Medical Oncologist
CION Cancer Clinics
Understanding Cancer Genetics | CION Cancer Clinics
Plain-language guides on Understanding Cancer Genetics: what it means, who should be tested, what a result changes for you and your family, and where to get help in Hyderabad. Each guide is reviewed by a CION specialist. At CION Cancer Clinics in Hyderabad, our oncologists review your family history with you and guide you to the right genetic counselling and testing.
In this guide
Topics on Understanding Cancer Genetics
Cancer genetics: what it means and why it mattersAre genes the same as DNA and chromosomes?How a faulty gene leads to cancerOncogenes and tumour suppressor genesThe two-hit hypothesis, in plain EnglishDNA repair genes, and why they matter mostSporadic, familial and hereditary cancer: three different thingsWhat proportion of cancers are actually inherited?Why cancer runs in some families without a gene fault foundShared environment vs shared genes: telling the two apartDominant and recessive inheritance, explained plainlyWhy each child faces an even chance, explained simplyCan a cancer gene really skip a generation?Does it matter which parent a gene fault came from?Cancer risk from the father's side, explainedPenetrance: why carrying a gene fault is not the same as getting cancerWhy two people with the same gene fault have different outcomesModifier genes and polygenic risk, in plain languageWhat a polygenic risk score can and cannot tell youDe novo mutations: a gene fault with no family historyMosaicism explained: when a fault is in some cells, not allEpigenetics and cancer risk, explained simplyFounder mutations: why some communities share the same gene changeFounder mutations in India: what is known and what is notConsanguinity and cancer: what related parents do and do not changeEndogamy and genetic risk: what marrying within a community meansCancer genetics glossary: the words on your report, explainedCancer genetics words in Telugu, explained for the whole family
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Worried about cancer in your family?
Tell us who in the family had cancer and at what age, or what your report says. We will help you reach the right CION specialist. One helpline serves every CION centre.
