Medically reviewed by Dr. Muralidhar Muddusetty, Surgical Oncologist · Last reviewed June 2026.
Salivary gland cancers are uncommon and behave in many different ways, so the right treatment is rarely the same for two people. At CION Cancer Clinics, every plan is decided by a multidisciplinary tumor board — surgical, radiation, and medical oncologists together — so the treatment fits you, not a template.
Salivary gland cancers can start in the parotid, submandibular, sublingual, or smaller minor salivary glands, and they range from slow-growing to aggressive. For most patients, surgery to remove the tumour is the main treatment, often followed by radiation. Systemic therapy may be added for advanced disease. The right combination depends on the tumour type, its grade, its location, and your overall health — which is why CION reviews every case at a tumor board rather than relying on a single opinion.
Your oncologist will explain which oral cancer treatment options are recommended for you, in what order, and what to expect — in a 45-minute consultation with no rushed decisions and no unnecessary tests at our oral cancer hospital in Hyderabad.
*1-year survival: CION oral cancer patients 80.0% vs national average 71.6% (Δ +8.4 points). Source: ICMR / National Cancer Registry Programme (NCRP).
Salivary gland cancers make up only about 3–5% of all head and neck cancers, and the parotid gland is the most common site (American Cancer Society). Because they are uncommon and vary so widely, treatment at a centre with a multidisciplinary tumor board matters.
The main treatment for most salivary gland cancers — for example parotidectomy or removal of the submandibular gland, with care taken to protect nearby facial nerves whenever possible.
Often given after surgery for higher-grade or advanced tumours to lower the chance of the cancer returning, or as a main treatment when surgery is not suitable.
Chemotherapy or targeted therapy may be used for advanced, recurrent, or metastatic disease, guided by the tumour type and current guidelines.
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Trained at AIIMS, Tata Memorial, and leading international centres. Combined 150+ years of experience. Every complex case is reviewed by 3+ of them — together.
MBBS(Gold Medal), DNB(General Medicine), DM(Medical Oncology)(Gold Medal)
MBBS, MD(General Medicine), DM(Medical Oncology)(Adyar,Chennai), ECMO, MRCP SCE(UK)
MBBS, MD (General Medicine), DrNB (Medical Oncology), ECMO, MRCP SCE (Medical Oncology) (UK)
MBBS (AIIMS), MS (Surgery) (AIIMS), DNB (Surgical Oncology), MRCS (Edinburgh)
MBBS, MS(General Surgery), M.Ch(Surgical Oncology), FMAS, FARIS(Ongoing)
MBBS, MS (General Surgery), DrNB (Surgical Oncology), FALS Oncology
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Talk to a CION oncologist about your salivary gland cancer treatment — decisions for healing, not billing.
The exact operation depends on which gland is involved and how far the tumour has spread. Your surgical oncologist will explain the procedure and its likely effects before anything begins.
Removal of part or all of the parotid gland, the most common site. Care is taken to identify and protect the facial nerve wherever the tumour allows.
Removal of the affected submandibular gland, sometimes with nearby tissue, depending on the tumour type and grade.
Removal of neck lymph nodes when the cancer has spread or is high-grade, to check and control disease in the neck.
From your first visit to recovery, CION pairs treatment with allied care — healing beyond medicine — so you are supported at every stage.
Hear from patients treated across the CION network, then book a free consultation to discuss your own plan.
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Start Your Story. Book Free Consultation.For most patients, surgery to remove the tumour is the main treatment. Depending on the tumour type, grade, and stage, radiation is often given after surgery, and systemic therapy may be added for advanced disease. At CION, a tumor board of surgical, radiation, and medical oncologists decides the right combination and sequence for you, and explains the reasoning in a 45-minute consultation.
Parotid surgery is performed close to the facial nerve, so protecting it is a priority whenever the tumour allows. Your surgical oncologist will explain the specific risks for your tumour, including any temporary or lasting effect on facial movement, before you decide. Where nerve function is affected, rehabilitation and reconstruction options are discussed as part of your care.
Not always. Radiation is usually recommended for higher-grade tumours, larger tumours, positive margins, or when cancer has reached the lymph nodes. For low-grade tumours removed completely, surgery alone may be enough. The tumor board reviews your pathology before recommending radiation, so the decision is based on your specific results, not a fixed rule.
Chemotherapy and targeted therapy are used mainly for advanced, recurrent, or metastatic salivary gland cancer rather than as a first treatment. The choice depends on the tumour type and current guidelines. Your medical oncologist will explain whether systemic therapy is appropriate for you and what benefits and side effects to expect.
Cost depends on the type of surgery, whether radiation or systemic therapy is needed, and your hospital stay. CION provides a clear cost estimate before treatment begins, avoids unnecessary tests, and helps coordinate insurance. Request a free consultation for an estimate specific to your treatment plan.
Yes. A free written second opinion is included with your first consultation. Share your reports and a senior oncologist will review your diagnosis and treatment options. There is no commitment to start treatment at CION — the goal is to help you make an informed decision.
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