Looking for clear, upfront core needle biopsy cost in Hyderabad? A core needle biopsy uses a slightly thicker, hollow needle to remove a small cylinder of intact tissue from a lump or organ — giving far more information than an FNAC. It is usually done under local anaesthetic with image guidance, as a day-care procedure. At CION Cancer Clinics, a core needle biopsy is performed by an oncologist or surgical oncologist and reviewed by a tumour board, so the result is complete and reliable. Your first consultation is free.
Starting from ₹7,500
The table below is an indicative guide. Your exact, confirmed price is shared once your prescription and reports are reviewed. A core needle biopsy is in the mid-range of biopsy pricing, and an ultrasound-guided core costs a little more. Histopathology, and any IHC (such as ER/PR/HER2) or molecular testing, is charged separately — see below.
| Core needle biopsy | Starting price |
|---|---|
| Core needle biopsy | ₹7,500 |
| Core needle biopsy — ultrasound-guided | ₹7,500–9,000 |
Prices shown are indicative and may vary by site, image guidance and the pathology testing required. Histopathology and any special tests (IHC / molecular) are charged separately unless stated.
A core needle biopsy is the preferred test for diagnosing a solid lump — in the breast, prostate, liver, lung or soft tissue — and whenever an FNAC has not given enough information. Because it removes intact tissue rather than loose cells, the pathologist can tell invasive cancer from non-invasive (in-situ) disease and run the tests that guide treatment.
CION Cancer Clinics offers core needle biopsy across its centres in Hyderabad, supported by a wider network of 35+ partner centres across Telangana and Andhra Pradesh — image-guided for accuracy, with indicative pricing shared up front. Because the procedure is done by a cancer specialist rather than a generic diagnostic surgeon, there is less chance of a non-diagnostic sample and a repeat biopsy. This page is part of our wider guide to Biopsy Cost in Hyderabad.
A core needle biopsy provides intact tissue, so it can distinguish invasive from in-situ cancer and allow tests such as ER, PR and HER2 and molecular profiling — information an FNAC cannot give. As the U.S. National Cancer Institute explains, the pathology report from this tissue guides the whole treatment plan.
An FNAC (fine needle aspiration) draws loose cells with a thin needle; a core biopsy removes a small cylinder of intact tissue. The intact tissue is what lets the pathologist diagnose the exact type of cancer, tell invasive from in-situ disease, and run ER/PR/HER2 and molecular tests. A core biopsy involves a local anaesthetic and costs a little more than an FNAC, and is usually preferred for a solid lump — while FNAC remains ideal for cysts, lymph nodes and confirming spread.
| Core needle biopsy | FNAC | |
|---|---|---|
| What is taken | A cylinder of intact tissue | Loose cells from the lump |
| What it can show | Exact cancer type; invasive vs in-situ; ER/PR/HER2 & molecular tests | Whether cells look benign or malignant |
| Anaesthetic | Local anaesthetic | Usually none needed |
| Best suited to | A solid lump needing full diagnosis | Cysts, lymph nodes, confirming spread |
| Relative cost | A little more | Lower |
For a fuller comparison of cytology and histopathology, see FNAC vs biopsy.
Most core biopsies are done with image guidance — ultrasound, mammography or CT — so the needle is placed precisely on the target lesion. This improves accuracy and reduces the chance of a non-diagnostic sample. To understand how the different methods are chosen, see our guide to image-guided biopsy in Hyderabad.
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Trained at AIIMS, Tata Memorial, and leading international centres. Combined 150+ years of experience. Every complex case is reviewed by 3+ of them — together.
MBBS(Gold Medal), DNB(General Medicine), DM(Medical Oncology)(Gold Medal)
MBBS, MD(General Medicine), DM(Medical Oncology)(Adyar,Chennai), ECMO, MRCP SCE(UK)
MBBS, MD (General Medicine), DrNB (Medical Oncology), ECMO, MRCP SCE (Medical Oncology) (UK)
MBBS (AIIMS), MS (Surgery) (AIIMS), DNB (Surgical Oncology), MRCS (Edinburgh)
MBBS, MS(General Surgery), M.Ch(Surgical Oncology), FMAS, FARIS(Ongoing)
MBBS, MS (General Surgery), DrNB (Surgical Oncology), FALS Oncology
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A core needle biopsy is a day-care procedure. The skin is numbed with local anaesthetic, so you feel pressure rather than sharp pain as a few small tissue cores are taken — the whole appointment is usually 15–20 minutes. You go home the same day, with mild soreness or a small bruise that settles in a day or two.
A histopathology report typically takes about 3–7 working days; if IHC or molecular tests are added, the full result takes longer. At CION, the report is reviewed by a tumour board and explained to you with a clear next step, and you are welcome to a free written second opinion on an outside report.
Core needle biopsy is used wherever a solid lump or organ lesion needs a full tissue diagnosis. A common site is the breast, where a core biopsy provides the tissue needed for ER/PR/HER2 testing — covered in detail on our breast biopsy page, which also explains vacuum-assisted breast biopsy. The same technique is used for prostate, liver, lung and soft-tissue lesions, with the method and image guidance chosen to suit the site.
For the bigger picture or a specific technique, these guides go deeper:
This page is for general information only and is not a substitute for professional medical advice, diagnosis or treatment. Biopsy prices shown are indicative and may vary by type, site, image guidance and the pathology testing required — histopathology and any special tests (such as IHC or molecular testing) are usually charged separately. Always follow the advice of a qualified doctor regarding whether a biopsy is needed and how to interpret the results.
Hear from the patients and families who came to CION for diagnosis, biopsy and cancer care — in their own words.
A core needle biopsy is in the mid-range of biopsy pricing; an ultrasound-guided core costs a little more. Histopathology and any IHC/molecular tests are separate. CION shares an indicative price once your reports are reviewed, and the first consultation is free.
FNAC samples loose cells; a core biopsy removes a cylinder of intact tissue. The intact tissue allows full typing of a cancer and tests like ER/PR/HER2, which FNAC cannot provide. A core biopsy is usually preferred for a solid lump.
It is done under local anaesthetic, so you feel pressure rather than sharp pain. The appointment is about 15-20 minutes and you go home the same day with only mild soreness.
Most do - ultrasound, mammography or CT places the needle precisely on the target, improving accuracy and reducing non-diagnostic samples.
Histopathology is usually a separate fee from the procedure, and special tests such as IHC or molecular testing add to it. We explain this clearly before you commit.
A histopathology report usually takes about 3-7 working days; if IHC or molecular tests are added, the full result takes longer. Results are reviewed by a tumour board and explained with the next step.
Yes - the intact tissue lets a pathologist confirm whether cancer is present and identify its exact type, which a scan cannot do.