gastrointestinal Stromal Tumour (GIST)

Tumours of specialised cells in the wall of the small or large intestine. GIST is treated very differently from adenocarcinoma — often with targeted therapy (imatinib) combined with surgery.

Neuroendocrine

Carcinoid (Neuroendocrine Tumours)

Slow-growing tumours of hormone-producing cells, most commonly in the small intestine (particularly the ileum). May produce flushing, diarrhoea or wheezing when advanced (carcinoid syndrome). Many are cured with surgery alone.

Lymphoid

Intestinal Lymphoma

Cancers of the immune cells of the intestine, including primary intestinal lymphoma and lymphomas associated with chronic conditions such as coeliac disease. Treated primarily with chemotherapy.

Connective tissue

Intestinal Sarcoma

A rare group of cancers of the connective tissue of the intestinal wall. Requires specialist multidisciplinary management.

For detailed information on diagnosis, laparoscopic and robotic colectomy, and modern systemic therapy, see our dedicated page on intestinal cancer treatment in Hyderabad.

Recognising the warning signs

Common Signs & Symptoms of Intestinal Cancer

Intestinal cancer often produces vague symptoms in its early stages that overlap with routine digestive issues. Watch for any of the following — especially if they last more than 3 weeks:

Persistent change in bowel habit — new constipation, diarrhoea, or alternating between the two.
Blood in the stool, or black or tarry stools.
Unexplained iron-deficiency anaemia — especially in men or postmenopausal women.
Persistent abdominal pain, cramping, or bloating.
A feeling of incomplete emptying after passing stools.
Unexplained weight loss or loss of appetite.
Persistent tiredness or weakness.
A lump or mass felt in the abdomen.
Sudden bowel obstruction — severe abdominal pain, vomiting, inability to pass stools.

Worried about a change in bowel habit?

A change in bowel habit, persistent abdominal pain, or unexplained anaemia? Book a free consultation at your nearest CION Cancer Clinic.

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Meet the Specialists

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Dr. Naresh Gundu
Medical Oncologist

Dr. Naresh Gundu

MBBS, DNB (Internal Medicine), DM (Medical Oncology)

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Dr. C. Raghavendra Reddy
Medical Oncologist

Dr. C. Raghavendra Reddy

MBBS(Gold Medal), DNB(General Medicine), DM(Medical Oncology)(Gold Medal)

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Dr. Bharati Devi Gorantla
Medical Oncologist

Dr. Bharati Devi Gorantla

MBBS, MD(General Medicine), DM(Medical Oncology)(Adyar,Chennai), ECMO, MRCP SCE(UK)

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Dr. Owais Mohammed
Medical Oncologist

Dr. Owais Mohammed

MBBS, MD (General Medicine), DrNB (Medical Oncology), ECMO, MRCP SCE (Medical Oncology) (UK)

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Dr. T. Raghavender Reddy
Medical Oncologist

Dr. T. Raghavender Reddy

MBBS, DM (Medical Oncology), MD (Radiation Oncology)

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Dr. N. Kiranmayee
Medical Oncologist

Dr. N. Kiranmayee

MBBS, DM (Medical Oncology), MD (Internal Medicine)

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Dr. Muralidhar Muddusetty
Surgical Oncologist

Dr. Muralidhar Muddusetty

MBBS (AIIMS), MS (Surgery) (AIIMS), DNB (Surgical Oncology), MRCS (Edinburgh)

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Dr. Raghavendra Naik
Surgical Oncologist

Dr. Raghavendra Naik

MBBS, MS (General Surgery), M.Ch (Surgical Oncology)

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Dr. Mohammed  Imaduddin
Surgical Oncologist

Dr. Mohammed Imaduddin

M.B.B.S, MS (General Surgery), M.Ch (Surgical Oncology)

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Dr. Vinay Mamidala
Surgical Oncologist

Dr. Vinay Mamidala

MBBS, MS(General Surgery), M.Ch(Surgical Oncology), FMAS, FARIS(Ongoing)

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Dr. Paila Gowri Naidu
Surgical Oncologist

Dr. Paila Gowri Naidu

MBBS, MS (General Surgery), M.Ch (Surgical Oncology), FMAS

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Dr. Venkata Sushma P
Radiation Oncologist

Dr. Venkata Sushma P

MBBS, MD (Radiation Oncology)

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Dr. Kirti Ranjan Mohanty
Radiation Oncologist

Dr. Kirti Ranjan Mohanty

MBBS, MD (Radiation Oncology)

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Dr. Gangadhar Vajrala
Radiation Oncologist

Dr. Gangadhar Vajrala

MBBS, MD (Radiation Oncology), MPH

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Dr. Basudev Pokhrel
Hematologist

Dr. Basudev Pokhrel

MBBS, M.D (Immunohematology & Blood Transfusion)

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Dr. Mohammed Imran
Interventional Radiologist

Dr. Mohammed Imran

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Dr. Vajja Sandeep Kumar
Surgical Oncologist

Dr. Vajja Sandeep Kumar

MBBS, MS (General Surgery), DrNB (Surgical Oncology), FALS Oncology

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Dr. Sridhar Kamani
Surgical Oncologist

Dr. Sridhar Kamani

MBBS, MS (General Surgery), DrNB (Surgical Oncology)

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Regional context

Intestinal Cancer in Telangana & Andhra Pradesh

Colon cancer is rising steadily across Telangana and Andhra Pradesh, and an increasing share of cases are now in adults under 50 — younger than the typical Western pattern. Three regional drivers stand out: shifting diets (more refined carbohydrates, processed and packaged foods, red meat; less fibre and traditional millet-based grains), rapidly rising obesity and type 2 diabetes, and a general lack of awareness about screening colonoscopy. Small intestine cancers remain rare, but should be considered in anyone with unexplained chronic abdominal pain, iron-deficiency anaemia, or recurrent partial bowel obstruction. Anyone over 50 — or anyone of any age with a family history of bowel cancer or polyps — should discuss screening colonoscopy with their doctor.

Risk profile

Common Causes & Risk Factors

Intestinal cancers typically develop slowly over years, often from pre-existing polyps or chronic inflammation. Key risk factors include:

Age above 50 — although incidence is rising in younger adults.
Family history of colorectal cancer or adenomatous polyps.
Inherited syndromes — Lynch syndrome and familial adenomatous polyposis (FAP).
Personal history of colorectal polyps or inflammatory bowel disease (Crohn's disease, ulcerative colitis).
Coeliac disease — raises risk of small intestine lymphoma and adenocarcinoma.
Diets high in red and processed meat and low in fibre, fruits and vegetables.
Obesity and physical inactivity.
Type 2 diabetes.
Smoking and heavy alcohol use.
Previous radiation therapy to the abdomen or pelvis.
Triggers for evaluation

When to See an Intestinal Cancer Specialist

Any of the following should prompt a colonoscopy or imaging evaluation and specialist review, regardless of age:

A change in bowel habit lasting more than 3 weeks.
Blood in the stool, dark or tarry stools.
Unexplained iron-deficiency anaemia, especially in men or postmenopausal women.
Persistent abdominal pain, cramping or unexplained weight loss.
An abdominal mass, or recurrent partial bowel obstruction.
A family history of colorectal cancer or polyps — screening from age 40 or earlier may be appropriate.
Long-standing inflammatory bowel disease without recent surveillance.

A short specialist consultation and the right diagnostic test — imaging, endoscopy, biopsy, or blood test as appropriate — is usually enough to confirm or rule out cancer. Early action is always easier than catching up later.

Outcomes that matter

CION Outcomes vs National Average

Across the cancers we treat, CION patients consistently achieve higher 1-year survival than the national average. Intestinal cancer–specific survival is documented on our intestinal cancer treatment page; the figures below are the canonical CION-vs-national 1-year survival rates published across our care pathways.

Breast Cancer
96.9% CION
vs 85.4% national · +11.5%
Cervical Cancer
83.3% CION
vs 67.3% national · +16.0%
Ovarian Cancer
81.0% CION
vs 73.7% national · +7.3%
Oral Cancer
80.0% CION
vs 71.6% national · +8.4%

*1-year survival. Source: ICMR / NCRP for national figures; CION internal patient registry.

Get expert care at CION

Specialist Intestinal Cancer Care at CION Cancer Clinics

Our NABH-accredited centres across Hyderabad deliver evidence-based intestinal cancer care — from colonoscopy and CT/MRI staging through to laparoscopic and robotic-assisted colectomy, small bowel resection, complete mesocolic excision (CME), adjuvant and palliative chemotherapy, targeted therapy and modern immunotherapy combinations — guided by NCCN and ESMO protocols and reviewed for every patient by a multidisciplinary tumour board.

For a detailed walk-through of intestinal cancer diagnosis, treatment options, costs, and our specialist team, see our dedicated page on intestinal cancer treatment in Hyderabad.

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Successful Chemotherapy Done by Dr. C Raghavendra Reddy

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Successful Chemo & Surgery Done by Dr. Owais Mohammed & Dr. Imaduddin Mohammed

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Successful Chemotherapy Done by Dr. Gundu Naresh

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Common questions

Frequently asked questions about intestinal cancer

What is the first sign of intestinal cancer?

The most common first signs are a persistent change in bowel habit lasting more than 3 weeks, blood in the stool, dark or tarry stools, unexplained iron-deficiency anaemia, or persistent abdominal pain. Many early intestinal cancers cause no specific symptoms at all and are detected during screening colonoscopy or on tests done for unexplained anaemia. The unifying theme is persistence — a single bad day is rarely cancer, but a symptom that does not settle deserves evaluation.

What is the difference between intestinal cancer and colon cancer?

Colon cancer is a type of intestinal cancer. The term 'intestinal cancer' covers cancers of both the small intestine and the large intestine (colon), while 'colon cancer' refers specifically to cancers of the large bowel. Colon cancers are far more common than small intestine cancers, which is why people often use the two terms interchangeably.

Is intestinal cancer curable?

Yes — intestinal cancer is highly curable when caught early. Stage I colon cancer has 5-year survival rates above 90%. Even locally advanced disease can often be cured with surgery and chemotherapy. Modern laparoscopic and robotic techniques mean shorter hospital stays and faster recovery. Advanced disease is managed with chemotherapy, targeted therapy and immunotherapy where appropriate, with significantly improved outcomes in the last decade.

Who is at higher risk of intestinal cancer?

Adults over 50, those with a family history of colorectal cancer or polyps, individuals with Lynch syndrome or familial adenomatous polyposis, people with long-standing inflammatory bowel disease (Crohn's or ulcerative colitis), individuals with coeliac disease (for small bowel cancer), smokers, heavy drinkers, and those with obesity, type 2 diabetes or low-fibre diets are at elevated risk.

How can intestinal cancer be prevented?

Intestinal cancer is one of the most preventable cancers. Screening colonoscopy from age 50 (or earlier with a family history) can detect and remove pre-cancerous polyps before they ever become cancer. Lifestyle changes that meaningfully reduce risk include a high-fibre diet rich in fruits, vegetables and whole grains, limiting red and processed meats, maintaining a healthy weight, regular physical activity, stopping smoking and limiting alcohol.

Disclaimer: This page is intended for general informational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a qualified oncologist for guidance specific to your medical condition. Content on this page is periodically reviewed and updated by CION's medical team in accordance with current clinical guidelines.

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