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Endoscopic resection for early stomach cancer | CION Cancer Clinics

Some stomach cancers found very early, while still confined to the inner lining, can be removed whole by ESD through a scope passed down the mouth. The stomach stays in place. In India most stomach cancers are found later, so this is less common. This page explains who ESD suits, what the laboratory report decides, and when an operation is still advised. CION Cancer Clinics’ surgical oncologists in Hyderabad can talk this through with you.

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Medically reviewed by Dr. Mohammed ImaduddinConsultant Surgical Oncologist · MBBS, MS (General Surgery), MCh (Surgical Oncology) · last reviewed September 2026, next review due September 2027
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The short answer

Can early stomach cancer be removed with a scope instead of an operation?

Sometimes, yes. A stomach cancer found while it is still confined to the inner lining, is small, has no deep ulcer and has a well-organised cell type can often be removed by ESD through a scope passed down the mouth. The stomach stays in place, and there is no cut on the belly.

Why ESD is the usual technique in the stomach

ESD, or endoscopic submucosal dissection, cuts underneath the growth so it comes away in one whole piece. In the stomach this matters, because the laboratory must see every edge and measure exactly how deep the cancer went. That report decides whether scope removal was enough.

Why it is less common in India than in some countries

Countries such as Japan and Korea screen for stomach cancer, so many cancers there are found at this early stage. In India, most stomach cancers are found later, after symptoms such as weight loss or trouble eating, when an operation or chemotherapy is more likely to be needed. ESD is also done only in a limited number of Indian centres with trained teams.

What surgery offers that ESD cannot

An operation removes the lymph glands around the stomach. ESD does not. When the chance of spread to those glands is low, that trade-off favours ESD. When it is higher, surgery is usually advised.

The procedure

What happens during ESD for the stomach?

Getting ready

You will not eat for several hours beforehand. The anaesthetist checks your health and medicines. Tell the team about any blood thinner, such as aspirin or clopidogrel, and let your doctors decide what to do with it.

Marking the edges

Under sedation or general anaesthetic, the endoscopist studies the growth closely, often with dye or magnified views, then burns small dots around it with a margin of normal lining.

Lifting and cutting

Fluid is injected underneath to raise the growth. A fine electric knife cuts around the dots, then slowly underneath, sealing bleeding points as it goes, until the growth comes free whole.

Recovery on the ward

You usually stay in hospital for a short time. Eating starts with sips, then liquids and soft food. Acid-lowering tablets help the raw area in the stomach heal.

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The laboratory report

What can the report say, and what happens next?

The removed piece is examined in detail. Broadly, the report leads to one of three paths.

Removed completely, low risk

The edges are clear, the cancer stayed shallow and no cancer cells are seen in vessels. The team usually advises regular check scopes rather than further treatment.

What follows

  • Check scopes, with gaps that lengthen over time
  • Treatment of H. pylori, if present

Borderline findings

The edge is unclear, or the growth was slightly larger than expected, but the depth and cell type are still reassuring. A repeat scope, a second removal or closer follow-up may be offered.

Features of higher risk

The cancer went deeper than expected, has an aggressive cell type, or is seen inside tiny vessels. An operation to remove part of the stomach and nearby glands is usually discussed.

This is the plan working, not the ESD failing.

On your report

What do the words on a stomach ESD report mean?

Early gastric cancer
Stomach cancer confined to the inner lining or the layer just beneath, whether or not glands are involved.
Intestinal type
A cancer made of cells that form organised tube-like shapes. It is more often suitable for ESD.
Diffuse or signet ring cell
A cancer whose cells spread out singly rather than forming shapes. It tends to behave more aggressively.
En bloc resection
The growth came out in one piece, which is what ESD aims for.
Lymphovascular invasion
Cancer cells seen inside tiny blood or lymph vessels. It usually leads to a discussion about surgery.

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Commonly believed

What do families believe about stomach cancer and scopes?

"Stomach cancer always means removing the stomach."

Not when it is found very early. Some early cancers can be removed through a scope, leaving the stomach whole. This is why a scope for persistent indigestion or unexplained weight loss is worth doing sooner rather than later.

"Once the cancer is out, the stomach is safe."

The rest of the stomach lining can develop a new early cancer, particularly where H. pylori has damaged it. Regular check scopes are part of the plan, not an optional extra.

"H. pylori is just a gastric infection, it has nothing to do with this."

This common stomach germ is a leading cause of stomach cancer. Testing for it and clearing it with a course of medicines is usually part of care after ESD.

"If they recommend surgery after ESD, the first doctor got it wrong."

The laboratory report on the whole piece is more accurate than anything seen before removal. Surgery afterwards is a planned possibility, not proof of a mistake.

Being straight with you

Who is ESD not suitable for, and what can this page not tell you?

ESD is not suitable when a stomach cancer has grown deep into the wall, spread to glands or other organs, or has a deep ulcer or an aggressive cell type. It is also not usually used for a cancer found after symptoms such as vomiting, weight loss or a blocked stomach, because those are usually signs of a more advanced cancer.

What to ask the centre

Ask how often the unit performs stomach ESD, who reads the laboratory specimen, and what happens if a tear or bleeding occurs. A surgical team should be available if needed.

When general health changes the picture

For someone frail or with serious heart or lung disease, a team may weigh ESD differently, because an operation carries more risk for them. That is a judgement for the treating team with the patient and family.

What this page cannot tell you

It cannot tell you whether your cancer qualifies or what your report will show. Only your scope pictures, biopsy, scans and the final laboratory report can.

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One thing that cannot wait

Bleeding from the raw area can happen days after going home. If you vomit blood or dark material like coffee grounds, pass black stools, feel faint or dizzy, or have severe belly pain with a fever, go to the nearest emergency department the same day. Say you have had an ESD of the stomach and take your discharge papers. Do not wait to see whether it settles.

Questions we are asked

Common questions about ESD for early stomach cancer

Is ESD available for stomach cancer in India?

Yes, but only in some centres with trained endoscopists and a supporting surgical team. It is not offered everywhere that does routine scopes. Ask the centre how often it performs stomach ESD and what happens if a problem arises during the procedure.

How do I know if my stomach cancer is early enough?

You cannot tell from symptoms or from how you feel. The team uses close scope views, biopsy results and sometimes a CT scan or ultrasound scope to judge depth and spread. The final answer on depth only comes from the laboratory report after removal.

Will I be able to eat normally afterwards?

Because the stomach is kept, most people return to their usual food once the raw area has healed. In the first days you move slowly from liquids to soft food. Spicy, very hot and hard foods are often avoided for a while. Your team will give written instructions.

Do I need to take medicines after ESD?

Acid-lowering tablets are usually prescribed to help the raw area heal. If H. pylori is found, a course of antibiotics and acid-lowering tablets is given to clear it. Take them exactly as prescribed and ask before stopping any of them.

What are the main risks?

The main risks are bleeding, during or after the procedure, and a tear in the stomach wall. Most are managed through the scope, but some need an operation. Narrowing is uncommon in the stomach unless the growth was near its entry or exit. Ask your team to explain the risks for your growth.

Should family members be checked too?

Close family often share H. pylori infection, and some families carry a higher risk of stomach cancer. It is reasonable to ask your doctor whether relatives should be tested for H. pylori or offered a scope, especially if more than one relative has had stomach cancer.

How often will I need check scopes?

Usually the first check is a few months after ESD, then at regular intervals that lengthen if all is well. The exact schedule depends on your report and your team's practice. Keeping these appointments matters, because new early growths can appear elsewhere in the stomach.

Is ESD covered by Aarogyasri or insurance?

Coverage depends on the scheme and whether cancer has been confirmed. Aarogyasri, CGHS, ECHS and EHS may apply, and many cashless insurers cover it as an inpatient procedure. Call the helpline with your reports and card details so your cover can be checked before the date is fixed.

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Dr. Owais Mohammed
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Dr. Owais Mohammed

MBBS, MD (General Medicine), DrNB (Medical Oncology), ECMO, MRCP SCE (Medical Oncology) (UK)

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Dr. T. Raghavender Reddy
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MBBS, DM (Medical Oncology), MD (Radiation Oncology)

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Dr. N. Kiranmayee
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MBBS, DM (Medical Oncology), MD (Internal Medicine)

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MBBS (AIIMS), MS (Surgery) (AIIMS), DNB (Surgical Oncology), MRCS (Edinburgh)

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Dr. Raghavendra Naik
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MBBS, MS (General Surgery), M.Ch (Surgical Oncology)

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Dr. Mohammed  Imaduddin
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M.B.B.S, MS (General Surgery), M.Ch (Surgical Oncology)

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Dr. Vinay Mamidala
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Dr. Kirti Ranjan Mohanty
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Sources

  1. National Cancer Institute — Gastric cancer treatment (PDQ), patient version
  2. Cancer Research UK — Stomach cancer
  3. American Cancer Society — Stomach cancer
  4. NHS — Stomach cancer
  5. NICE — Oesophago-gastric cancer: assessment and management in adults (NG83)

This page is general information, not a prescription. Do not change or stop any treatment based on what you read here. If anything is worrying you, contact your own treating team — or call our helpline and we will help you reach the right specialist.

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Told you have an early stomach cancer?

Send us the scope and biopsy reports. A CION surgical oncologist will explain what the team is weighing and what to ask. One helpline serves every CION centre.

Call 1800 202 8726

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Where to find us

Our centres in and around Hyderabad

Addressed by landmark, because that is how this city navigates. A surgical consultation can be booked at any of these centres through one helpline, and your team will tell you where the operation itself takes place.

CION Ameerpet

Beside Blue Fox Hotel, Satyam Theatre Road

Begumpet SR Nagar Punjagutta
CION Kukatpally

Opposite Big Bazaar, Mumbai Highway

KPHB JNTU Bharat Nagar
CION L.B. Nagar

Anu Arcade, next to L.B. Nagar Metro station

Vanasthalipuram Nagole Hayathnagar
CION Tolichowki

Inside Premier Hospital, Khader Bagh Road

Mehdipatnam Attapur Rethibowli
CION Masab Tank

Mahavir Hospital, AC Guards, Lakdikapul

Lakdikapul Khairatabad Basheer Bagh
CION Banjara Hills

Road No. 12

Jubilee Hills Madhapur Film Nagar
CION Kompally

Suchitra Circle, NH-44

Suchitra Circle Alwal Dundigal
CION Balanagar

Balanagar Main Road

Balanagar Fatehnagar Moosapet
CION Siddipet

Lohith Sai Hospital, Shivaji Nagar

Gajwel Husnabad Dubbaka
CION Sangareddy

X Roads, Pothreddipalle

Narayankhed Zaheerabad Patancheru
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