CION Cancer Clinics
Turnaround times for genetic tests, by test type | CION Cancer Clinics
The narrower the test, the faster the answer. A test for one fault already known in the family is usually the quickest, a multigene panel takes longer, and reading every gene takes longest of all. This page compares the main test types, explains where the time goes inside the laboratory, and shows what speeds a result up or holds it back. At CION Cancer Clinics in Hyderabad, our oncologists review your family history with you and guide you to the right genetic counselling and testing.
On this page
- Why do some genetic tests come back faster than others?
- How long does each kind of genetic test usually take?
- What happens between the sample arriving and the report?
- The timing words you will meet, in plain language
- What speeds a result up, and what slows it down?
- What this page cannot tell you
- Four things families assume about the wait
- Common questions about how long genetic tests take
The short answer
Why do some genetic tests come back faster than others?
The narrower the question, the faster the answer. A test for one fault already known in the family is usually the quickest. A panel of many genes takes longer, and a test of every gene takes longer still. Most inherited cancer tests are measured in weeks rather than days, and your laboratory can give you its own expected date when the sample is sent.
Where the time actually goes
Drawing the blood takes minutes. The wait is spent in the laboratory, where the DNA is extracted, read and then checked by a scientist who decides what each difference means. The reading is largely done by machines. The checking is done by people, and it is the part that grows with every extra gene on the list.
Why the fastest test is not always the right one
A quicker test that asks the wrong question only delays the real answer. Your counsellor chooses the test that fits your family history, then tells you honestly how long it is likely to take. If a treatment decision is waiting on the result, say so at the start. Laboratories can often prioritise a sample when a surgery date or a medicine choice depends on it.
A slow result is not a sign of bad news. It usually means more genes, more checking, or a queue.Test by test
How long does each kind of genetic test usually take?
These are relative, not promises. Each laboratory publishes its own expected time for each test it runs.
A known family fault
The laboratory looks at one spot in one gene, because a relative's fault has already been found. This is usually the quickest inherited test there is.
Needs
- A copy of the relative's report
- The exact variant named on it
A small targeted test
A handful of genes linked to one cancer, such as a test limited to the two BRCA genes. It is faster than a wide panel, though slower than a known-fault test.
A multigene panel
Dozens of genes read together. This is the commonest first test for someone who has had cancer. More genes mean more differences to classify, and more chance of one needing a second look.
Exome, genome or a tissue block
Reading every gene, or working from old stored tissue, takes the longest. These are rarely the first test in cancer genetics, and a tissue block adds the time needed to retrieve it from the hospital that holds it.
Not sure whether this applies to you?
Ask an oncologistInside the laboratory
What happens between the sample arriving and the report?
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The sample is checked in
Labels are matched to the forms and consent. A missing signature or a spelling mismatch stops the clock here until it is fixed.
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DNA is extracted
The DNA is separated from the rest of the blood or saliva and its quality is measured. A poor sample may need to be drawn again.
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The genes are read
Sequencing machines usually run samples in batches. A laboratory waits until a batch is full, which is one reason timing varies.
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Each difference is classified
A scientist compares every difference found against published evidence and shared databases, and decides whether it is harmful, harmless or uncertain. This is the slowest human step.
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Important findings are confirmed
A harmful result is often rechecked by a second method before it is reported. Some panels also need a separate test for larger missing or extra pieces of a gene.
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The report is signed and sent
A senior scientist signs it off and the report goes to the doctor or counsellor who ordered it, who then books time to explain it.
On the paperwork
The timing words you will meet, in plain language
- Turnaround time
- The laboratory's expected time from receiving the sample to releasing the report. Courier time and the result appointment come on top.
- Urgent or priority request
- A request, usually from the treating doctor, to move a sample up the queue because treatment depends on the answer.
- Batch
- A group of samples run through the sequencing machine together. Your sample waits until its batch is ready.
- Confirmation testing
- A second, different test used to check a harmful finding before it is reported.
- Deletion and duplication testing
- A check for whole missing or extra pieces of a gene, which standard reading can miss. It is sometimes run separately.
- Variant of uncertain significance
- A difference the laboratory cannot yet call harmful or harmless. Classifying it carefully can add time to the report.
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Side by side
What speeds a result up, and what slows it down?
Being straight with you
What this page cannot tell you
It cannot give you a date for your own result. Turnaround depends on the laboratory, the test chosen and how busy the laboratory is that month. The expected date printed on your request form, or given by the laboratory when it logs your sample, is more accurate than any general guide.
It cannot tell you what a delay means
A result that runs late is usually paperwork, a full queue or a routine confirmation step. It says nothing about what the report will contain. Reading meaning into a delay causes worry it rarely deserves. What your specific result means is a question for the counsellor who ordered the test.
Who this does not apply to
Most people do not need an inherited cancer test at all, so for most families the wait never arises. This page is also about inherited testing on blood or saliva. Tests on the tumour itself, used to choose treatment, follow a different route and timetable, covered under targeted therapy.
If your expected date has passed, ask the laboratory or the counsellor for an update. It is a normal question to ask.Commonly believed
Four things families assume about the wait
Timing reflects the test and the queue far more than the finding. A clear normal panel can take as long as one with a harmful result, because every gene still has to be checked.
Some laboratories offer a priority service, but the classification step cannot be rushed without losing care. A priority request is best kept for when treatment truly depends on the answer.
It may be quicker, because you are likely to be tested only for the fault already found in the family. It may equally take longer, if your own history points to a wider test.
The laboratory's clock starts when the sample arrives and passes its checks. Courier time, and any delay over missing paperwork, comes before that point.
Questions we are asked
Common questions about how long genetic tests take
Which genetic test gives the quickest result?
A test for a single fault already found in a relative. The laboratory knows exactly where to look, so there is far less to read and classify. This is why relatives are usually tested after, not alongside, the person who has had cancer.
Can the result be hurried if surgery is waiting on it?
Often, yes. Ask your surgeon or oncologist to mark the request as urgent and to explain why. Many laboratories prioritise samples when a treatment decision depends on the answer, though the checking steps still take their time.
Why does a panel take longer than a single-gene test?
Every gene on the panel has to be read and every difference found has to be classified by a scientist. More genes mean more differences, and more chance that one needs confirming or a careful second review before the report is signed.
Does sending the sample abroad add time?
Usually, yes. International courier and customs add time at both ends, and paperwork problems are harder to fix from a distance. Many inherited cancer tests are now done by laboratories in India, which your counsellor can help you compare.
Does a stored tissue block take longer than blood?
Generally, yes. The block first has to be found and released by the hospital that holds it, and DNA from old stored tissue is often harder to read. It is still worth it when the relative who had cancer has died.
Will an uncertain finding delay my report?
It can add a little time while the laboratory reviews the evidence. An uncertain finding is not a positive result and should not change your care. Ask how you will be told if it is ever reclassified in the future.
What should I do if the expected date has passed?
Contact the laboratory or the counsellor who ordered the test and ask where the sample is. Have the patient's name, date of birth and sample number ready. A short delay is common and rarely means anything about the result.
Who can tell me how long my own test will take?
The laboratory running it, or the counsellor who ordered it. If you are not sure which laboratory has your sample, call the CION helpline and someone will help you find out where it is and when to expect the report.
Meet CION's oncologists. Bring your family history or genetic report to them.
Our medical oncologists see people with a strong family history of cancer, arrange genetic counselling and testing where it fits, and plan the checks that follow.
Dr. C. Raghavendra Reddy
MBBS(Gold Medal), DNB(General Medicine), DM(Medical Oncology)(Gold Medal)
Dr. Bharati Devi Gorantla
MBBS, MD(General Medicine), DM(Medical Oncology)(Adyar,Chennai), ECMO, MRCP SCE(UK)
Dr. Owais Mohammed
MBBS, MD (General Medicine), DrNB (Medical Oncology), ECMO, MRCP SCE (Medical Oncology) (UK)
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Sources
- MedlinePlus Genetics — What is the cost of genetic testing, and how long does it take to get the results?
- National Cancer Institute — Genetic Testing for Inherited Cancer Susceptibility Syndromes
- MedlinePlus Genetics — What do the results of genetic tests mean?
- NHS — Predictive genetic tests for cancer risk genes
This page is general information, not a prescription. Do not change or stop any treatment based on what you read here. If anything is worrying you, contact your own treating team — or call our helpline and we will help you reach the right specialist.
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Is a treatment decision waiting on a genetic result?
Tell us which test was sent and when. We will help you find out where the sample is and whether it can be prioritised. One helpline serves every CION centre.