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When is pain after cancer surgery abnormal? | CION Cancer Clinics

Normal pain after cancer surgery is worst in the first few days and then eases a little each day. Pain that gets worse after it was settling, stops responding to your painkillers, or comes with fever, vomiting, breathlessness or a swollen leg is not normal. This page shows the patterns to report, what to tell the doctor, and what needs emergency care. CION Cancer Clinics’ surgical oncologists in Hyderabad can talk this through with you.

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Medically reviewed by Dr. Muralidhar MuddusettyConsultant Surgical Oncologist · MBBS (AIIMS), MS (Surgery, AIIMS), DNB (Surgical Oncology), MRCS (Edinburgh) · last reviewed September 2026, next review due September 2027
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The short answer

How do you tell if pain after surgery is not normal?

Normal pain after surgery is worst in the first few days and then eases a little each day. Pain that gets worse after it was easing, pain that painkillers no longer touch, or pain that comes with fever, vomiting, breathlessness or a swollen leg is not normal and needs a doctor.

What expected pain looks like

Soreness around the cut, worse when you move, cough or get out of bed. Aching from drains and tubes. Stiff muscles from lying still. It responds to the painkillers you were given, and each day you can do a little more than the day before.

The pattern matters more than the score

A high pain score on the first day can be normal. A lower score that starts climbing again several days later is more worrying. Doctors look at the direction of travel: is it settling, flat, or getting worse?

Why this matters at home

Many people go home before the wound has fully healed. Problems such as infection, a leak inside, or a blood clot can appear after discharge. Pain is often the first sign, so it is worth taking a change seriously.

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One thing that cannot wait

Go to the nearest emergency department straight away if pain comes with sudden breathlessness, chest pain, fainting, a fast heartbeat, vomiting with a swollen hard stomach, high fever with shivering, or confusion. Take your discharge summary with you and say you have just had surgery. Do not take extra painkillers and wait to see if it settles.

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Patterns to report

Which kinds of pain can point to a problem?

None of these proves something is wrong. Each one is a reason to call your surgical team the same day.

A wound that is getting worse

Pain increasing around the cut, with redness spreading, heat, swelling, a bad smell, or pus or cloudy fluid leaking out. This can mean infection.

Pain deep in the stomach

Pain that spreads across the whole tummy, gets steadily worse, and comes with fever, vomiting or a swollen stomach. After bowel or stomach surgery, this can mean a leak where the gut was joined.

A painful, swollen leg

Pain in one calf or thigh, with swelling, warmth or redness. This can mean a blood clot in a deep vein. It needs checking the same day.

Go to emergency if also

  • Sudden breathlessness
  • Chest pain when breathing in

Pain nothing seems to touch

Pain that is far worse than the day before, or no longer eases with the medicines that worked earlier. This alone is reason enough to call.

The usual course

What does ordinary recovery pain usually look like over time?

  1. The first few days

    Pain is at its strongest. It is controlled with a drip, a pump, an epidural or strong tablets. Nurses ask you to score it many times a day. Moving, coughing and deep breaths hurt, but you can still do them with support.

  2. Towards going home

    Pain has usually moved to tablets. You can walk to the toilet and sleep for longer stretches. The wound is tender to touch but not getting redder or more swollen.

  3. The first weeks at home

    Soreness eases steadily, though you may have a bad day after doing too much. Tiredness is common. You need less painkiller as the days go on.

  4. After the wound has healed

    Most pain has gone. Some numbness, tightness or odd sensations around the scar can last much longer. Pain that stays or returns months later is worth raising at follow-up.

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Side by side

Expected pain or a warning sign?

Usually expected Call the team the same day
Pain easing a little each day Pain getting worse after it had started to ease
Tenderness right around the cut Spreading redness, heat, pus or a bad smell
Pain that settles with your painkillers Pain that no longer eases with the same medicines
Aching in the shoulders after keyhole surgery Pain with fever, vomiting or a swollen leg

Commonly believed

What stops families calling the doctor in time?

"Surgery is supposed to hurt, so we should not complain."

Some pain is expected, but a change in the pattern is information the team needs. Calling about a worry that turns out to be nothing is far better than waiting on a problem that grows.

"We will wait for the follow-up appointment."

The follow-up date was set for a normal recovery. If something has changed, call the surgical team now. They would rather see you early.

"More painkillers will sort it out."

Taking extra doses can hide a fever or an infection while it gets worse, and it risks overdose. Do not change the dose on your own. Call instead.

"She is older, so she will just feel more pain."

Older people sometimes show a problem as confusion, drowsiness or not eating rather than as pain. A sudden change in how an older relative is behaving after surgery is a reason to call, even if they say the pain is fine.

Being straight with you

What should you tell the doctor, and what can this page not tell you?

This page cannot tell you whether your own pain is normal. The operation you had, the joins made inside, and your other conditions all change what counts as expected. Only someone who can examine you, and sometimes order a blood test or scan, can answer that.

How to describe the pain on the phone

Say where it is, when it started, and whether it is getting better or worse. Say whether it is sharp, burning, cramping or aching, and what makes it worse. Mention any fever, vomiting, stool or urine changes, wound changes, or a swollen leg. Have your discharge summary and medicine list in front of you.

Pain that has other causes

Not all pain after surgery comes from the operation site. Shoulder tip pain after keyhole surgery, a stiff back from the operating table, constipation from painkillers, and burning nerve pain around a scar are all common. They still deserve a mention to the team, because the treatment is different for each.

If you are unsure whether to call, call. Keep the surgical team's number and the nearest emergency department written down at home.

Questions we are asked

Common questions about abnormal pain after surgery

Is it normal for pain to get worse a few days after surgery?

A brief rise after doing more, or when a pain pump or epidural is stopped, can be normal. Pain that keeps getting worse day after day, or comes with fever, vomiting, redness at the wound or a swollen leg, is not. Call your surgical team the same day if you are unsure.

How do I know if my wound is infected?

Signs include increasing pain around the cut, redness that spreads, warmth, swelling, pus or cloudy fluid, a bad smell, the wound edges opening, or fever. A little clear or pinkish fluid early on can be normal. Take a photo each day so you can show the team how it has changed.

Can I just take more of my painkillers?

No. Taking more than prescribed can cause overdose, stomach bleeding or liver damage, depending on the medicine. It can also hide a warning sign. If the prescribed dose is not controlling the pain, that itself is something to report. Call the team and let them decide.

What does pain in the calf after surgery mean?

It can be a strained muscle from lying still, but it can also be a blood clot in a deep vein. A clot is more likely if the calf is swollen, warm or red on one side. Get it checked the same day, and go to emergency if you also feel breathless or have chest pain.

I had keyhole surgery. Why does my shoulder hurt?

The gas used to lift the tummy wall during keyhole surgery can irritate a nerve, and the pain is felt in the shoulder. It is common and usually settles within days. Chest pain, breathlessness or shoulder pain that keeps getting worse is different and needs a same-day check.

Who should I call at night or on a holiday?

Use the number on your discharge summary first. If you cannot reach the team and the symptoms feel serious, go to the nearest emergency department. Take the discharge summary, your medicine list and any recent reports. Tell them clearly what operation you had and when.

My father says he is fine but he seems confused. Should we worry?

Yes. In older people, new confusion, drowsiness or refusing food can be the first sign of infection, dehydration or a medicine side effect, even with little pain. Call the surgical team the same day, and go to emergency if he is very hard to wake or breathing badly.

Could the pain mean the cancer has come back?

In the weeks after surgery, pain is far more likely to come from healing or a complication. Pain that appears or returns months later, in a new place, should be checked, but many causes are harmless. This page cannot tell you which it is. Raise it with your doctor rather than waiting.

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Dr. Naresh Gundu
Medical Oncologist

Dr. Naresh Gundu

MBBS, DNB (Internal Medicine), DM (Medical Oncology)

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Dr. C. Raghavendra Reddy
Medical Oncologist

Dr. C. Raghavendra Reddy

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Dr. Bharati Devi Gorantla
Medical Oncologist

Dr. Bharati Devi Gorantla

MBBS, MD(General Medicine), DM(Medical Oncology)(Adyar,Chennai), ECMO, MRCP SCE(UK)

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Dr. Owais Mohammed
Medical Oncologist

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MBBS, MD (General Medicine), DrNB (Medical Oncology), ECMO, MRCP SCE (Medical Oncology) (UK)

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Dr. T. Raghavender Reddy
Medical Oncologist

Dr. T. Raghavender Reddy

MBBS, DM (Medical Oncology), MD (Radiation Oncology)

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Dr. N. Kiranmayee
Medical Oncologist

Dr. N. Kiranmayee

MBBS, DM (Medical Oncology), MD (Internal Medicine)

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Dr. Muralidhar Muddusetty
Surgical Oncologist

Dr. Muralidhar Muddusetty

MBBS (AIIMS), MS (Surgery) (AIIMS), DNB (Surgical Oncology), MRCS (Edinburgh)

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Dr. Raghavendra Naik
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MBBS, MS (General Surgery), M.Ch (Surgical Oncology)

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Dr. Mohammed  Imaduddin
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Dr. Mohammed Imaduddin

M.B.B.S, MS (General Surgery), M.Ch (Surgical Oncology)

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Dr. Vinay Mamidala
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MBBS, MS(General Surgery), M.Ch(Surgical Oncology), FMAS, FARIS(Ongoing)

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Dr. Paila Gowri Naidu
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Dr. Paila Gowri Naidu

MBBS, MS (General Surgery), M.Ch (Surgical Oncology), FMAS

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Dr. Venkata Sushma P
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Dr. Venkata Sushma P

MBBS, MD (Radiation Oncology)

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Dr. Kirti Ranjan Mohanty
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Dr. Gangadhar Vajrala
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Dr. Basudev Pokhrel
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MBBS, M.D (Immunohematology & Blood Transfusion)

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Dr. Vajja Sandeep Kumar
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Dr. Vajja Sandeep Kumar

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Dr. Sridhar Kamani
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Dr. Sridhar Kamani

MBBS, MS (General Surgery), DrNB (Surgical Oncology)

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Sources

  1. NHS — Deep vein thrombosis (DVT)
  2. NHS — Sepsis
  3. National Cancer Institute — Cancer pain
  4. Cancer Research UK — Surgery for cancer

This page is general information, not a prescription. Do not change or stop any treatment based on what you read here. If anything is worrying you, contact your own treating team — or call our helpline and we will help you reach the right specialist.

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Not sure what to do next?

Tell us what has been found so far and we will help you reach the right specialist. One helpline serves every CION centre.

Call 1800 202 8726

Speak to an oncologist

Where to find us

Our centres in and around Hyderabad

Addressed by landmark, because that is how this city navigates. A surgical consultation can be booked at any of these centres through one helpline, and your team will tell you where the operation itself takes place.

CION Ameerpet

Beside Blue Fox Hotel, Satyam Theatre Road

Begumpet SR Nagar Punjagutta
CION Kukatpally

Opposite Big Bazaar, Mumbai Highway

KPHB JNTU Bharat Nagar
CION L.B. Nagar

Anu Arcade, next to L.B. Nagar Metro station

Vanasthalipuram Nagole Hayathnagar
CION Tolichowki

Inside Premier Hospital, Khader Bagh Road

Mehdipatnam Attapur Rethibowli
CION Masab Tank

Mahavir Hospital, AC Guards, Lakdikapul

Lakdikapul Khairatabad Basheer Bagh
CION Banjara Hills

Road No. 12

Jubilee Hills Madhapur Film Nagar
CION Kompally

Suchitra Circle, NH-44

Suchitra Circle Alwal Dundigal
CION Balanagar

Balanagar Main Road

Balanagar Fatehnagar Moosapet
CION Siddipet

Lohith Sai Hospital, Shivaji Nagar

Gajwel Husnabad Dubbaka
CION Sangareddy

X Roads, Pothreddipalle

Narayankhed Zaheerabad Patancheru
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