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Awake Brain Surgery · Hyderabad

Awake brain surgery — removing tumours near speech & movement, safely

When a tumour sits next to the areas that control your speech or movement, staying awake during part of the surgery lets the team map and protect them in real time. CION coordinates this with accredited neurosurgical partners and delivers your full cancer plan.

  • Real-time brain mapping — speech & movement areas identified and protected while you talk and move during surgery
  • Coordinated neurosurgery — surgery with accredited neurosurgical partners; molecular testing, radiation & medical therapy delivered at CION
  • Tumour board for every patient — 17 oncologists confirm surgery is the right step before you proceed
  • Transparent costs & 45-min consult — a clear written plan and estimate, with decisions made for healing, not billing
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What is awake brain surgery?

Awake brain surgery — also called an awake craniotomy — is brain tumour surgery where you stay awake for the part when the tumour is being removed. It sounds alarming, but it is one of the safest ways to take out a tumour that sits close to the areas controlling your speech or movement. The brain has no pain receptors, so the procedure does not hurt. You are kept comfortable throughout, with an anaesthetist beside you.

Being awake lets the surgical team talk with you while they work. As they map the brain surface, they ask you to name pictures, count, or move a hand. If a spot is essential for a function you rely on, they protect it. The result: more tumour removed, with your abilities kept intact. This page explains how it works, when it is needed, and how CION coordinates the surgery while delivering your wider cancer care.

Did you know?

For tumours in or near the brain's language areas, NCCN and EANO (the European Association of Neuro-Oncology) guidelines support maximal safe resection — removing as much tumour as possible without harming function. Awake mapping is a recognised way to push that safe boundary further, and studies have linked greater safe removal of gliomas to better outcomes.

When is awake surgery the right choice?

Most brain tumours are removed under general anaesthesia with a standard craniotomy. Awake surgery is reserved for tumours in eloquent brain — the areas where damage would cost speech or movement.

Tumours near speech & language

The areas that let you understand, find, and form words sit in a slightly different spot in every person. When a tumour is close to them, scans alone cannot show the exact edge. Mapping while you speak finds it precisely, so the surgeon removes tumour right up to — but not into — your language network.

Tumours near the movement (motor) area

For a tumour beside the strip of brain that controls the arm, hand, leg, or face, the team asks you to move while they stimulate the brain. This identifies the fibres that carry movement signals, so they can be protected and you keep strength on that side of the body.

When the goal is maximal safe removal

For many gliomas, removing more tumour safely can improve outcomes. Awake mapping lets the surgeon push the resection further with confidence — taking out tumour that might otherwise be left behind for fear of causing a deficit. The decision is always made first by CION's neuro-oncology tumour board.

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Meet the Specialists

17+ senior cancer specialists. One panel for your case.

Trained at AIIMS, Tata Memorial, and leading international centres. Combined 150+ years of experience. Every complex case is reviewed by 3+ of them — together.

Dr. Naresh Gundu
Medical Oncologist

Dr. Naresh Gundu

MBBS, DNB (Internal Medicine), DM (Medical Oncology)

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Dr. C. Raghavendra Reddy
Medical Oncologist

Dr. C. Raghavendra Reddy

MBBS(Gold Medal), DNB(General Medicine), DM(Medical Oncology)(Gold Medal)

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Medical Oncologist

Dr. Bharati Devi Gorantla

MBBS, MD(General Medicine), DM(Medical Oncology)(Adyar,Chennai), ECMO, MRCP SCE(UK)

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Dr. Owais Mohammed
Medical Oncologist

Dr. Owais Mohammed

MBBS, MD (General Medicine), DrNB (Medical Oncology), ECMO, MRCP SCE (Medical Oncology) (UK)

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Dr. T. Raghavender Reddy
Medical Oncologist

Dr. T. Raghavender Reddy

MBBS, DM (Medical Oncology), MD (Radiation Oncology)

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Dr. N. Kiranmayee
Medical Oncologist

Dr. N. Kiranmayee

MBBS, DM (Medical Oncology), MD (Internal Medicine)

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Dr. Muralidhar Muddusetty
Surgical Oncologist

Dr. Muralidhar Muddusetty

MBBS (AIIMS), MS (Surgery) (AIIMS), DNB (Surgical Oncology), MRCS (Edinburgh)

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Dr. Raghavendra Naik
Surgical Oncologist

Dr. Raghavendra Naik

MBBS, MS (General Surgery), M.Ch (Surgical Oncology)

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Dr. Mohammed  Imaduddin
Surgical Oncologist

Dr. Mohammed Imaduddin

M.B.B.S, MS (General Surgery), M.Ch (Surgical Oncology)

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Dr. Vinay Mamidala
Surgical Oncologist

Dr. Vinay Mamidala

MBBS, MS(General Surgery), M.Ch(Surgical Oncology), FMAS, FARIS(Ongoing)

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Dr. Paila Gowri Naidu
Surgical Oncologist

Dr. Paila Gowri Naidu

MBBS, MS (General Surgery), M.Ch (Surgical Oncology), FMAS

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Dr. Venkata Sushma P
Radiation Oncologist

Dr. Venkata Sushma P

MBBS, MD (Radiation Oncology)

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Dr. Kirti Ranjan Mohanty
Radiation Oncologist

Dr. Kirti Ranjan Mohanty

MBBS, MD (Radiation Oncology)

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Dr. Gangadhar Vajrala
Radiation Oncologist

Dr. Gangadhar Vajrala

MBBS, MD (Radiation Oncology), MPH

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Dr. Basudev Pokhrel
Hematologist

Dr. Basudev Pokhrel

MBBS, M.D (Immunohematology & Blood Transfusion)

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Dr. Mohammed Imran
Interventional Radiologist

Dr. Mohammed Imran

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Dr. Vajja Sandeep Kumar
Surgical Oncologist

Dr. Vajja Sandeep Kumar

MBBS, MS (General Surgery), DrNB (Surgical Oncology), FALS Oncology

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Dr. Sridhar Kamani
Surgical Oncologist

Dr. Sridhar Kamani

MBBS, MS (General Surgery), DrNB (Surgical Oncology)

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What happens during an awake craniotomy?

Every step is planned to keep you safe and comfortable. Here is the typical sequence, from preparation to recovery.

1 · Planning the route with functional MRI
Before surgery, a functional MRI and brain mapping scan shows where your speech and movement areas sit relative to the tumour. This map, reviewed by CION's tumour board alongside your other imaging and molecular plan, lets the surgical team plan the safest route in and decide which tasks you will perform while awake. Good planning is what makes the awake phase short and focused.
2 · Opening under sedation and scalp block
You start the operation sedated. The surgeon numbs the scalp with a local anaesthetic nerve block, then opens the scalp and a small window in the skull. Because the brain has no pain receptors and the scalp is numb, this stage is not painful. The anaesthetist controls your sedation carefully so that you are relaxed and unaware during the opening, and ready to be woken cleanly for the mapping that follows.
3 · Waking you gently for the mapping phase
Once the brain is exposed, sedation is lightened and you are gently brought to consciousness. You will be positioned comfortably and able to talk to the team. Many patients are surprised by how calm this phase feels. A speech therapist or neuropsychologist often sits with you to guide the tasks and reassure you, so you always know what is happening and what is being asked of you next.
4 · Real-time speech and movement mapping
The surgeon touches the brain surface with a tiny electrical probe while you name pictures, count, read, or move a hand or foot. If stimulating a spot briefly disrupts a function, that area is flagged as essential and protected. This is cortical and subcortical brain mapping, and it is the heart of awake surgery — it shows the live boundary between tumour that can be removed and brain that must be preserved.
5 · Removing the tumour up to safe boundaries
Guided by the live map, the surgeon removes as much tumour as can be taken safely, stopping at the functional boundaries identified during mapping. You may be asked to keep talking or moving as the resection continues, giving continuous feedback. This is how awake surgery achieves maximal safe resection — more tumour out, with your speech and movement protected throughout the operation.
6 · Re-sedation and closing the skull
When the resection is complete, sedation is deepened again and you are comfortably asleep for the skull and scalp to be closed. The bone window is secured and the scalp stitched. You will not be aware of this final stage. The tissue removed is sent straight to pathology, where histology and molecular testing begin — the results that shape the next phase of your treatment.
7 · Recovery, follow-up MRI and next steps
Most patients are awake, talking, and moving within hours, and many go home in two to four days. A short steroid course reduces swelling, and a follow-up MRI confirms how much tumour was removed. Any temporary weakness or word-finding difficulty usually improves with rehabilitation. Your CION team then sets out what follows — typically radiation and systemic therapy guided by the molecular results.

How CION coordinates your awake surgery and care

Awake brain surgery is a team effort, and the surgery is only one chapter. CION does not have an in-house neurosurgeon, so the operation itself is coordinated with accredited neurosurgical partners experienced in awake mapping. What CION delivers directly is everything that surrounds the surgery and decides the outcome:

This is why a tumour board for every patient matters: surgery, pathology, radiation, and medical oncology work as one plan, with decisions made for healing, not billing. See the complete pathway on our brain tumour treatment in Hyderabad page, or explore the full brain cancer and tumour hub.

Did you know?

Awake craniotomy is not new or experimental — it is an established technique recommended in international neuro-oncology guidance (NCCN, EANO) for tumours in eloquent brain. The brain having no pain receptors is what makes it possible to map function while you are comfortably awake.

When to get a second opinion before brain surgery

A second opinion is especially worthwhile before any brain operation. Consider asking CION's tumour board to review your case if:

You deserve a plan you understand and trust. Book a free consultation or call 18002028726 — our 45-minute consultation gives you time to ask everything, with a free written second opinion.

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Unsure if surgery is the right next step?

Before any operation, get CION's tumour board to review your scans and explain your options — including whether awake mapping is needed for your tumour's location.

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FAQs

Awake brain surgery — your questions answered

Will I feel pain during awake brain surgery?

No — awake brain surgery is not painful. The brain itself has no pain receptors, so once the scalp and skull are opened under sedation and local anaesthetic, removing the tumour does not hurt. You are gently woken only for the mapping part, and a scalp nerve block keeps the incision area numb. Most patients describe the experience as strange but comfortable, not agonising. An anaesthetist stays beside you the whole time, ready to deepen sedation if you feel anxious. After the mapping is complete, you are sedated again for the skull to be closed.

Why would a tumour need awake craniotomy instead of standard surgery?

An awake craniotomy is chosen when a tumour sits in or next to eloquent brain — the areas that control speech, language, or movement. In these locations, the surgeon cannot tell from the scan alone exactly where the function lives, because it varies slightly from person to person. By keeping you awake and asking you to talk or move during surgery, the team maps these areas in real time and works right up to their edge. This allows safe removal of more tumour while protecting the abilities that matter most to daily life. For tumours far from these areas, a standard craniotomy under general anaesthesia is usually enough.

What does brain mapping during an awake craniotomy involve?

During the awake phase, the surgeon touches the exposed brain surface with a small electrical probe while you perform tasks — naming pictures, counting, reading, or moving a hand or foot. If stimulating a spot briefly disrupts your speech or movement, that area is marked as essential and protected. This is called intra-operative cortical and subcortical mapping. It is often planned in advance with a functional MRI and brain mapping scan, which shows the likely location of speech and movement before the operation even begins, helping the team plan the safest route to the tumour.

Does CION perform awake craniotomy in-house?

CION does not have an in-house neurosurgeon, so the surgery itself is coordinated with our accredited neurosurgical partners who are experienced in awake mapping. What CION provides directly is the surrounding cancer care that determines the outcome: a multidisciplinary tumour board to confirm surgery is the right step, molecular testing on the tumour sample, radiation therapy and systemic (medical) therapy after surgery, steroid and seizure control, imaging, and rehabilitation support. We make sure surgery, pathology, radiation, and medical oncology work as one plan rather than disconnected steps.

How long does recovery take after an awake craniotomy?

Most patients are awake, talking, and moving within hours of an awake craniotomy, and many go home within two to four days if there are no complications. Because the surgery is designed to protect speech and movement, deficits are usually temporary when they occur — often improving over days to weeks with rehabilitation. A short course of steroids reduces brain swelling, and you will have a follow-up MRI to confirm how much tumour was removed. The full recovery and return-to-work timeline depends on the tumour type and what treatment follows, which your CION team will map out for you.

What treatment usually follows an awake craniotomy?

Surgery is the first step, not the whole plan. The tumour removed is sent for histology and molecular testing (markers such as IDH, MGMT, and 1p/19q), which guides what comes next. For higher-grade tumours, this typically means radiation therapy (IMRT/IGRT) and systemic therapy such as alkylating chemotherapy — both delivered directly at CION. The exact combination is decided by the tumour board. You can read more about the complete pathway on our brain tumour treatment in Hyderabad page.

Disclaimer: This content is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Awake craniotomy and other neurosurgery are coordinated with accredited neurosurgical partners; CION Cancer Clinics does not provide in-house neurosurgery. Always consult a qualified oncologist and neurosurgeon for guidance specific to your condition. This page is periodically reviewed and updated by CION's medical team in line with current NCCN and EANO guidance.

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