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Lymphoma Diagnostics

PET-CT in Lymphoma — What It Shows

A PET-CT lymphoma scan helps your doctor see where the disease is active in your body and how well treatment is working. It combines a metabolic PET image with a detailed CT picture in one sitting. At CION, we order this scan only when it truly guides your care.

  • Accurate staging — Shows which lymph nodes and organs are involved before treatment starts.
  • Response check — Compares scans during and after therapy to see if the lymphoma is shrinking.
  • Clear results — Uses the Deauville score so your team can explain findings in plain language.
  • Free 45-minute consultation — Sit down with a doctor-led team to review your scan and plan, no rush.
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The Basics

What a PET-CT lymphoma scan actually shows

A PET-CT lymphoma scan is two scans combined into one. The PET part shows how active your cells are. The CT part shows their exact location and size. Together, they give your doctor a clear map of the disease.

Lymphoma cells use a lot of sugar to grow. Before the scan, you receive a small amount of a sugar tracer called FDG. Active lymphoma takes up more of this tracer and lights up on the images. Healthy tissue stays dim.

This is why PET-CT is so useful in lymphoma. Most Hodgkin and many aggressive non-Hodgkin lymphomas are FDG-avid, meaning they show up brightly. The scan can reveal:

Note: A few slow-growing lymphomas take up little tracer. Your doctor will tell you if PET-CT is the right tool for your type.

Did you know?

Your specialist confirms whether your lymphoma subtype is FDG-avid before recommending the scan. This is why we never order a PET-CT automatically — it is only useful when the disease takes up the tracer strongly enough to show up clearly.

Step by Step

What happens on the day of your scan

Knowing the steps ahead of time takes away most of the worry. Here is how a PET-CT lymphoma scan usually goes.

1

Preparation at home

You fast for about 6 hours before the scan. Drink only plain water. This keeps your blood sugar low so the tracer works well. Tell us if you are diabetic so we can guide you.

2

Check-in and blood sugar

A team member checks your blood sugar and weight. They explain each step and answer your questions.

3

Tracer injection

A small dose of FDG tracer is given through a vein. The needle prick is the only discomfort. The scan itself is not painful.

4

Quiet rest

You rest quietly for about 45 to 60 minutes so the tracer spreads through your body. Moving or talking too much can affect the images.

5

The scan

You lie still on a soft bed that moves slowly through the scanner. This takes roughly 20 to 30 minutes. There is no loud noise like an MRI.

6

After the scan

You can usually go home and eat normally. Drink extra water to flush out the tracer. Results are read by a specialist and discussed with your team.

Total time at the centre is often 2 to 3 hours, mostly waiting for the tracer to spread.

Not sure if you need a PET-CT?

Send us your reports. Our team reviews them in a tumour board and tells you honestly whether the scan will help, with no unnecessary tests.

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Reading Results

The Deauville score, explained simply

Doctors use the Deauville 5-point score to read how brightly lymphoma lights up on PET-CT. It compares the tracer uptake in the lymphoma to normal areas like the liver. A lower score usually means a better response.

Score What the scan shows What it often means
1 No uptake above background Complete metabolic response
2 Uptake at or below the blood pool Complete metabolic response
3 Uptake above blood pool, at or below the liver Usually a good response
4 Uptake moderately above the liver Partial response, may need closer review
5 Uptake much higher than the liver, or new spots Disease still active

Scores of 1 to 3 are generally seen as a good outcome at the end of treatment. Scores of 4 to 5 may mean your team needs to adjust the plan. Your doctor reads the score alongside your symptoms, blood tests, and full history. A single number never decides your care on its own.

We explain your Deauville score face to face, so you understand exactly what it means for you.

When It Is Used

When your doctor may order a PET-CT

A PET-CT lymphoma scan is not done randomly. It is timed to answer a specific question. At CION, every scan is discussed in our tumour board so it adds real value to your care.

At diagnosis (staging)

The scan maps where the lymphoma is in your body. This baseline is part of how blood cancer is diagnosed and helps decide how many treatment cycles you need and which areas to watch.

During treatment (interim scan)

An interim PET-CT, often after 2 cycles, shows whether the therapy is working early. A good early response can mean a gentler plan ahead. A poor response lets your team change course sooner.

After treatment (end-of-therapy scan)

This scan checks whether the lymphoma has fully responded. It guides decisions about further treatment or moving to follow-up.

If symptoms return

If signs come back later, a scan helps confirm whether the lymphoma is active again and where.

We avoid repeat scans that will not change your plan. No unnecessary tests, transparent costs, and decisions made for healing, not billing.

Routine scans for people in remission with no symptoms are usually not needed and we will tell you so.

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Common questions

PET-CT in lymphoma: your questions answered

Is a PET-CT lymphoma scan painful?

No, the scan itself is painless. The only discomfort is a small needle prick when the FDG tracer is injected into a vein, similar to a routine blood test. Once the tracer is given, you rest quietly and then lie still on a soft bed that moves slowly through the scanner. There is no loud noise and no tunnel-like tightness. Most people find it calm and easy. If you feel anxious about lying still or have claustrophobia, tell our team beforehand. We will explain each step, stay nearby, and help you feel comfortable. You deserve a scan experience that feels supportive, not stressful.

How is a PET-CT different from a normal CT scan?

A regular CT scan shows the size, shape, and location of lymph nodes and organs. It is very good at structure but cannot tell whether a lump is active lymphoma or harmless scar tissue. A PET-CT adds a second layer of information. The PET part shows how metabolically active the tissue is by using an FDG sugar tracer that lights up active lymphoma. By combining both into one scan, your doctor sees not just where something is, but whether it is alive and growing. This is especially helpful after treatment, when a leftover lump may simply be scar tissue rather than active disease.

Will the radiation from a PET-CT harm me?

A PET-CT does involve a small dose of radiation from both the tracer and the CT part. For someone with lymphoma, the benefit of accurate staging and response checking clearly outweighs this small risk. The information guides important treatment decisions and can prevent under- or over-treatment. The tracer is short-lived and leaves your body within hours, especially if you drink extra water. We follow safe-dose principles and avoid repeating scans that will not change your plan. If you are pregnant, breastfeeding, or planning pregnancy, tell us first, as we may adjust or postpone the scan. Your safety guides every decision we make.

How soon will I get my PET-CT results?

A specialist usually reads your PET-CT images within a day or two, sometimes the same day depending on the centre's workload. At CION, results are not just handed to you on paper. Your scan is reviewed and discussed with your treating team, often in our tumour board, so the findings fit into your full picture. We then explain the results to you in a 45-minute consultation, in plain language, including your Deauville score and what it means for your next step. We walk this journey with you, so you never have to interpret a confusing report alone. If anything is unclear, you can always ask for a second review.

Do I need to fast before a PET-CT lymphoma scan?

Yes, fasting is important. You should not eat for about 6 hours before the scan, though you can and should drink plain water. Avoid sugary drinks, juice, tea with sugar, and chewing gum. The reason is that the scan uses a sugar tracer. If your blood sugar is high from a recent meal, the tracer cannot work properly and the images may be hard to read. If you are diabetic, tell us in advance so we can guide your medication and meal timing safely. Avoid heavy exercise the day before, as active muscles can take up the tracer and affect the images. Our team gives you a clear preparation checklist beforehand.

Can a PET-CT tell if my lymphoma treatment is working?

Yes, this is one of its most valuable uses. By comparing a scan done during or after treatment with your baseline scan, your doctor can see whether the lymphoma is shrinking and becoming less active. An interim scan, often after two cycles of therapy, can show an early response and help decide whether your plan can stay gentle or needs to change. An end-of-treatment scan checks whether the disease has fully responded. The Deauville score puts this into a clear number. Seeing real evidence that treatment is working brings genuine reassurance. If the response is incomplete, your team can adjust the plan sooner rather than later.

What does it mean if a lump still shows on my scan after treatment?

A leftover lump after lymphoma treatment is common and often not a cause for alarm. Lymphoma can leave behind scar or fibrous tissue even after the active disease is gone. This is exactly where PET-CT helps. If the lump shows low or no tracer uptake, with a Deauville score of 1 to 3, it is usually inactive scar tissue rather than living lymphoma. If it lights up brightly, your team will look more closely and may suggest further tests or a biopsy. A scan finding is always read alongside your symptoms and blood work. Your doctor will explain clearly what your specific result means for you.

Is PET-CT useful for all types of lymphoma?

It is most useful for FDG-avid lymphomas, which take up the sugar tracer strongly. This includes most Hodgkin lymphomas and many aggressive non-Hodgkin lymphomas like diffuse large B-cell lymphoma. For these, PET-CT is excellent for staging and checking response. Some slow-growing or low-grade lymphomas take up little tracer, so PET-CT may be less helpful, and your doctor might rely more on CT or other tests. This is why we never order the scan automatically. Your specialist first considers your exact lymphoma subtype and what question needs answering. If a PET-CT will not change your treatment plan, we will tell you honestly and avoid an unnecessary test.

How much does a PET-CT lymphoma scan cost at CION?

The cost depends on the centre, the area scanned, and whether it is a baseline, interim, or follow-up scan. We believe in transparent costs, so we give you a clear estimate before anything is booked, with no hidden charges. We also only recommend a scan when it genuinely guides your care, because our decisions are made for healing, not billing. If you would like a written estimate for your situation, share your reports with us and request a cost estimation. Our team will explain what the scan involves, why it is being suggested, and exactly what you can expect to pay. You should never feel pressured into a test you do not need.

Can I drive home or go to work after the scan?

In most cases, yes. A PET-CT does not use sedation, so you stay fully awake and alert throughout. After the scan, you can usually resume normal activities, eat as usual, and return home or to work. We do ask you to drink plenty of water to help flush the tracer out of your body. The tracer's radioactivity fades quickly within a few hours. As a simple precaution, it is wise to limit close, prolonged contact with pregnant women and very young children for the rest of the day. Our team will give you clear, personalised after-care advice before you leave, so you know exactly what to do.

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