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Brain Metastases Care · Hyderabad

Stereotactic Radiosurgery for Brain Metastases — Focused, Brain-Sparing Radiation in 1–5 Sessions

When cancer spreads to the brain, SRS targets each lesion precisely while protecting healthy brain tissue. CION coordinates radiosurgery with the systemic care your primary cancer needs.

  • No incision, no general anaesthesia — focused radiation delivered as a same-day outpatient, most sessions under an hour
  • Brain-sparing by design — preferred over whole-brain radiation for many limited metastases, per NCCN & ASTRO guidance
  • One tumour board, both problems — radiosurgery coordinated with systemic therapy for the primary cancer
  • Free 45-minute consultation — bring your MRI and reports for a clear, transparent plan and second opinion
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Stereotactic Radiosurgery for Brain Metastases — What It Means for You

Hearing that cancer has reached the brain is frightening. But for many people with a limited number of brain metastases, treatment is precise and gentle. Stereotactic radiosurgery (SRS) delivers a high, focused dose of radiation to each lesion from many angles at once — destroying tumour cells while the healthy brain around them is largely spared.

Despite the name, radiosurgery involves no incision and no general anaesthesia. You lie still while a custom mask holds your head steady, the machine treats each target, and you usually go home the same day. Most courses finish in 1 to 5 sessions. Because the surrounding brain is protected, SRS tends to preserve memory and thinking better than older whole-brain approaches.

Brain metastases are secondary tumours — they begin in another organ and travel to the brain. That is why treating the brain alone is never the whole answer. At CION, radiosurgery is planned by our brain tumour treatment team in Hyderabad alongside systemic therapy for the cancer that started it all. For the platforms themselves, see our stereotactic radiosurgery (Gamma Knife / CyberKnife) explainer.

Did you know?

Brain metastases are more common than all primary brain tumours combined. The landmark JLGK0901 study (Yamamoto et al., Lancet Oncology, 2014) found that radiosurgery for patients with up to 10 brain metastases gave survival comparable to treating just 2 to 4 — supporting NCCN guidance that SRS is appropriate for selected patients with multiple lesions, not only one or two.

When Radiosurgery Is the Right Choice — and When It Isn't

SRS is powerful but not the only option. Your radiation oncologist weighs the number and size of lesions, your symptoms, and how well your primary cancer is controlled. Every case is reviewed by CION's tumour board before a plan is finalised.

SRS Is Often Preferred When…

You have a limited number of metastases that are not too large, each lesion is well-defined on MRI, and you want to protect memory and thinking. Modern ASTRO guidance supports SRS alone for these patients, avoiding the broader effects of whole-brain radiation. SRS is also useful for lesions in deep or risky locations and for recurrences after earlier treatment.

Whole-Brain Radiation May Be Considered When…

There are very numerous lesions, a high total tumour volume, or certain tumour types where the brain is widely involved. Whole-brain radiation treats the entire brain at once. It still has an important role, and is sometimes combined with SRS — the decision balances tumour control against quality of life, and is made individually with you.

Surgery (Coordinated) May Be Needed When…

A single large lesion is causing pressure or significant symptoms, or tissue is needed to confirm the diagnosis. Neurosurgical removal is delivered in coordination with accredited neurosurgical partners, often followed by radiosurgery to the surgical cavity. See our full guide to treatment of brain metastases.

Talk to a Radiation Oncologist About SRS

Free 45-minute consultation. Bring your MRI and reports — we'll review them and explain whether radiosurgery fits your situation.

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Meet the Specialists

17+ senior cancer specialists. One panel for your case.

Trained at AIIMS, Tata Memorial, and leading international centres. Combined 150+ years of experience. Every complex case is reviewed by 3+ of them — together.

Dr. Naresh Gundu
Medical Oncologist

Dr. Naresh Gundu

MBBS, DNB (Internal Medicine), DM (Medical Oncology)

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Dr. C. Raghavendra Reddy
Medical Oncologist

Dr. C. Raghavendra Reddy

MBBS(Gold Medal), DNB(General Medicine), DM(Medical Oncology)(Gold Medal)

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Dr. Bharati Devi Gorantla
Medical Oncologist

Dr. Bharati Devi Gorantla

MBBS, MD(General Medicine), DM(Medical Oncology)(Adyar,Chennai), ECMO, MRCP SCE(UK)

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Dr. Owais Mohammed
Medical Oncologist

Dr. Owais Mohammed

MBBS, MD (General Medicine), DrNB (Medical Oncology), ECMO, MRCP SCE (Medical Oncology) (UK)

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Dr. T. Raghavender Reddy
Medical Oncologist

Dr. T. Raghavender Reddy

MBBS, DM (Medical Oncology), MD (Radiation Oncology)

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Dr. N. Kiranmayee
Medical Oncologist

Dr. N. Kiranmayee

MBBS, DM (Medical Oncology), MD (Internal Medicine)

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Dr. Muralidhar Muddusetty
Surgical Oncologist

Dr. Muralidhar Muddusetty

MBBS (AIIMS), MS (Surgery) (AIIMS), DNB (Surgical Oncology), MRCS (Edinburgh)

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Dr. Raghavendra Naik
Surgical Oncologist

Dr. Raghavendra Naik

MBBS, MS (General Surgery), M.Ch (Surgical Oncology)

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Dr. Mohammed  Imaduddin
Surgical Oncologist

Dr. Mohammed Imaduddin

M.B.B.S, MS (General Surgery), M.Ch (Surgical Oncology)

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Dr. Vinay Mamidala
Surgical Oncologist

Dr. Vinay Mamidala

MBBS, MS(General Surgery), M.Ch(Surgical Oncology), FMAS, FARIS(Ongoing)

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Dr. Paila Gowri Naidu
Surgical Oncologist

Dr. Paila Gowri Naidu

MBBS, MS (General Surgery), M.Ch (Surgical Oncology), FMAS

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Dr. Venkata Sushma P
Radiation Oncologist

Dr. Venkata Sushma P

MBBS, MD (Radiation Oncology)

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Dr. Kirti Ranjan Mohanty
Radiation Oncologist

Dr. Kirti Ranjan Mohanty

MBBS, MD (Radiation Oncology)

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Dr. Gangadhar Vajrala
Radiation Oncologist

Dr. Gangadhar Vajrala

MBBS, MD (Radiation Oncology), MPH

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Dr. Basudev Pokhrel
Hematologist

Dr. Basudev Pokhrel

MBBS, M.D (Immunohematology & Blood Transfusion)

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Dr. Mohammed Imran
Interventional Radiologist

Dr. Mohammed Imran

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Dr. Vajja Sandeep Kumar
Surgical Oncologist

Dr. Vajja Sandeep Kumar

MBBS, MS (General Surgery), DrNB (Surgical Oncology), FALS Oncology

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Dr. Sridhar Kamani
Surgical Oncologist

Dr. Sridhar Kamani

MBBS, MS (General Surgery), DrNB (Surgical Oncology)

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Want a specific doctor for your case? Mention them when booking.

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Talk to a Specialist About Radiosurgery Today

Whether SRS, surgery, or whole-brain radiation is right for you depends on your scan and your primary cancer. Our tumour board reviews every case — and the consultation is free.

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How Radiosurgery Is Planned and Delivered

SRS only works because it is precise. The planning is as important as the treatment itself. Here is the pathway at CION, from scan to follow-up.

  1. 1
    High-resolution MRI with contrast — the gold standard for finding and measuring each brain metastasis. The number, size, and location of lesions guide whether SRS, surgery, or whole-brain radiation fits best.
  2. 2
    Tumour board review — your radiation oncologist, medical oncologist, and coordinated neurosurgical input agree the plan together, taking into account how well your primary cancer is controlled.
  3. 3
    Immobilisation and planning scan — a custom mask (or frame) keeps your head perfectly still. A planning CT is fused with your MRI so the dose is shaped tightly around each lesion.
  4. 4
    Treatment delivery — most sessions take under an hour. You are awake, lying still; there is no cutting and no pain from the radiation itself. SRS is delivered as part of coordinated radiosurgery care, on the platform best suited to your lesions.
  5. 5
    Follow-up MRI every 2–3 months — to confirm the lesions are shrinking and catch any new ones early. Systemic therapy for your primary cancer continues throughout.

Ready to review your scan? Book a free consultation or call 18002028726 — bring your MRI and primary-cancer reports.

Gamma Knife, CyberKnife, and Linac SRS — What's the Difference?

Patients often search for "gamma knife brain mets" and worry they need a specific machine. In truth, these are platforms that all deliver stereotactic radiosurgery. The skill of the planning team matters more than the brand name.

The right platform depends on the size, number, and position of your lesions. CION delivers radiosurgery as part of coordinated specialist care and helps you reach the most suitable option — we do not claim an in-house Gamma Knife or proton unit, and we will always be transparent about where each part of your care is delivered.

What CION Delivers Directly — and What We Coordinate

Brain metastases need more than one treatment. CION provides the medical and supportive backbone directly, and coordinates the rest with accredited partners — so your care stays joined-up.

Delivered Directly at CION

  • Imaging and diagnosis, including MRI review
  • Radiation therapy planning — IMRT and IGRT
  • Systemic therapy for the primary cancer driving the metastases
  • Steroid management to reduce brain swelling
  • Seizure (antiepileptic) management
  • Supportive, rehab, and quality-of-life care

Coordinated With Accredited Partners

  • Stereotactic radiosurgery delivery (Gamma Knife / CyberKnife / linac SRS)
  • Neurosurgical resection of a large or symptomatic single lesion
  • Stereotactic biopsy where tissue confirmation is needed
  • Whole-brain radiation where it is the better option

CION's oncology panel does not include an in-house neurosurgeon; neurosurgery is always coordinated with accredited neurosurgical partners.

Get a Free Radiosurgery Plan Review

Share your MRI and primary-cancer reports — we'll tell you whether SRS, surgery, or whole-brain radiation is the right next step. Free written second opinion.

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Brain Metastases Start Somewhere Else — Treat Both

Because brain metastases are secondary tumours, controlling the original cancer is part of every plan. Radiosurgery clears the brain lesions; systemic therapy keeps the source in check. Some metastases even respond to modern immunotherapy or targeted therapy given for the primary cancer. Explore care for the cancers that most often spread to the brain:

When to Seek a Second Opinion

A second opinion is especially worthwhile if you have a limited number of brain metastases and have been offered whole-brain radiation without any discussion of SRS, or if no one has explained how your primary-cancer treatment connects to the brain plan. CION offers a free written second opinion from a tumour board that reviews both problems together.

Did you know?

Modern EANO–ESMO and ASTRO guidance favour stereotactic radiosurgery over whole-brain radiation for many patients with a limited number of brain metastases, because trials show better preservation of memory and thinking with similar control of the treated lesions. The right approach is always individual — your scan and overall condition decide.

Second Opinion Available

Been Offered Whole-Brain Radiation Without SRS?

If radiosurgery wasn't discussed for a limited number of brain metastases, a free written second opinion from CION's tumour board is worth it — SRS often preserves cognition better.

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Surgery, Chemo & Radiation Done by Dr. Imaduddin, Dr. Vinay, Dr. Owais, Dr. Kirti

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Successful Radical Thymectomy Done by Dr. Mohammed Imaduddin & Dr. Vinay Mamidala

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Successful Surgery Done by Dr. Rajender Byshetty

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Successful Chemo & Surgery Done by Dr. Imad, Dr. Vinay, Dr. Owais & Dr. Raghavendra

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Successful Chemo & Surgery Done by Dr. Imad, Dr. Vinay, Dr. Owais & Dr. Raghavendra

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Successful Chemo & Radiation Done by Dr. Owais Mohammed & Dr. Kirti Ranjan Mohanty

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Successful Breast Cancer Surgery Done by Dr. Imaduddin Mohammed & Dr. Vinay Mamidala

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Successful Chemotherapy Done by Dr. Bharati Devi Gorantla

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Successful Chemo & Surgery Done by Dr. Owais Mohammed & Dr. Imaduddin Mohammed

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Successful Chemotherapy Done by Dr. Gundu Naresh

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FAQs

SRS for Brain Metastases — Your Questions Answered

What is stereotactic radiosurgery (SRS) for brain metastases?

Stereotactic radiosurgery is a non-invasive radiation treatment that delivers a high, precisely focused dose to each brain metastasis from many angles at once. Despite the word "surgery", there is no incision and no general anaesthesia. The healthy brain around the lesion receives very little radiation, which helps protect memory and thinking. SRS is usually completed in 1 to 5 outpatient sessions. According to NCCN and ASTRO guidance, SRS is the preferred option for many patients with a limited number of brain metastases, instead of whole-brain radiation.

How is SRS different from Gamma Knife or CyberKnife?

Gamma Knife and CyberKnife are brand names for two machines that deliver stereotactic radiosurgery — they are platforms, not different treatments. Gamma Knife uses many cobalt sources focused on the target; CyberKnife uses a robotic arm with a linear accelerator. Modern linac-based SRS can also treat brain metastases precisely. The right platform depends on lesion size, number, and location. At CION, radiosurgery is delivered as part of coordinated specialist care, and our radiation oncology team helps you choose the most suitable approach. Learn more on our stereotactic radiosurgery explainer.

How many brain metastases can be treated with radiosurgery?

There is no single fixed limit. For years, SRS was reserved for 1 to 4 lesions, but published evidence — including the JLGK0901 study and current NCCN guidance — supports radiosurgery for selected patients with more lesions, sometimes 10 or more. What matters most is the total tumour volume, the size of each lesion, your symptoms, and how well your primary cancer is controlled. Your radiation oncologist reviews your MRI and overall condition to decide whether SRS, surgery, whole-brain radiation, or a combination fits best. See treatment of brain metastases for the full picture.

Is SRS better than whole-brain radiation therapy?

For many patients with a limited number of metastases, SRS is preferred because it spares healthy brain tissue and is linked to better preservation of memory and thinking than whole-brain radiation therapy (WBRT). Randomised trials and ASTRO guidance support SRS alone for these patients. WBRT still has a role — for example, with very numerous lesions or certain tumour types. The decision is individual, balancing tumour control against quality of life. CION reviews every case in a tumour board so the recommendation fits your situation, not a one-size-fits-all rule.

What happens during and after an SRS session?

You lie still while a custom mask or frame holds your head steady, and the machine delivers focused radiation — most sessions take under an hour and you go home the same day. There is no cutting and usually no recovery period. Some people feel mild tiredness or a short-lived headache. Your team monitors response with follow-up MRI scans, typically every 2 to 3 months. Occasionally a treated lesion can swell temporarily (radiation effect) and needs steroids; this is managed by your oncologist. Book a free consultation to discuss what your sessions would involve.

Does CION have a Gamma Knife or proton machine in-house?

CION delivers radiation therapy including IMRT and IGRT directly, and arranges stereotactic radiosurgery as part of coordinated specialist care with accredited radiosurgery and neurosurgical partners. We do not claim an in-house Gamma Knife or proton unit. What we do directly is just as important: molecular and imaging diagnosis, planning your radiation, systemic therapy for the primary cancer driving the metastases, steroid and seizure management, and supportive care — all coordinated by one tumour board so nothing falls through the cracks.

Which cancers most often spread to the brain?

Brain metastases are secondary tumours — they start somewhere else and travel to the brain. The most common sources are lung cancer, breast cancer, melanoma (skin cancer), and kidney cancer. Because the original cancer keeps driving the disease, treating the brain lesions with radiosurgery is only part of the plan — systemic therapy for the primary cancer continues alongside. CION coordinates both so your brain and your primary cancer are treated as one connected problem.

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