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UNDERSTANDING MOUTH CANCER

Mouth Cancer — know the signs early

Medically reviewed by Dr. Muralidhar Muddusetty, Surgical Oncologist · Last reviewed June 2026

Mouth cancer, also called oral cancer, can begin as a sore, patch or lump that does not heal. Spotted early, it is highly treatable. At CION Cancer Clinics, a tumor board of medical, surgical and radiation oncologists plans your care together — no rushed decisions, no unnecessary tests.

  • Tumor board for every patient — not one doctor's opinion
  • 45-minute consultation — time to understand your diagnosis
  • Transparent costs — decisions for healing, not billing
  • 35+ centres — care close to home across Telangana & AP
4.8 · 800+ Google reviews · 15,000+ patients treated
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17
Super-Specialist
Oncologists
35+
Centres Across
Telangana & AP
15,000+
Patients
Treated
4.8★
Google Rating
(4.8/5)
What it is

What is mouth cancer?

Mouth cancer — also known as oral cancer — is a cancer that grows in the tissues of the mouth. It can start in the lips, gums, tongue, the inner lining of the cheeks, the roof of the mouth or the floor of the mouth. Most mouth cancers are squamous cell carcinomas, which begin in the thin, flat cells that line these surfaces.

It often starts as a small change that does not heal — a sore, a red or white patch, or a lump. Because the mouth is easy to see and feel, many of these changes can be noticed early. Found early, mouth cancer is highly treatable. Any change that lasts longer than two to three weeks deserves a check-up with a doctor or dentist.

Did you know?

India accounts for roughly one-third of the world's oral cancer cases, driven largely by chewing tobacco, gutkha and betel quid (areca nut). Because the mouth is easy to examine, most of these cancers can be caught at an early, more treatable stage. Source: ICMR / National Cancer Registry Programme.

Early signs

Signs and symptoms to watch for

None of these always mean cancer — but if any lasts more than two to three weeks, get it checked.

Causes & risk factors

What raises the risk of mouth cancer?

Most mouth cancers are linked to lifestyle factors you can change. Avoiding these is the most effective way to lower your risk.

Highest risk

Tobacco in any form

Smoking, gutkha, khaini, zarda and paan masala all sharply raise the risk. Smokeless tobacco held against the cheek or gum is especially harmful.

Common in India

Betel quid & areca nut

Chewing paan with areca nut (supari), with or without tobacco, is a major cause of mouth cancer across South Asia.

Adds to risk

Heavy alcohol use

Alcohol raises the risk on its own. Used together with tobacco, the two multiply the risk well beyond either alone.

Other factors

HPV, sun & diet

Certain HPV infections, prolonged sun exposure to the lips, and a diet low in fruits and vegetables can also contribute.

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Meet the Specialists

17+ senior cancer specialists. One panel for your case.

Trained at AIIMS, Tata Memorial, and leading international centres. Combined 150+ years of experience. Every complex case is reviewed by 3+ of them — together.

Dr. Naresh Gundu
Medical Oncologist

Dr. Naresh Gundu

MBBS, DNB (Internal Medicine), DM (Medical Oncology)

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Dr. C. Raghavendra Reddy
Medical Oncologist

Dr. C. Raghavendra Reddy

MBBS(Gold Medal), DNB(General Medicine), DM(Medical Oncology)(Gold Medal)

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Dr. Bharati Devi Gorantla
Medical Oncologist

Dr. Bharati Devi Gorantla

MBBS, MD(General Medicine), DM(Medical Oncology)(Adyar,Chennai), ECMO, MRCP SCE(UK)

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Dr. Owais Mohammed
Medical Oncologist

Dr. Owais Mohammed

MBBS, MD (General Medicine), DrNB (Medical Oncology), ECMO, MRCP SCE (Medical Oncology) (UK)

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Dr. T. Raghavender Reddy
Medical Oncologist

Dr. T. Raghavender Reddy

MBBS, DM (Medical Oncology), MD (Radiation Oncology)

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Dr. N. Kiranmayee
Medical Oncologist

Dr. N. Kiranmayee

MBBS, DM (Medical Oncology), MD (Internal Medicine)

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Dr. Muralidhar Muddusetty
Surgical Oncologist

Dr. Muralidhar Muddusetty

MBBS (AIIMS), MS (Surgery) (AIIMS), DNB (Surgical Oncology), MRCS (Edinburgh)

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Dr. Raghavendra Naik
Surgical Oncologist

Dr. Raghavendra Naik

MBBS, MS (General Surgery), M.Ch (Surgical Oncology)

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Dr. Mohammed  Imaduddin
Surgical Oncologist

Dr. Mohammed Imaduddin

M.B.B.S, MS (General Surgery), M.Ch (Surgical Oncology)

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Dr. Vinay Mamidala
Surgical Oncologist

Dr. Vinay Mamidala

MBBS, MS(General Surgery), M.Ch(Surgical Oncology), FMAS, FARIS(Ongoing)

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Dr. Paila Gowri Naidu
Surgical Oncologist

Dr. Paila Gowri Naidu

MBBS, MS (General Surgery), M.Ch (Surgical Oncology), FMAS

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Dr. Venkata Sushma P
Radiation Oncologist

Dr. Venkata Sushma P

MBBS, MD (Radiation Oncology)

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Dr. Kirti Ranjan Mohanty
Radiation Oncologist

Dr. Kirti Ranjan Mohanty

MBBS, MD (Radiation Oncology)

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Dr. Gangadhar Vajrala
Radiation Oncologist

Dr. Gangadhar Vajrala

MBBS, MD (Radiation Oncology), MPH

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Dr. Basudev Pokhrel
Hematologist

Dr. Basudev Pokhrel

MBBS, M.D (Immunohematology & Blood Transfusion)

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Dr. Mohammed Imran
Interventional Radiologist

Dr. Mohammed Imran

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Dr. Vajja Sandeep Kumar
Surgical Oncologist

Dr. Vajja Sandeep Kumar

MBBS, MS (General Surgery), DrNB (Surgical Oncology), FALS Oncology

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Dr. Sridhar Kamani
Surgical Oncologist

Dr. Sridhar Kamani

MBBS, MS (General Surgery), DrNB (Surgical Oncology)

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Want a specific doctor for your case? Mention them when booking.

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Meet the team that will walk this journey with you

Medical, surgical and radiation oncologists plan every mouth cancer case together. Book a free consultation to discuss your diagnosis.

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Diagnosis

How mouth cancer is diagnosed

Getting the diagnosis right matters. Each step builds a clear, evidence-based picture before any treatment begins.

  1. 1

    Examination

    A doctor examines the mouth, lips, tongue and neck, looking for sores, patches, lumps or swollen lymph nodes.

  2. 2

    Biopsy

    A small tissue sample is taken from the suspicious area. A pathologist examines it under a microscope to confirm whether cancer is present and what type it is.

  3. 3

    Imaging & staging

    Scans such as CT, MRI or PET-CT show the size of the tumour and whether it has spread to lymph nodes or beyond. This is how the stage is determined.

  4. 4

    Tumor board review

    At CION, findings are discussed by a tumor board of specialists so a single, agreed treatment plan is made — not one doctor's opinion.

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Treatment

How mouth cancer is treated

Treatment depends on the stage and location. Often two or more approaches are combined, and care is planned by a team.

Surgery

Removing the tumour and, where needed, affected lymph nodes. Reconstruction can restore appearance and function.

Radiation therapy

Targeted high-energy beams destroy cancer cells, used alone or alongside surgery and chemotherapy.

Chemotherapy & targeted therapy

Medicines that treat cancer throughout the body, often combined with radiation for advanced cases.

Rehabilitation & allied care

Speech, swallowing and nutrition support, plus psycho-oncology — healing beyond medicine.

Outcomes

Oral cancer survival at CION vs national average

Early detection and team-led, evidence-based care improve outcomes.

Cancer CION National average
Oral cancer 80.0% 71.6%

*1-year survival. Source: ICMR / National Cancer Registry Programme (NCRP).

You are not alone

Hear from patients we have walked beside

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Real Stories. Real Voices.

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Successful Chemotherapy Done by Dr. C Raghavendra Reddy

Successful Chemotherapy Done by Dr. C Raghavendra Reddy

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Surgery, Chemo & Radiation Done by  Dr. Imaduddin, Dr. Vinay, Dr. Owais, Dr. Kirti

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 Successful Radical Thymectomy Done by  Dr. Mohammed Imaduddin & Dr. Vinay Mamidala

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Successful Oral chemotherapy & mastectomy surgery

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Successful Oral chemotherapy & mastectomy surgery

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Successful Complex Surgery Mandibulectomy Reconstruction

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Common questions

Mouth cancer — your questions answered

What is mouth cancer?

Mouth cancer, also called oral cancer, is a cancer that develops in the tissues of the mouth. It can begin in the lips, gums, tongue, the inner lining of the cheeks, the roof of the mouth, or the floor of the mouth. Most mouth cancers are squamous cell carcinomas, which start in the flat cells lining these surfaces. Finding it early gives the best chance of successful treatment, so any change that does not heal within two to three weeks should be checked by a doctor.

What are the early signs of mouth cancer?

Common early signs include a mouth ulcer or sore that does not heal within two to three weeks, a red or white patch inside the mouth, a lump or thickening in the cheek, unexplained bleeding, persistent mouth pain, difficulty chewing or swallowing, and a feeling that something is caught in the throat. Loose teeth or a change in how dentures fit can also be a sign. None of these always mean cancer, but persistent symptoms deserve a professional examination.

What causes mouth cancer?

The main risk factors for mouth cancer are tobacco use in any form — smoking, gutkha, khaini or paan masala — and chewing betel quid (areca nut). Heavy alcohol use raises the risk further, and tobacco plus alcohol together raise it more than either alone. Other factors include certain HPV infections, prolonged sun exposure to the lips, and a diet low in fruits and vegetables. Avoiding tobacco and limiting alcohol are the most effective ways to lower your risk.

How is mouth cancer diagnosed?

Diagnosis usually begins with a physical examination of the mouth and neck. If an area looks suspicious, the doctor takes a small tissue sample, called a biopsy, which a pathologist examines under a microscope to confirm cancer. Imaging tests such as a CT scan, MRI or PET-CT may follow to find out the size of the tumour and whether it has spread. At CION, findings are discussed by a tumor board so a clear, evidence-based plan is made for each patient.

Is mouth cancer treatable?

Yes. Mouth cancer is treatable, and outcomes are best when it is found early. Treatment depends on the stage and location and may involve surgery, radiation therapy, chemotherapy, targeted therapy or a combination. Reconstruction and rehabilitation help restore speech, swallowing and appearance. CION reports a 1-year survival rate of 80.0% for oral cancer compared with the national average of 71.6% (*1-year survival; source ICMR/NCRP). A team of medical, surgical and radiation oncologists plans care together.

How can mouth cancer be prevented?

The most important step is to avoid all forms of tobacco, including cigarettes, gutkha, khaini and betel quid with areca nut. Limiting alcohol, eating plenty of fruits and vegetables, protecting your lips from strong sun, and keeping up regular dental check-ups all help. A dentist or doctor can spot suspicious patches early during a routine examination. If you use tobacco, quitting at any age lowers your risk, and support is available to help you stop.

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