NCCN-protocol oral cancer care · Multidisciplinary tumour board · ArogyaSri, CGHS & cashless insurance accepted · Free second opinion
1800 202 8726
Oral Cancer Care · Medical Oncology · Hyderabad

Chemotherapy for Oral Cancer — Planned by a Tumor Board, Not One Doctor

Medically reviewed by Dr. Naresh Gundu, Medical Oncologist · Last reviewed June 2026.

Chemotherapy is one part of oral cancer care — used before surgery, alongside radiation, or for advanced disease. At CION Cancer Clinics, every chemotherapy plan is decided by a multidisciplinary tumor board so the treatment fits you, not a template.

  • Tumor board for every patient — your chemotherapy plan is reviewed by medical, surgical, and radiation oncologists together.
  • 45-minute consultation — no rushed decisions; we explain why each drug is or isn't recommended for you.
  • Transparent costs — clear estimates before you start, with no unnecessary tests.
  • 35+ centres across Telangana & AP — care close to home, supported by 17 super-specialist oncologists.
4.8 · 800+ Google reviews · 15,000+ patients treated
Limited Slots Today

Discuss Your Chemotherapy Options

₹950   Today: FREE  ·  Including free written second opinion

Reviewed by a senior medical oncologist
Free written second opinion
Confidential. No commitment to start treatment.
or
Call 18002028726
17
Super-specialist
Oncologists
80.0%
Oral Cancer 1-yr
Survival at CION*
15,000+
Patients
Treated
4.8★
Google Rating
(800+ reviews)

*1-year survival rate for oral cancer patients at CION Cancer Clinics (80.0%) vs the national average (71.6%) reported by ICMR / National Cancer Registry Programme (NCRP).

Understanding the role of chemotherapy

Where Chemotherapy Fits in Oral Cancer Treatment

Oral cancer is rarely treated with chemotherapy alone. For most patients, surgery and radiation are the main treatments, and chemotherapy is added to make those treatments work better or to control disease that has spread. The right combination depends on the stage of the cancer, where it is in the mouth, and your overall health — which is exactly why CION reviews every case at a tumor board rather than relying on a single opinion.

Your medical oncologist will explain why chemotherapy is or isn't part of your plan, how many cycles are expected, and what side effects to watch for — in a 45-minute consultation with no rushed decisions and no unnecessary tests.

Did you know?

India accounts for roughly one-third of the world's oral cancer cases, driven largely by tobacco and areca-nut use (ICMR / National Cancer Registry Programme). When chemotherapy is used, it is most often combined with radiation or surgery rather than given on its own.

How it is given

Ways Chemotherapy Is Used for Oral Cancer

Concurrent chemoradiation

Chemotherapy (commonly cisplatin) given at the same time as radiation. The drug makes cancer cells more sensitive to radiation, improving local control for advanced or high-risk disease.

Neoadjuvant (before surgery)

Chemotherapy given before surgery to shrink a large tumour, in selected cases, so that surgery can be more complete and function better preserved.

For advanced or recurrent disease

When oral cancer has spread or returned, chemotherapy — sometimes with targeted therapy or immunotherapy — is used to control the disease and ease symptoms.

Get a Free Second Opinion on Your Treatment Plan

Share your reports and a senior medical oncologist will review whether chemotherapy is right for you — at no cost.

or
Call 18002028726

By submitting, you consent to be contacted by CION about your enquiry.

12+ Centres in Hyderabad · Pick yours

CION cancer care is closer than you think.

We're never more than 30 minutes away. Same panel of specialists at every centre. Same tumour board reviews. Same NCCN protocols. Pick the closest one and call directly — or let us pick for you.

Not sure which centre fits best? Tell us where you are — we'll suggest the closest one with the right specialists.

Help me pick the right centre
Beyond Hyderabad

35+ centres across Telangana & Andhra Pradesh

Travelling for treatment? We may have a centre right where you are.

Don't see your city? Call 18002028726 — we'll find your nearest CION partner centre.

Meet the Specialists

17+ senior cancer specialists. One panel for your case.

Trained at AIIMS, Tata Memorial, and leading international centres. Combined 150+ years of experience. Every complex case is reviewed by 3+ of them — together.

Dr. Naresh Gundu
Medical Oncologist

Dr. Naresh Gundu

MBBS, DNB (Internal Medicine), DM (Medical Oncology)

View Profile
Dr. C. Raghavendra Reddy
Medical Oncologist

Dr. C. Raghavendra Reddy

MBBS(Gold Medal), DNB(General Medicine), DM(Medical Oncology)(Gold Medal)

View Profile
Dr. Bharati Devi Gorantla
Medical Oncologist

Dr. Bharati Devi Gorantla

MBBS, MD(General Medicine), DM(Medical Oncology)(Adyar,Chennai), ECMO, MRCP SCE(UK)

View Profile
Dr. Owais Mohammed
Medical Oncologist

Dr. Owais Mohammed

MBBS, MD (General Medicine), DrNB (Medical Oncology), ECMO, MRCP SCE (Medical Oncology) (UK)

View Profile
Dr. T. Raghavender Reddy
Medical Oncologist

Dr. T. Raghavender Reddy

MBBS, DM (Medical Oncology), MD (Radiation Oncology)

View Profile
Dr. N. Kiranmayee
Medical Oncologist

Dr. N. Kiranmayee

MBBS, DM (Medical Oncology), MD (Internal Medicine)

View Profile
Dr. Muralidhar Muddusetty
Surgical Oncologist

Dr. Muralidhar Muddusetty

MBBS (AIIMS), MS (Surgery) (AIIMS), DNB (Surgical Oncology), MRCS (Edinburgh)

View Profile
Dr. Raghavendra Naik
Surgical Oncologist

Dr. Raghavendra Naik

MBBS, MS (General Surgery), M.Ch (Surgical Oncology)

View Profile
Dr. Mohammed  Imaduddin
Surgical Oncologist

Dr. Mohammed Imaduddin

M.B.B.S, MS (General Surgery), M.Ch (Surgical Oncology)

View Profile
Dr. Vinay Mamidala
Surgical Oncologist

Dr. Vinay Mamidala

MBBS, MS(General Surgery), M.Ch(Surgical Oncology), FMAS, FARIS(Ongoing)

View Profile
Dr. Paila Gowri Naidu
Surgical Oncologist

Dr. Paila Gowri Naidu

MBBS, MS (General Surgery), M.Ch (Surgical Oncology), FMAS

View Profile
Dr. Venkata Sushma P
Radiation Oncologist

Dr. Venkata Sushma P

MBBS, MD (Radiation Oncology)

View Profile
Dr. Kirti Ranjan Mohanty
Radiation Oncologist

Dr. Kirti Ranjan Mohanty

MBBS, MD (Radiation Oncology)

View Profile
Dr. Gangadhar Vajrala
Radiation Oncologist

Dr. Gangadhar Vajrala

MBBS, MD (Radiation Oncology), MPH

View Profile
Dr. Basudev Pokhrel
Hematologist

Dr. Basudev Pokhrel

MBBS, M.D (Immunohematology & Blood Transfusion)

View Profile
Dr. Mohammed Imran
Interventional Radiologist

Dr. Mohammed Imran

View Profile
Dr. Vajja Sandeep Kumar
Surgical Oncologist

Dr. Vajja Sandeep Kumar

MBBS, MS (General Surgery), DrNB (Surgical Oncology), FALS Oncology

View Profile
Dr. Sridhar Kamani
Surgical Oncologist

Dr. Sridhar Kamani

MBBS, MS (General Surgery), DrNB (Surgical Oncology)

View Profile

Want a specific doctor for your case? Mention them when booking.

Book Free Consultation

You deserve a plan built around you

Talk to a CION medical oncologist about whether chemotherapy fits your oral cancer treatment — decisions for healing, not billing.

Book Free Consultation Call 18002028726
Drugs and combinations

Chemotherapy and Systemic Options We Use

The exact drugs are chosen by your tumor board based on stage, prior treatment, and your general health. Your oncologist will discuss benefits and side effects before anything begins.

Chemotherapy

Cisplatin-based chemotherapy

A platinum drug used most often, given alone or with radiation. Used in concurrent chemoradiation and in advanced disease combinations.

Targeted therapy

Cetuximab (EGFR-targeted)

A targeted drug that may be combined with chemotherapy or radiation in selected patients, depending on the tumour and prior treatment.

Immunotherapy

Pembrolizumab

An immunotherapy option for recurrent or metastatic disease in eligible patients, used per current guidelines and biomarker testing.

Talk to a specialist

Ask Whether Chemotherapy Is Right for You

or
Call 18002028726
Supportive care

How We Help You Manage Side Effects

Chemotherapy affects everyone differently. At our oral cancer hospital in Hyderabad, CION pairs treatment with allied care — healing beyond medicine — so side effects are managed early.

  1. Nutrition support — a nutritionist helps you keep weight and strength up; CION patients see notably less treatment-related weight loss.
  2. Mouth and symptom care — early management of mouth soreness, nausea, and fatigue so cycles stay on schedule.
  3. Psycho-oncology support — emotional support for you and your family throughout treatment.
Real patients, real journeys

We walk this journey with you

Hear from patients treated across the CION network, then book a free consultation to discuss your own plan.

Book Free Consultation Call 18002028726
Real Stories. Real Voices.

15,000+ patients chose CION. Hear from them directly.

These aren't paid endorsements or written reviews. These are video testimonials from real patients and families — recorded on their own phones, in their own words. Pick any one. Watch it. Then decide.

4.8★800+ Google reviews
50+video testimonials
15,000+patients treated
Successful Chemotherapy Done by Dr. C Raghavendra Reddy

Successful Chemotherapy Done by Dr. C Raghavendra Reddy

Watch video →
Surgery, Chemo & Radiation Done by  Dr. Imaduddin, Dr. Vinay, Dr. Owais, Dr. Kirti

Surgery, Chemo & Radiation Done by Dr. Imaduddin, Dr. Vinay, Dr. Owais, Dr. Kirti

Watch video →
 Successful Radical Thymectomy Done by  Dr. Mohammed Imaduddin & Dr. Vinay Mamidala

Successful Radical Thymectomy Done by Dr. Mohammed Imaduddin & Dr. Vinay Mamidala

Watch video →
Successful Surgery Done  by Dr. Rajender Byshetty

Successful Surgery Done by Dr. Rajender Byshetty

Watch video →
Successful Chemo & Surgery Done by  Dr. Imad, Dr. Vinay, Dr. Owais & Dr. Raghavendra

Successful Chemo & Surgery Done by Dr. Imad, Dr. Vinay, Dr. Owais & Dr. Raghavendra

Watch video →
Successful Chemo & Surgery Done by  Dr. Imad, Dr. Vinay, Dr. Owais & Dr. Raghavendra

Successful Chemo & Surgery Done by Dr. Imad, Dr. Vinay, Dr. Owais & Dr. Raghavendra

Watch video →
Successful Chemo & Radiation Done by Dr. Owais Mohammed & Dr. Kirti Ranjan Mohanty

Successful Chemo & Radiation Done by Dr. Owais Mohammed & Dr. Kirti Ranjan Mohanty

Watch video →
Successful Breast Cancer Surgery Done by Dr. Imaduddin Mohammed & Dr. Vinay Mamidala

Successful Breast Cancer Surgery Done by Dr. Imaduddin Mohammed & Dr. Vinay Mamidala

Watch video →
Successful Chemotherapy Done by Dr. Bharati Devi Gorantla

Successful Chemotherapy Done by Dr. Bharati Devi Gorantla

Watch video →
Successful Chemo & Surgery Done by Dr. Owais Mohammed & Dr. Imaduddin Mohammed

Successful Chemo & Surgery Done by Dr. Owais Mohammed & Dr. Imaduddin Mohammed

Watch video →
Successful Chemotherapy Done by Dr. Gundu Naresh

Successful Chemotherapy Done by Dr. Gundu Naresh

Watch video →
Successful Bone Marrow Transplantation - Neuroblastoma

Successful Bone Marrow Transplantation - Neuroblastoma

Watch video →
Successful Surgery & Chemo - Carcinoma of Caecum

Successful Surgery & Chemo - Carcinoma of Caecum

Watch video →
Successful Oral chemotherapy & mastectomy surgery

Successful Oral chemotherapy & mastectomy surgery

Watch video →
Successful Oral chemotherapy & mastectomy surgery

Successful Oral chemotherapy & mastectomy surgery

Watch video →
Successful Chemotherapy

Successful Chemotherapy

Watch video →
Successful Surgery by Dr. Mohammed Imaduddin

Successful Surgery by Dr. Mohammed Imaduddin

Watch video →
Successful Bone Marrow Transplantation

Successful Bone Marrow Transplantation

Watch video →
Successful Oral chemotherapy & mastectomy surgery

Successful Oral chemotherapy & mastectomy surgery

Watch video →
Successful Oral chemotherapy & mastectomy surgery

Successful Oral chemotherapy & mastectomy surgery

Watch video →
Successful Chemotherapy

Successful Chemotherapy

Watch video →
Successful Buccal Mucosa Surgery

Successful Buccal Mucosa Surgery

Watch video →
Successful Complex Surgery Mandibulectomy Reconstruction

Successful Complex Surgery Mandibulectomy Reconstruction

Watch video →
Common questions

Chemotherapy for Oral Cancer — Common Questions

Is chemotherapy always needed for oral cancer?

No. Many oral cancers are treated mainly with surgery and radiation. Chemotherapy is added in specific situations — such as concurrent chemoradiation for advanced disease, before surgery in selected cases, or for cancer that has spread or returned. At CION, a tumor board decides whether chemotherapy is right for your stage and overall health, and your oncologist explains the reasoning in a 45-minute consultation.

What is concurrent chemoradiation?

Concurrent chemoradiation means giving chemotherapy and radiation at the same time. The chemotherapy drug — most commonly cisplatin — makes cancer cells more sensitive to radiation, which can improve local control of advanced or high-risk oral cancer. Your team monitors you closely during this period to manage side effects and keep treatment on schedule.

Which chemotherapy drugs are used for oral cancer?

Cisplatin is the most commonly used chemotherapy drug. Depending on the situation, your oncologist may also use targeted therapy such as cetuximab, or immunotherapy such as pembrolizumab for recurrent or metastatic disease in eligible patients. The exact choice is made by the tumor board based on stage, prior treatment, biomarker testing, and your general health.

What side effects can I expect, and how are they managed?

Common effects include nausea, fatigue, mouth soreness, and reduced appetite. CION pairs treatment with allied care — a nutritionist to protect your weight and strength, supportive medicines for symptoms, and psycho-oncology support for you and your family. Managing side effects early helps keep your cycles on schedule.

How much does chemotherapy for oral cancer cost?

Cost depends on the drugs, number of cycles, and whether chemotherapy is combined with radiation or surgery. CION provides a clear cost estimate before you start, avoids unnecessary tests, and helps coordinate insurance. Request a free consultation for an estimate specific to your treatment plan.

Can I get a second opinion before starting chemotherapy?

Yes. A free written second opinion is included with your first consultation. Share your reports and a senior medical oncologist will review whether chemotherapy — and which approach — is appropriate for you. There is no commitment to start treatment at CION.

Call now Book free consultation