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Has radical surgery become less common? | CION Cancer Clinics

For many cancers, yes. Trials showed that a smaller operation, often with radiotherapy or chemotherapy, can control certain early cancers as well as the much larger operation used before. But radical surgery has not disappeared. For some cancers it is still the main way to remove the disease. This page explains why practice changed, where it did not, and what that means when an operation is being planned for you. CION Cancer Clinics’ surgical oncologists in Hyderabad can talk this through with you.

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Medically reviewed by Dr. Muralidhar MuddusettyConsultant Surgical Oncologist · MBBS (AIIMS), MS (Surgery, AIIMS), DNB (Surgical Oncology), MRCS (Edinburgh) · last reviewed September 2026, next review due September 2027
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The short answer

Has cancer surgery really become smaller?

Yes, for many cancers it has. Over several decades, careful studies showed that a smaller operation, often combined with radiotherapy or medicines, can control certain early cancers as well as the much larger operation used before.

Why the change happened

Three things moved together. Trials tested smaller operations directly against bigger ones in the same kind of patient. Scans and screening began finding cancers earlier, when they are smaller. And radiotherapy, chemotherapy and newer medicines became good enough to deal with cancer cells a smaller operation might leave nearby.

Why it has not happened everywhere

The trend is real, but it is uneven. For some cancers, the thorough operation is still the main way to remove the disease. For a few, surgery has become more careful about taking lymph nodes and surrounding tissue, not less. What changed is that the size of the operation is now matched to the cancer, rather than one large operation for everyone.

This page describes a general trend. It cannot tell you which operation suits your own cancer. That depends on its type, stage and position, which your treating team will explain.

How it changed

How did surgeons move from bigger operations to smaller ones?

  1. The era of the largest operations

    For much of the last century, surgeons believed cancer spread outwards step by step. The answer seemed to be removing as much as possible. For breast cancer, that meant taking the breast, the chest muscle and all the armpit nodes.

  2. Trials tested the belief

    Researchers then compared smaller operations with the large ones in patients with similar cancers. For suitable early breast cancer, removing only the lump followed by radiotherapy did as well as removing the whole breast.

  3. Checking the first node instead of all of them

    Sentinel node biopsy arrived. The surgeon removes the first one or few nodes the cancer would drain to. If those are clear, the rest can often stay.

  4. Keeping organs and limbs

    For many sarcomas of the arm or leg, removing the tumour with radiotherapy replaced amputation. For some cancers of the voice box and the back passage, radiotherapy with chemotherapy became the first treatment, with surgery kept in reserve.

  5. Matching surgery to the cancer

    Today the team looks at the cancer's type, stage and behaviour, and chooses the smallest operation that still removes it properly.

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Where it shows

Which cancers saw the biggest change?

These are the most studied examples. In each, the smaller approach suits a particular group, not everyone with that cancer.

Breast cancer

Breast-conserving surgery with radiotherapy is now common for early cancers. Sentinel node biopsy has replaced clearing the whole armpit for many women.

Sarcoma of the arm or leg

Limb-sparing surgery, usually with radiotherapy, is now the usual aim. Amputation is kept for tumours that cannot be removed any other way.

Voice box and back passage

For some cancers of the larynx and the anus, chemotherapy with radiotherapy can keep the organ working. Surgery is offered if the cancer stays or returns.

Kidney and skin

Small kidney tumours are often removed with part of the kidney rather than all of it. For melanoma, the rim of skin removed has become narrower than it once was.

Each of these suits selected cancers only.

Side by side

What pushed the change, and what still holds it back?

What made smaller surgery possible What still limits it
Cancers found earlier, when they are smaller Many cancers in India are still found late, when they are large
Radiotherapy that deals with cells left nearby Radiotherapy needs daily visits for weeks, which is hard from a distant district
Chemotherapy that shrinks a tumour before surgery Not every cancer shrinks enough to change the operation
Trials showing equal results for suitable patients Those results apply only to the group that was studied

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Commonly believed

Is a smaller operation always the better choice?

"The biggest operation removes the most cancer, so it is the safest."

For many early cancers, trials found that removing more tissue did not improve how the disease was controlled. It did add more lasting effects on the body. More is not automatically safer.

"Modern surgery is always small, so we should ask for the smallest."

A smaller operation only works where the evidence supports it. For some cancers, a thorough operation is still the way to remove the disease properly. Asking for less than the cancer needs can leave disease behind.

"If the doctor suggests a big operation, they must be old-fashioned."

A recommendation for a larger operation usually reflects the cancer's size, position or type. Ask why a smaller option does not suit, and what the team weighed. That is a fair question, not a challenge.

"Smaller surgery means the treatment is lighter overall."

A smaller operation often comes with radiotherapy, medicines or closer follow-up. The total treatment may take longer, even though the operation itself is less.

Where it still applies

When is radical surgery still the main option?

Radical surgery remains the main route for several cancers. Radical means removing the tumour together with a rim of healthy tissue and, often, the nearby lymph nodes. The goal is to leave no cancer behind.

Cancers where the thorough operation stays central

Cancers of the pancreas, stomach, food pipe and rectum are often treated with a planned, thorough operation, sometimes after chemotherapy or radiotherapy. Some cancers that return after radiotherapy can only be removed with a larger operation. A cancer that has grown into a neighbouring organ may need that organ removed too.

Who a smaller operation does not suit

A smaller operation is usually not suitable where the tumour is large compared with the organ, where there are several areas of cancer, or where radiotherapy has already been given to that part of the body. It may also not suit someone who cannot attend follow-up scans or daily radiotherapy.

What this means for you

Neither size is right in itself. The question to ask is what each option would mean for controlling your cancer and for your daily life afterwards.

On your report

What do the words about surgery size mean?

Radical resection
Removing the tumour with a rim of healthy tissue and often the nearby lymph nodes, aiming to leave no cancer behind.
Conservative or organ-preserving surgery
An operation that removes the cancer while keeping as much of the organ, and its function, as possible.
Sentinel node biopsy
Removing only the first lymph node or nodes the cancer drains to, to check whether it has spread.
Margin
The edge of the tissue removed. A clear margin means no cancer cells were found at that edge.
Neoadjuvant treatment
Chemotherapy or radiotherapy given before surgery, often to shrink the tumour first.

Questions we are asked

Common questions about the shift away from radical surgery

Is radical surgery outdated now?

No. It is used more selectively than before. For many early cancers a smaller operation has replaced it, but for others the thorough operation is still how the cancer is removed properly. Your team chooses based on the cancer in front of them, not on which approach sounds more modern.

Why did my relative have a bigger operation years ago for the same cancer?

Practice has changed, and the details of two cancers are rarely the same. Their cancer may have been larger, in a different position, or treated before the smaller approach was proven. Comparing the two is natural, but it is more useful to ask your own team why they are recommending what they are.

Does a smaller operation mean my cancer is less serious?

Not necessarily. It means the evidence shows a smaller operation can remove your type of cancer properly, usually with other treatment alongside. The seriousness of a cancer depends on its type, stage and behaviour, which your oncologist can explain separately from the size of the operation.

Can I ask for a smaller operation than the one offered?

You can always ask what the alternatives are and why they were not recommended. Sometimes a smaller option exists and suits you. Sometimes it would leave cancer behind. A good conversation sets out both options with their trade-offs, so you understand the recommendation rather than simply accepting or refusing it.

Will I need radiotherapy if I have the smaller operation?

Often, yes. Radiotherapy is one of the main reasons a smaller operation can work, because it deals with cancer cells that may remain nearby. Ask how many weeks of daily visits are involved and where it would be given. Travel from a district can be a real factor in the choice.

Are keyhole and robotic operations the same as less radical surgery?

No. Keyhole and robotic methods change how the surgeon reaches the tumour, through smaller cuts. They do not change how much tissue is removed. A keyhole operation can still be a fully radical one. Ask your centre which methods it uses and whether they suit your case.

Is a second opinion reasonable before a large operation?

Yes. A second opinion is a normal step before major surgery, and most surgeons expect it. Take every report, the biopsy result and the scan images on a disc. Ask the second team the same questions, so you can compare the answers clearly rather than just the recommendations.

What will a tumour board add to this decision?

At CION, cases are discussed by surgical, medical and radiation oncologists together before a plan is confirmed. That matters here, because the choice between a larger and a smaller operation often depends on what radiotherapy or chemotherapy can add. The recommendation reflects several specialties, not one view.

Meet the Specialists

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Trained at AIIMS, Tata Memorial, and leading international centres. Combined 150+ years of experience. Every complex case is reviewed by 3+ of them — together.

Dr. Naresh Gundu
Medical Oncologist

Dr. Naresh Gundu

MBBS, DNB (Internal Medicine), DM (Medical Oncology)

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Dr. C. Raghavendra Reddy
Medical Oncologist

Dr. C. Raghavendra Reddy

MBBS(Gold Medal), DNB(General Medicine), DM(Medical Oncology)(Gold Medal)

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Dr. Bharati Devi Gorantla
Medical Oncologist

Dr. Bharati Devi Gorantla

MBBS, MD(General Medicine), DM(Medical Oncology)(Adyar,Chennai), ECMO, MRCP SCE(UK)

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Dr. Owais Mohammed
Medical Oncologist

Dr. Owais Mohammed

MBBS, MD (General Medicine), DrNB (Medical Oncology), ECMO, MRCP SCE (Medical Oncology) (UK)

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Dr. T. Raghavender Reddy
Medical Oncologist

Dr. T. Raghavender Reddy

MBBS, DM (Medical Oncology), MD (Radiation Oncology)

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Dr. N. Kiranmayee
Medical Oncologist

Dr. N. Kiranmayee

MBBS, DM (Medical Oncology), MD (Internal Medicine)

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Dr. Muralidhar Muddusetty
Surgical Oncologist

Dr. Muralidhar Muddusetty

MBBS (AIIMS), MS (Surgery) (AIIMS), DNB (Surgical Oncology), MRCS (Edinburgh)

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Dr. Raghavendra Naik
Surgical Oncologist

Dr. Raghavendra Naik

MBBS, MS (General Surgery), M.Ch (Surgical Oncology)

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Dr. Mohammed  Imaduddin
Surgical Oncologist

Dr. Mohammed Imaduddin

M.B.B.S, MS (General Surgery), M.Ch (Surgical Oncology)

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Dr. Vinay Mamidala
Surgical Oncologist

Dr. Vinay Mamidala

MBBS, MS(General Surgery), M.Ch(Surgical Oncology), FMAS, FARIS(Ongoing)

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Dr. Paila Gowri Naidu
Surgical Oncologist

Dr. Paila Gowri Naidu

MBBS, MS (General Surgery), M.Ch (Surgical Oncology), FMAS

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Dr. Venkata Sushma P
Radiation Oncologist

Dr. Venkata Sushma P

MBBS, MD (Radiation Oncology)

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Dr. Kirti Ranjan Mohanty
Radiation Oncologist

Dr. Kirti Ranjan Mohanty

MBBS, MD (Radiation Oncology)

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Dr. Gangadhar Vajrala
Radiation Oncologist

Dr. Gangadhar Vajrala

MBBS, MD (Radiation Oncology), MPH

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Dr. Basudev Pokhrel
Hematologist

Dr. Basudev Pokhrel

MBBS, M.D (Immunohematology & Blood Transfusion)

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Dr. Vajja Sandeep Kumar
Surgical Oncologist

Dr. Vajja Sandeep Kumar

MBBS, MS (General Surgery), DrNB (Surgical Oncology), FALS Oncology

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Dr. Sridhar Kamani
Surgical Oncologist

Dr. Sridhar Kamani

MBBS, MS (General Surgery), DrNB (Surgical Oncology)

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Sources

  1. National Cancer Institute — Surgery to Treat Cancer
  2. Cancer Research UK — Surgery for breast cancer
  3. American Cancer Society — Cancer Surgery
  4. National Cancer Institute — Sentinel Lymph Node Biopsy

This page is general information, not a prescription. Do not change or stop any treatment based on what you read here. If anything is worrying you, contact your own treating team — or call our helpline and we will help you reach the right specialist.

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Want to understand the operation being planned?

Tell us what has been found and what has been recommended so far. We will help you reach the right surgical oncologist to talk it through. One helpline serves every CION centre.

Call 1800 202 8726

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Where to find us

Our centres in and around Hyderabad

Addressed by landmark, because that is how this city navigates. A surgical consultation can be booked at any of these centres through one helpline, and your team will tell you where the operation itself takes place.

CION Ameerpet

Beside Blue Fox Hotel, Satyam Theatre Road

Begumpet SR Nagar Punjagutta
CION Kukatpally

Opposite Big Bazaar, Mumbai Highway

KPHB JNTU Bharat Nagar
CION L.B. Nagar

Anu Arcade, next to L.B. Nagar Metro station

Vanasthalipuram Nagole Hayathnagar
CION Tolichowki

Inside Premier Hospital, Khader Bagh Road

Mehdipatnam Attapur Rethibowli
CION Masab Tank

Mahavir Hospital, AC Guards, Lakdikapul

Lakdikapul Khairatabad Basheer Bagh
CION Banjara Hills

Road No. 12

Jubilee Hills Madhapur Film Nagar
CION Kompally

Suchitra Circle, NH-44

Suchitra Circle Alwal Dundigal
CION Balanagar

Balanagar Main Road

Balanagar Fatehnagar Moosapet
CION Siddipet

Lohith Sai Hospital, Shivaji Nagar

Gajwel Husnabad Dubbaka
CION Sangareddy

X Roads, Pothreddipalle

Narayankhed Zaheerabad Patancheru
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