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Brain Tumour Care · Hyderabad

Brain Tumour Surgery — What to Expect, Step by Step

If surgery has been suggested for your brain tumour, the unknown is the hardest part. This guide explains the operation, recovery and what comes next — in plain language.

  • Coordinated neurosurgery — operations done with accredited neurosurgical partners; before-and-after care managed by CION
  • Molecular testing standard — IDH & MGMT arranged on the surgical sample to guide what comes next
  • Tumour board for every patient — surgery, radiation and medical oncology plan your case together
  • 45-minute consultation — transparent costs and a free written second opinion before you decide
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Why Surgery Is Often the First Step

For most brain tumours that can be safely reached, surgery is the first treatment. It does two important jobs at once: it removes as much of the tumour as can be safely taken out, and it gives the team a tissue sample to confirm exactly what kind of tumour it is. That sample is then sent for molecular testing — the results often decide what treatment, if any, is needed afterwards.

The amount of tumour removed — called the extent of resection — is one of the strongest factors linked to better outcomes for high-grade tumours. That is why the goal is always maximal safe resection: taking out as much tumour as possible while protecting the parts of the brain that control speech, movement, vision and memory.

Not every tumour needs surgery. Some small, slow-growing or benign tumours are simply watched with regular scans. Some deep tumours are reached only by a needle biopsy. Your team weighs the tumour's location, size and type against the risks before recommending an operation — and this is reviewed at a multidisciplinary tumour board.

Did you know?

The brain itself has no pain receptors. That is why an awake craniotomy is possible — once the scalp and skull are opened under local anaesthetic, the brain can be operated on while the patient is awake and talking, with no pain. The European Association of Neuro-Oncology (EANO) and NCCN guidelines support awake mapping for tumours in or near the brain areas that control speech and movement, because it lets the surgeon remove more tumour while protecting these functions.

When Is Brain Tumour Surgery Recommended?

Surgery is usually considered when one or more of the following is true:

Where a tumour is too deep or too close to critical areas for open surgery, a stereotactic needle biopsy or focused radiation may be chosen instead. The right path is always a balance between benefit and risk — discussed openly with you. Book a free consultation to understand which applies to your tumour.

Types of Brain Tumour Surgery — Explained Simply

"Brain surgery" is not one operation. The approach is chosen to match where the tumour sits, how big it is, and what the team needs to achieve. Here are the main types you may hear about. At CION, all of these neurosurgical procedures are coordinated with accredited neurosurgical partners, while the imaging, planning, molecular testing and follow-on care are delivered by CION.

Craniotomy — the standard tumour removal operation

A craniotomy is the most common brain tumour operation. The surgeon removes a small section of skull to reach the tumour, removes as much as can be safely taken out, then replaces the bone and closes the scalp. Neuronavigation — a real-time map built from your MRI — guides the surgeon to the exact tumour location and away from critical structures. A craniotomy usually takes 3 to 6 hours under general anaesthetic. It is the right choice for most tumours that can be safely reached. Read more about craniotomy for a brain tumour and what it involves.

Awake craniotomy — surgery with mapping for speech and movement

When a tumour sits in or near the areas controlling speech, language or movement, an awake craniotomy can remove more tumour while protecting these functions. The skull is opened under sedation and local anaesthetic; because the brain feels no pain, the patient is then gently woken and asked to talk, name objects or move a hand while the surgeon maps which areas are doing what. The tumour is removed while responses are watched in real time, so the surgeon knows exactly where to stop. The patient is sedated again for closure. EANO and NCCN guidelines support awake mapping for tumours in these "eloquent" areas.

Stereotactic needle biopsy — diagnosis without open surgery

For tumours that are deep, small, or in locations too risky for open removal, a stereotactic biopsy takes a tiny tissue sample using a fine needle guided by imaging — without opening the skull widely. It does not remove the tumour, but it confirms the exact diagnosis and provides tissue for the molecular testing (IDH, MGMT) that guides treatment. It is a much smaller procedure than a craniotomy, often with an overnight stay. The team chooses biopsy first when removing the tumour would carry too much risk before the diagnosis is known.

Endoscopic and transsphenoidal approaches — reaching the tumour through a natural route

Some tumours — particularly pituitary tumours at the base of the brain — can be reached through the nose using an endoscope, avoiding a skull opening altogether. This is called an endoscopic transsphenoidal approach. Recovery is usually quicker than open surgery, and there is no visible scar. Whether this route is possible depends entirely on the tumour's location and type. These specialist approaches are delivered through CION's coordinated neurosurgical partners.

Debulking and partial removal — when full removal is not safe

Sometimes a tumour cannot be fully removed because it wraps around critical structures or spreads into healthy brain. In these cases the surgeon performs a debulking — removing as much as is safely possible to relieve pressure and reduce the tumour burden. This can ease symptoms and make follow-on radiation or systemic therapy more effective. Partial removal is a deliberate, planned decision that puts your safety and function first, not a failed operation.

Shunt placement and pressure relief — managing fluid build-up

Some brain tumours block the normal flow of cerebrospinal fluid, causing a dangerous build-up of pressure called hydrocephalus. A small tube called a shunt can be placed to drain the fluid and relieve symptoms such as severe headache, drowsiness and vomiting. This may be done before, during or after tumour surgery depending on the situation. Like other neurosurgical procedures, shunt placement is coordinated with CION's accredited neurosurgical partners, while CION manages the surrounding care.

Important: the right operation for you depends on a careful review of your scans and diagnosis. This page explains the options — your brain tumour treatment team will recommend the one that fits your tumour.

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Meet the Specialists

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Trained at AIIMS, Tata Memorial, and leading international centres. Combined 150+ years of experience. Every complex case is reviewed by 3+ of them — together.

Dr. Naresh Gundu
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Dr. Naresh Gundu

MBBS, DNB (Internal Medicine), DM (Medical Oncology)

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Medical Oncologist

Dr. C. Raghavendra Reddy

MBBS(Gold Medal), DNB(General Medicine), DM(Medical Oncology)(Gold Medal)

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Medical Oncologist

Dr. Bharati Devi Gorantla

MBBS, MD(General Medicine), DM(Medical Oncology)(Adyar,Chennai), ECMO, MRCP SCE(UK)

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Medical Oncologist

Dr. Owais Mohammed

MBBS, MD (General Medicine), DrNB (Medical Oncology), ECMO, MRCP SCE (Medical Oncology) (UK)

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Dr. T. Raghavender Reddy
Medical Oncologist

Dr. T. Raghavender Reddy

MBBS, DM (Medical Oncology), MD (Radiation Oncology)

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Dr. N. Kiranmayee
Medical Oncologist

Dr. N. Kiranmayee

MBBS, DM (Medical Oncology), MD (Internal Medicine)

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Dr. Muralidhar Muddusetty

MBBS (AIIMS), MS (Surgery) (AIIMS), DNB (Surgical Oncology), MRCS (Edinburgh)

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Dr. Raghavendra Naik
Surgical Oncologist

Dr. Raghavendra Naik

MBBS, MS (General Surgery), M.Ch (Surgical Oncology)

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Dr. Mohammed  Imaduddin
Surgical Oncologist

Dr. Mohammed Imaduddin

M.B.B.S, MS (General Surgery), M.Ch (Surgical Oncology)

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Dr. Vinay Mamidala
Surgical Oncologist

Dr. Vinay Mamidala

MBBS, MS(General Surgery), M.Ch(Surgical Oncology), FMAS, FARIS(Ongoing)

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Dr. Paila Gowri Naidu
Surgical Oncologist

Dr. Paila Gowri Naidu

MBBS, MS (General Surgery), M.Ch (Surgical Oncology), FMAS

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Dr. Venkata Sushma P
Radiation Oncologist

Dr. Venkata Sushma P

MBBS, MD (Radiation Oncology)

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Dr. Kirti Ranjan Mohanty
Radiation Oncologist

Dr. Kirti Ranjan Mohanty

MBBS, MD (Radiation Oncology)

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Dr. Gangadhar Vajrala
Radiation Oncologist

Dr. Gangadhar Vajrala

MBBS, MD (Radiation Oncology), MPH

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Dr. Basudev Pokhrel
Hematologist

Dr. Basudev Pokhrel

MBBS, M.D (Immunohematology & Blood Transfusion)

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Dr. Mohammed Imran
Interventional Radiologist

Dr. Mohammed Imran

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Dr. Vajja Sandeep Kumar
Surgical Oncologist

Dr. Vajja Sandeep Kumar

MBBS, MS (General Surgery), DrNB (Surgical Oncology), FALS Oncology

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Dr. Sridhar Kamani
Surgical Oncologist

Dr. Sridhar Kamani

MBBS, MS (General Surgery), DrNB (Surgical Oncology)

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Before Surgery — How You'll Be Prepared

Good preparation makes surgery safer and recovery smoother. In the days before your operation, your team will arrange:

It helps to bring a family member, a list of your current medicines, and a written list of questions. A free 45-minute consultation is the right time to ask exactly what your operation involves.

What Happens During the Operation

  1. 1
    Anaesthetic and positioning — most craniotomies are done under general anaesthetic. Your head is gently fixed in position and the area is prepared. For an awake craniotomy, sedation and local anaesthetic are used for the opening.
  2. 2
    Reaching the tumour — a small section of skull is removed and set aside. Neuronavigation guides the surgeon to the tumour while avoiding critical structures. If the tumour is near speech or movement areas, awake mapping is used.
  3. 3
    Removing the tumour — as much tumour as can be safely removed is taken out (maximal safe resection). Samples are sent for diagnosis and molecular testing.
  4. 4
    Closing up — the bone is replaced and secured, and the scalp is closed. You are moved to intensive care for close monitoring as you wake up.

A typical craniotomy takes 3 to 6 hours, though this varies with the tumour's size and location.

Recovery After Brain Tumour Surgery

Recovery is gradual, and the timeline depends on the tumour's location, the type of surgery, and your general health. A common pattern looks like this:

A follow-up MRI is usually done within a couple of days of surgery to check how much tumour was removed, and again later to plan any treatment that follows.

Understanding the Risks

All brain surgery carries risk, and being informed helps you make the right decision with your team. The main risks include:

Your surgical team will explain the risks that apply to your exact tumour before you consent. The whole approach is built around maximal safe resection — never removing tumour at the cost of vital function.

Did you know?

Surgery is rarely the end of the story. The tissue removed during your operation is sent for molecular testing — markers such as IDH mutation and MGMT methylation. NCCN guidelines use these results to decide whether radiation and systemic therapy are needed and which approach works best. This is why a surgical sample, even from a partial removal, is so valuable: it shapes every treatment decision that follows.

What Treatment Follows Surgery?

Surgery removes the tumour and gives the diagnosis — but for many tumours it is the first step, not the only one. What comes next depends on the tumour grade and the molecular test results:

CION delivers the radiation therapy, systemic therapy, steroid and seizure management, and supportive care that follow surgery directly — all coordinated through a tumour board that reviews every case. Explore the full brain tumour treatment pathway or read about the craniotomy procedure in detail.

Get a Free Review Before Your Surgery

Bring your MRI, biopsy report and any molecular test results — we'll review them and explain your safest surgical option. Free written second opinion.

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When to Get a Second Opinion Before Surgery

Brain surgery is a major decision, and a second opinion is especially worthwhile in these situations:

CION offers a free written second opinion reviewed by a neuro-oncology tumour board. We walk this journey with you — with transparent costs and decisions made for healing, not billing. Request your free review or call 18002028726.

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Want a Second Opinion Before You Operate?

A free written review of your imaging and plan — especially valuable if awake mapping or molecular testing has not yet been discussed for your tumour.

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FAQs

Brain Tumour Surgery — Your Questions Answered

What happens during brain tumour surgery?

The most common operation is a craniotomy — the surgeon removes a small section of skull, takes out as much tumour as can be safely removed, then replaces the bone. A real-time imaging guide called neuronavigation shows the team exactly where the tumour sits and where critical brain areas are. Most operations take 3 to 6 hours. The brain itself feels no pain, so for tumours near speech or movement areas an awake craniotomy may be used. At CION, neurosurgery is delivered in coordination with accredited neurosurgical partners, while our oncology team plans the imaging, molecular testing and the treatment that follows.

How long is recovery after a brain tumour operation?

Most people spend 1 to 2 days in intensive care for close monitoring, then a few more days on the ward — a typical hospital stay is 3 to 7 days. You may feel tired, have a headache, or notice some swelling for a couple of weeks. Many people return to light daily activities within 4 to 6 weeks, though full recovery depends on the tumour location, the type of surgery, and whether radiation or chemotherapy follows. Driving, work and exercise are reintroduced gradually with your team's guidance. Rehabilitation — physiotherapy, speech therapy or cognitive support — is arranged when needed.

Is brain surgery for a tumour dangerous?

All brain surgery carries risk, but modern techniques have made it far safer than in the past. The main risks are bleeding, infection, swelling, seizures, and temporary or lasting changes to speech, movement or vision — depending on where the tumour sits. Neuronavigation, intra-operative imaging and awake mapping are used specifically to protect critical brain areas. Your surgical team will explain the risks that apply to your exact tumour before you decide. The goal is always maximal safe resection — removing as much tumour as possible without harming healthy function.

Will I need treatment after brain tumour surgery?

Often, yes. Surgery removes the bulk of the tumour and provides tissue for a definitive diagnosis, but the surgical sample is sent for molecular testing (such as IDH and MGMT) that guides what comes next. For high-grade tumours, radiation therapy and chemotherapy usually follow a few weeks later. Benign Grade 1 tumours that are fully removed may need no further treatment — just monitoring scans. CION delivers the radiation therapy (IMRT/IGRT), systemic therapy and supportive care that follow surgery, and reviews every case at a multidisciplinary tumour board.

What is the difference between a biopsy and tumour removal surgery?

A biopsy takes only a small tissue sample to confirm the diagnosis and tumour type — it does not remove the tumour. A stereotactic needle biopsy uses imaging to guide a fine needle to a deep or risky tumour without opening the skull widely. A resection (craniotomy) aims to remove as much of the tumour as is safely possible. Sometimes a biopsy is done first to plan treatment when the tumour is in a delicate location; sometimes biopsy and removal happen in the same operation. Your team decides based on the tumour's location, size and the imaging findings.

Does CION have a neurosurgeon in-house?

CION's panel is led by medical and radiation oncologists. The neurosurgery itself — craniotomy, awake craniotomy, stereotactic biopsy and related procedures — is coordinated with accredited neurosurgical partners. CION delivers everything around the operation directly: advanced imaging and diagnosis, molecular testing on the tumour sample, radiation therapy (IMRT/IGRT), systemic therapy, steroid and seizure management, and rehabilitation. This means your whole journey — before and after surgery — is planned and managed by one coordinated team, with a tumour board reviewing every case.

How do I prepare for brain tumour surgery?

Your team will arrange pre-operative scans (usually an MRI with contrast), blood tests and an anaesthetic review. You may be asked to stop certain medicines — especially blood thinners — and to fast for several hours beforehand. Steroids are often started to reduce brain swelling, and anti-seizure medicine may be prescribed. It helps to bring a family member, list your current medicines, and write down your questions. A free consultation at CION is a good time to understand exactly what your operation involves and what recovery will look like for you.

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