Medical Oncologist
CION Cancer Clinics
Understanding Your Genetic Test Report | CION Cancer Clinics
Plain-language guides on Understanding Your Genetic Test Report: what it means, who should be tested, what a result changes for you and your family, and where to get help in Hyderabad. Each guide is reviewed by a CION specialist. At CION Cancer Clinics in Hyderabad, our oncologists review your family history with you and guide you to the right genetic counselling and testing.
In this guide
Topics on Understanding Your Genetic Test Report
How to read a germline genetic test reportThe five classifications on a genetic test report'Pathogenic': what this word on your report means'Likely pathogenic': how sure is this result?'Variant of uncertain significance' in a germline reportWhy a VUS should not change your treatment'Benign' and 'likely benign': the two calm classificationsVariant reclassification: when a genetic result changes years laterWhat to do if you receive a genetic reclassification letterKeeping your genetic report findable for years to comeMaking sense of the c. and p. notation on your reportWhat the gene name and transcript number on your report meanHeterozygous, homozygous and compound heterozygous, explainedBiallelic findings: when both copies of a gene are affectedA negative genetic result: what it does and does not rule outUninformative negative: the genetic result nobody explainsTrue negative or uninformative negative: which one is yours?Secondary and incidental findings: results you were not looking forWhen your cancer test finds a non-cancer conditionWhen genetic testing shows an unexpected family relationshipLow-level mosaic findings on a germline genetic reportClonal haematopoiesis picked up on a genetic testWhen your genetic report says no reportable variantsWhen a genetic test fails or comes back inconclusiveWhy two labs can classify the same variant differentlyLooking up your own variant in ClinVarShould you search for your genetic variant online?Getting the raw data behind your genetic reportGetting a genetic report read again, by someone newWhat a complete genetic test report looks likeWhen a genetic report needs to be correctedGoing through a genetic report as a family
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Worried about cancer in your family?
Tell us who in the family had cancer and at what age, or what your report says. We will help you reach the right CION specialist. One helpline serves every CION centre.
