CION Cancer Clinics
Lobectomy vs sublobar resection: which, and why | CION Cancer Clinics
A lobectomy removes the whole lobe and has long been the standard operation for lung cancer confined to the lung. A sublobar operation, a segmentectomy or wedge, keeps more lung and is an accepted alternative for a small tumour near the edge, or when breathing reserve is limited. Which you are offered depends on the tumour, your lungs and what is found during surgery. This page explains what the team weighs. CION Cancer Clinics’ surgical oncologists in Hyderabad can talk this through with you.
On this page
- Lobectomy or segmentectomy: which is the right operation?
- Lobectomy and sublobar resection, compared
- What tips the decision one way or the other?
- Has segmentectomy been shown to be as good as lobectomy?
- Four things families tell us, and what is actually true
- Words you will meet when the two operations are discussed
- Common questions about lobectomy versus sublobar resection
The short answer
Lobectomy or segmentectomy: which is the right operation?
Neither is right for everyone. A lobectomy, removing the whole lobe, has long been the standard for a lung cancer confined to the lung. A sublobar operation, a segmentectomy or a wedge, is now an accepted alternative for a small tumour near the edge of the lung, and the usual choice when your breathing reserve cannot afford a lobe.
What each one trades
A lobectomy takes the widest rim of healthy tissue and every gland that drains the lobe. The price is more lost lung. A segmentectomy keeps more lung but takes a narrower rim, and if the tumour is larger or sits deep, the chance of leaving cells behind rises. The team's job is to work out, for your tumour and your lungs, which trade is the safer one.
Who a sublobar operation does not suit
It is not usually offered for a tumour that is large, central, or already known to involve the glands. In those cases the smaller operation would not clear the disease, and no amount of spared lung makes up for that.
This page explains what the team weighs. It cannot tell you which operation you should have. That comes from your scans, your breathing tests and your surgeon.Side by side
Lobectomy and sublobar resection, compared
What the team weighs
What tips the decision one way or the other?
Five things, looked at together at the tumour board. No single one decides it.
Size and position
A small tumour in the outer third of the lung is where a segmentectomy is considered. A larger one, or one near the centre where the big vessels and airways meet, points to a lobectomy.
What the nodule looks like on CT
A hazy, ground-glass nodule often grows slowly and is one of the situations where a smaller operation is favoured. A solid nodule is treated with more caution.
Your breathing reserve
Breathing tests estimate what you would be left with after each operation. If losing a lobe would leave too little, a sublobar operation or focused radiotherapy becomes the safer route.
The glands during surgery
Glands are usually sampled and examined while you are asleep. If cancer is found in them, a planned segmentectomy is often converted to a lobectomy in the same sitting.
Age and other illness
Heart disease, kidney problems or frailty change how much surgery is wise. For an older person with several conditions, keeping lung may matter more than the widest possible rim.
Ask your surgeon which of these applied to you.Not sure whether this applies to you?
Ask an oncologistWhat the studies say
Has segmentectomy been shown to be as good as lobectomy?
For one specific group, large trials in Japan and North America have compared the two operations directly. The patients had small tumours, about 2 cm or less, sitting in the outer part of the lung, with no gland involvement. In that group, segmentectomy held up well against lobectomy, and the results have changed practice.
What the trials do not say
They say nothing about larger tumours, central tumours, or tumours with involved glands, because those patients were not in the studies. A surgeon who recommends a lobectomy for a tumour outside that narrow group is following the evidence, not ignoring it. The trials also used careful gland sampling during surgery, so a segmentectomy without that step is not the operation the trials tested.
What this page cannot tell you
It cannot tell you which group you fall into, and it carries no prognosis, meaning the likely course of the illness, for either operation. Ask your surgeon whether your tumour fits the trial group, and if not, what puts it outside.
Commonly believed
Four things families tell us, and what is actually true
For a small tumour near the edge, the trials found the smaller operation held up, and it keeps lung you may need later. For a larger or central tumour, the lobe is still the safer choice. More surgery is not automatically more protection.
Sometimes it was offered because of your lungs, not your tumour. The stage comes from the pathology report after surgery. Ask which reason applied to you.
A second operation on the same lobe is harder, because of scarring, and is not always possible. That is part of why the team is cautious about who is offered a sublobar operation in the first place.
You will keep more than after a lobectomy, but any lung surgery changes your capacity, and a segment that was already scarred adds less than you might hope. The breathing tests are the honest measure of what the spared tissue is worth.
On your report
Words you will meet when the two operations are discussed
- Sublobar
- Any operation smaller than a lobectomy. Covers both segmentectomy and wedge resection.
- Peripheral
- Sitting in the outer part of the lung, away from the large vessels and airways. Where a segmentectomy is possible.
- Ground-glass opacity
- A hazy spot on CT rather than a solid lump. Often slow growing, and one of the situations where a smaller operation is considered.
- Margin
- The rim of healthy lung between the tumour and the cut edge. Wider after a lobectomy; checked during a segmentectomy.
- Frozen section
- A quick examination of glands or the cut edge while you are asleep, used to decide whether to convert to a larger operation.
- Predicted post-operative lung function
- The estimate, from your breathing tests, of what you would be left with after each operation. The number that most often decides the choice.
Questions we are asked
Common questions about lobectomy versus sublobar resection
Can I choose the smaller operation to keep more lung?
You can ask for it to be considered, and a good surgeon will explain why it is or is not suitable. Whether it is safe depends on the size and position of the tumour and on the glands. If your tumour is outside the group the trials studied, the surgeon will usually advise against it, and will say why.
Why was I offered a lobectomy when my tumour is small?
Size is only one factor. A small tumour that sits deep, near the centre, or in a position where a clean segment cannot be taken may still need the lobe. A solid nodule is also treated with more caution than a hazy one. Ask which of these applied to you.
What is a wedge, and is it the same as a segmentectomy?
No. A segmentectomy follows the lung's natural segment and takes its glands. A wedge staples out a piece around the nodule with no glands and a narrower rim. For a cancer of the lung itself, surgeons prefer a segmentectomy over a wedge where a smaller operation is being considered.
Will the surgeon decide during the operation?
Often, partly. Glands and the cut edge are examined while you are asleep, and if cancer is found the plan may change from a segmentectomy to a lobectomy in the same sitting. This should be agreed with you beforehand, so ask at consent exactly what you are agreeing to.
Is recovery quicker after a segmentectomy?
A little, mostly because air leaks tend to settle sooner and less lung surface has been cut. The cuts, the drain and the breathing exercises are the same, and most of the recovery is about the chest wall healing. Do not expect a dramatically different hospital stay.
Does a smaller operation mean less chemotherapy afterwards?
No. Whether chemotherapy or targeted tablets are recommended after surgery depends on the stage in the pathology report and the tumour's markers, not on how much lung was removed. Adjuvant treatment, meaning treatment added after surgery, is decided the same way for both operations.
What about SBRT instead of either operation?
Focused radiotherapy, called SBRT, is the usual choice when someone is not fit for any operation, and is sometimes discussed when the choice is borderline. It does not remove the tumour or the glands for examination. There is a separate page on surgery versus SBRT.
Is either operation covered by Aarogyasri or insurance?
Usually yes, when it is part of an approved cancer treatment plan. Aarogyasri, CGHS, ECHS and EHS are accepted at CION, and most cashless insurers are empanelled. Cover for keyhole charges varies between schemes, so call the helpline with your card details and we will check before you travel.
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MBBS, MD (General Medicine), DrNB (Medical Oncology), ECMO, MRCP SCE (Medical Oncology) (UK)
Dr. Muralidhar Muddusetty
MBBS (AIIMS), MS (Surgery) (AIIMS), DNB (Surgical Oncology), MRCS (Edinburgh)
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MBBS, MS(General Surgery), M.Ch(Surgical Oncology), FMAS, FARIS(Ongoing)
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MBBS, MS (General Surgery), DrNB (Surgical Oncology), FALS Oncology
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Sources
- Cancer Research UK — Surgery for lung cancer
- American Cancer Society — Surgery for Non-Small Cell Lung Cancer
- National Cancer Institute — Non-Small Cell Lung Cancer Treatment (PDQ)
- NICE — Lung cancer: diagnosis and management (NG122)
This page is general information, not a prescription. Do not change or stop any treatment based on what you read here. If anything is worrying you, contact your own treating team — or call our helpline and we will help you reach the right specialist.
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Not sure why one operation was recommended over the other?
Send us your CT report and breathing test results, or call the helpline. A surgical oncologist will explain what is planned and what the alternative would mean for you. One helpline serves every CION centre.