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Transoral laser microsurgery for the larynx | CION Cancer Clinics

Transoral laser microsurgery removes a voice box tumour through the open mouth, using a laser aimed down a microscope, with no cut on the neck. It is one of two standard treatments for early vocal cord cancer; radiotherapy is the other. This page explains what happens on the day, how recovery and the voice go afterwards, who it does not suit and what to ask. CION Cancer Clinics’ surgical oncologists in Hyderabad can talk this through with you.

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Medically reviewed by Dr. Muralidhar MuddusettyConsultant Surgical Oncologist · MBBS (AIIMS), MS (Surgery, AIIMS), DNB (Surgical Oncology), MRCS (Edinburgh) · last reviewed September 2026, next review due September 2027
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The short answer

What is transoral laser microsurgery of the larynx?

Transoral laser microsurgery, often written TLM, removes a voice box tumour through the open mouth with a laser beam aimed down a microscope. There is no cut on the neck. It is used mainly for early cancers of the vocal cords, and it is one of two standard treatments for them, the other being radiotherapy.

How the laser is used

You are fully asleep. A rigid metal tube is passed through the mouth to give a straight view of the voice box, and the microscope is lined up on it. The laser is fixed to the microscope and cuts where the surgeon aims it, sealing small blood vessels as it goes. The surgeon removes the tumour with a rim of healthy tissue, called a margin, then sends it to the laboratory.

What the operation is trying to keep

As much of the healthy vocal cord as the cancer allows. A vocal cord is a thin fold of muscle and lining. How much of it is removed decides how the voice sounds afterwards, so the surgeon takes what is needed for a clear margin and no more.

Where it is used

Which voice box cancers is laser surgery used for?

The common thread is a tumour the surgeon can see in full down the tube, and reach with a straight beam of light.

Early vocal cord cancer

The most common use. A cancer confined to one cord, with the cord still moving normally, is often removed in a single short operation with an overnight stay.

Pre-cancer on the cords

White or red patches that the biopsy calls dysplasia, meaning abnormal cells that are not yet cancer, can be shaved off with the laser to remove them and get a full sample at the same time.

Some tumours above the cords

Small cancers on the flap above the voice box, or on the folds beside it, can be reached with the laser in selected cases. These operations are larger and the stay is longer.

Where it does not suit

A tumour that has fixed the cord so it no longer moves, one that has grown into the cartilage of the voice box, or one that has spread to the front join of both cords where the laser cannot see well. Radiotherapy or open surgery is then discussed.

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On the day

What happens during the operation?

Asleep, with a special breathing tube

A general anaesthetic is used. The anaesthetist places a narrow tube, or sometimes a laser-safe tube, so the surgeon can see the cords and the laser cannot reach the airway gases.

The tube and the microscope

A rigid tube goes through the mouth and is held on a stand. The head is tilted back. This is why the lips, tongue, teeth and neck can ache afterwards. Loose teeth are protected with a guard.

The tumour is removed

Working down the microscope, the surgeon cuts around the tumour with the laser. It may come out in one piece or in several planned pieces, each labelled so the laboratory knows exactly where it sat.

Waking and going home

Most people wake with a sore throat and a hoarse or whispery voice. Eating and drinking usually start the same day. Many go home the next morning with instructions on resting the voice.

Afterwards

What does recovery look like, week by week?

  1. The first day

    Throat pain like a bad sore throat, a rough voice, sometimes a streak of blood in the spit. Cool fluids and soft food. Do not clear the throat forcefully.

  2. The first week

    Voice rest as your surgeon advises, usually meaning speak little and softly, do not whisper, do not shout. Pain settles. A follow-up camera look at the cords is arranged.

  3. The first weeks

    The raw area heals with a thin layer of new lining. The voice improves steadily but sounds breathy or rough. A speech therapist may start voice exercises once the surgeon says the cord has healed.

  4. The first months

    The final laboratory report will have come back. If the margins are clear, follow-up is a regular camera check. If not, a second laser procedure or radiotherapy is discussed at the tumour board.

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On your report

Words you will meet on the operation note

Glottis
The level of the vocal cords themselves. Supraglottis is the part above them; subglottis is the part below.
Cordectomy
Removal of part or all of a vocal cord. Reports often give a type number: a low number means a shallow shave, a high number means the whole cord and some tissue beyond it.
Anterior commissure
The front point where the two cords meet. Tumours reaching it are harder to see with the laser and are watched more closely.
Margin
The rim of normal tissue around what was removed. Clear means no cancer at the edge. Close or involved may lead to a second look or radiotherapy.
Frozen section
A quick laboratory check of an edge while you are still asleep, to guide the surgeon. The final report takes longer and is the one that counts.

Commonly believed

Three things families say about laser surgery

"Laser means the tumour is just burnt away."

The laser is a cutting tool, not a heat gun. The tumour is cut out with a margin and sent to the laboratory, exactly as with a knife. That is what allows the pathologist to say whether all of it was removed.

"He will lose his voice completely."

For an early cord cancer removed with a shallow cut, most people keep a usable voice, though it may sound rougher or breathier than before. The more of the cord that has to go, the more the voice changes. Your surgeon can tell you which type is planned.

"Choosing surgery means radiotherapy is off the table."

The opposite. One reason teams suggest laser first for an early cord cancer is that radiotherapy is kept in reserve for later if needed. Radiotherapy to the voice box is usually given once only, so using it first uses it up.

Being straight with you

What this page cannot tell you

It cannot tell you whether laser surgery is the right treatment for your cord cancer, or whether radiotherapy would serve you better. Both are standard. The choice rests on exactly where the tumour sits, whether the surgeon can get a clear view, what you use your voice for, your fitness for an anaesthetic and whether daily hospital visits for radiotherapy are possible from where you live.

What to ask your team

Ask what type of cordectomy is planned and what voice to expect from it. Ask what happens if the margins are not clear. Ask whether the surgeon does this operation regularly and how the view of your voice box looked on examination. Ask what the radiotherapy alternative would involve for you in weeks and travel.

What to tell your team

Whether you smoke, and whether you can stop before the operation, because smoke on a healing cord slows recovery. Whether you sing, teach, preach or sell for a living. Any loose teeth, dentures or neck stiffness. Every medicine you take, including blood thinners. Do not stop any medicine on your own; the surgeon and the prescribing doctor set the timing.

Questions we are asked

Common questions about laser microsurgery

Is there any cut on the neck?

No. Everything is done through the open mouth, down a rigid tube. The outside of the neck is untouched. The places that ache afterwards are the throat, the tongue, the lips and sometimes the neck muscles from the head position during the operation.

How long is the operation and the stay?

For an early cord cancer the operation itself is usually short, well under an hour, though the anaesthetic and recovery add to that. Most people stay one night and go home the next morning. Larger operations above the cords need a longer stay, which your surgeon will estimate for you.

Can he talk afterwards?

Yes, but the voice will be hoarse or whispery at first, and the surgeon will ask for voice rest for a period. That means little speech, softly, and no whispering, which strains the cords more than quiet talking. Writing notes and using a phone to type helps in the first week.

Does he need a tracheostomy?

Almost never for an early cord cancer. A temporary breathing opening in the neck is considered only for larger laser operations above the cords where swelling could narrow the airway. If your surgeon is planning one, they will say so before the day.

Will he need radiotherapy as well?

Usually not, if the final report shows clear margins. If the margins are close or involved, the options are a second laser procedure or radiotherapy, and the tumour board weighs which. Nobody can promise before the report is back, which usually takes about a week.

Is it done at CION?

What we can do straight away is read the biopsy and the camera findings and tell you whether laser surgery is worth asking about, and which questions to put to any centre. Ask any hospital how regularly the surgeon does laser cordectomy. Call the helpline and a surgical oncologist will talk it through.

Is it covered under Aarogyasri?

Cancer surgery of the voice box is generally covered under Aarogyasri, CGHS, ECHS, EHS and most cashless insurance at empanelled hospitals. Get a written estimate under your own scheme from the hospital's insurance desk before admission, and ask what, if anything, is excluded.

What can go wrong?

The common problems are a sore throat, a bruised tongue or lip, and a hoarse voice that takes weeks to settle. Less common are bleeding from the cord, swelling that narrows the airway, and scarring that leaves the voice weaker than hoped. Fresh blood in the spit or any new breathing difficulty needs same-day contact.

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Dr. Naresh Gundu

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Dr. Bharati Devi Gorantla

MBBS, MD(General Medicine), DM(Medical Oncology)(Adyar,Chennai), ECMO, MRCP SCE(UK)

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Dr. Owais Mohammed
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MBBS, MD (General Medicine), DrNB (Medical Oncology), ECMO, MRCP SCE (Medical Oncology) (UK)

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Dr. T. Raghavender Reddy
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MBBS, DM (Medical Oncology), MD (Radiation Oncology)

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Dr. N. Kiranmayee
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MBBS, DM (Medical Oncology), MD (Internal Medicine)

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Dr. Muralidhar Muddusetty
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MBBS (AIIMS), MS (Surgery) (AIIMS), DNB (Surgical Oncology), MRCS (Edinburgh)

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Dr. Raghavendra Naik
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MBBS, MS (General Surgery), M.Ch (Surgical Oncology)

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Dr. Mohammed  Imaduddin
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Dr. Vinay Mamidala
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Dr. Paila Gowri Naidu
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Dr. Venkata Sushma P
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Dr. Kirti Ranjan Mohanty
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Dr. Gangadhar Vajrala
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Dr. Basudev Pokhrel
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Dr. Vajja Sandeep Kumar
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Sources

  1. NHS — Laryngeal (larynx) cancer: treatment
  2. Cancer Research UK — Surgery for laryngeal cancer
  3. National Cancer Institute — Laryngeal Cancer Treatment (PDQ) - Patient Version
  4. American Cancer Society — Surgery for Laryngeal and Hypopharyngeal Cancers

This page is general information, not a prescription. Do not change or stop any treatment based on what you read here. If anything is worrying you, contact your own treating team — or call our helpline and we will help you reach the right specialist.

Talk to us

Been told about laser surgery for a voice box cancer?

Send us the biopsy and the camera findings or call the helpline. A surgical oncologist will explain what laser surgery would involve in your case and what to ask any centre. One helpline serves every CION centre.

Call 1800 202 8726

Speak to an oncologist

Where to find us

Our centres in and around Hyderabad

Addressed by landmark, because that is how this city navigates. A surgical consultation can be booked at any of these centres through one helpline, and your team will tell you where the operation itself takes place.

CION Ameerpet

Beside Blue Fox Hotel, Satyam Theatre Road

Begumpet SR Nagar Punjagutta
CION Kukatpally

Opposite Big Bazaar, Mumbai Highway

KPHB JNTU Bharat Nagar
CION L.B. Nagar

Anu Arcade, next to L.B. Nagar Metro station

Vanasthalipuram Nagole Hayathnagar
CION Tolichowki

Inside Premier Hospital, Khader Bagh Road

Mehdipatnam Attapur Rethibowli
CION Masab Tank

Mahavir Hospital, AC Guards, Lakdikapul

Lakdikapul Khairatabad Basheer Bagh
CION Banjara Hills

Road No. 12

Jubilee Hills Madhapur Film Nagar
CION Kompally

Suchitra Circle, NH-44

Suchitra Circle Alwal Dundigal
CION Balanagar

Balanagar Main Road

Balanagar Fatehnagar Moosapet
CION Siddipet

Lohith Sai Hospital, Shivaji Nagar

Gajwel Husnabad Dubbaka
CION Sangareddy

X Roads, Pothreddipalle

Narayankhed Zaheerabad Patancheru
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