Targeted Therapy — Is Not Just for the Rich
The belief that targeted therapy is only for wealthy patients is one of the most common — and most harmful — myths in cancer care. It stops families from asking the right questions before they conclude a treatment is out of reach.
Medically reviewed by Dr. C. Raghavendra Reddy, Medical Oncologist, MBBS (Gold Medal) · DNB · DM (Medical Oncology, Gold Medal) · Last reviewed August 2026
- Branded is not the only option — Generic targeted drugs are CDSCO-approved and available in India for several cancer types.
- Cost varies widely by drug — Some targeted therapies cost far less than many chemotherapy regimens. Others are genuinely expensive. The category is not one price.
- Support schemes exist — Government insurance, state cancer schemes, and manufacturer patient assistance programmes all reduce out-of-pocket costs for eligible patients.
- Ask before you conclude — The affordability question has a specific answer for your drug. That answer comes from your team, not from the sticker price of a branded medicine.
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Targeted therapy is expensive in its branded form, but generic versions of several targeted drugs are CDSCO-approved and available in India at much lower cost. Government schemes such as PMJAY cover cancer treatment for eligible families. Whether you can afford it depends on which drug is needed and what support you can access — not on a single wealth line.
Is targeted therapy really only for patients who can pay?
Targeted therapy is only for patients who can afford private care.
This is not always true. Generic versions of several targeted drugs are CDSCO-approved and available from multiple manufacturers in India. For some drugs — particularly older molecules now off-patent — generic versions have been on the market for years at a fraction of branded costs. Government hospital formularies increasingly include these generics.
Targeted therapy always costs more than chemotherapy.
Not consistently. Cost depends on the specific drug and whether a generic exists. Some targeted drugs that have been off-patent for years cost less than several chemotherapy regimens when prescribed in generic form. Newer biologics and recently approved agents are genuinely expensive. The comparison is drug to drug, not category to category.
If the branded drug is unaffordable, there is no way to get targeted therapy.
Incorrect. When a generic equivalent exists, your oncologist can prescribe it. Manufacturer patient assistance programmes provide the drug free or at reduced cost to eligible patients. PMJAY and state government cancer schemes cover some targeted therapies for eligible families. The right step is asking your treating team what is available for your specific drug before concluding it is impossible.
The high prices quoted online are what everyone pays.
The prices quoted in news reports and online typically reflect the branded drug at full retail cost. They are not wrong, but they are not the whole picture. What a patient actually pays depends on whether a generic is prescribed, whether a government scheme covers the drug, and whether a patient assistance programme applies to their situation.
What do these terms actually mean?
- Targeted therapy
- A group of drugs that block specific proteins or signals that help cancer cells grow. Unlike chemotherapy, which broadly affects fast-dividing cells, targeted drugs are designed to act on a known molecular driver of a specific cancer.
- Generic targeted drug
- A drug containing the same active molecule as the branded original, approved by CDSCO after demonstrating bioequivalence — meaning it releases the same amount of drug into the body in the same way. It may be sold under a different name at a lower price.
- Biosimilar
- The generic equivalent of a biologic targeted drug. Biologics are made from living cells and are harder to replicate exactly than small-molecule drugs, so the regulatory standard is demonstrated similarity rather than strict equivalence. CDSCO applies its own biosimilar approval pathway.
- PMJAY (Pradhan Mantri Jan Arogya Yojana)
- India's government health insurance scheme for economically vulnerable families, providing coverage for hospitalisation including cancer treatment. Eligibility is based on Socio-Economic Caste Census data. Coverage includes certain cancer procedures and medicines listed in the scheme's package rates.
- Patient assistance programme (PAP)
- A scheme run by a drug manufacturer that provides the drug free or at reduced cost to patients who cannot afford full price. Most manufacturers of expensive targeted drugs operate one. Your hospital's oncology social worker or the manufacturer's helpline can confirm whether you qualify.
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Why do people believe targeted therapy is unaffordable?
The belief persists because it was true — partly, and for a specific period. When targeted therapy first reached India, only branded drugs at full price were available, and for some cancers those prices were genuinely beyond most families. The news stories quoting monthly drug costs in the lakhs were not wrong at the time.
The picture changed as drugs came off patent. Once the original manufacturer's patent expires, other companies can apply to CDSCO to produce a generic. Several targeted therapy molecules — including some used widely in blood cancers and lung cancer — are now available from multiple manufacturers at considerably lower cost.
The myth also persists because 'targeted therapy' is treated as a single thing with a single price. It is not. The category includes drugs that cost a modest amount per month in generic form and drugs that cost several lakhs per month with no generic equivalent. Assuming the worst-case price applies to all of them stops patients from asking whether their specific drug has an alternative.
The most useful thing you can do is name the drug your oncologist has recommended and ask three questions: Does an approved generic exist for this molecule? Does PMJAY or a state scheme cover this drug for my cancer type? Does the manufacturer operate a patient assistance programme? Each answer is specific and findable — your treating team is the right starting point.
Did you know?
Several targeted cancer drugs used widely in India have been off-patent for years. Once a molecule goes off-patent, any CDSCO-licensed manufacturer can produce a generic version — which is why the same active drug that once had only one branded source can now be prescribed from multiple manufacturers at a much lower cost.
Asking your oncologist whether a generic exists for your specific drug is not an unusual question. It is the right one.
Source: CDSCO (Central Drugs Standard Control Organisation) generic drug approval framework
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Frequently asked questions
How much cheaper are generic targeted drugs compared to branded ones?
The difference varies by drug and no single figure would be reliable across treatments, manufacturers, or time. What is consistent is that a CDSCO-approved generic delivers the same active molecule in the same amount, so the clinical effect is expected to be equivalent at a lower price. Ask your oncologist to name the specific molecule being recommended, then ask the hospital pharmacy or a licensed supplier what the generic version costs. For some drugs the difference is substantial; for others no generic may yet exist.
Does PMJAY cover targeted therapy?
PMJAY covers hospitalisation costs for eligible families across a range of cancer procedures and certain medicines under scheme package rates. Whether your specific targeted drug is covered depends on the cancer type, the drug, and the package at the empanelled hospital where you are being treated. The scheme's coverage list is updated periodically. Ask the PMJAY desk at your treating hospital to check whether your drug and treatment plan fall under a covered package — they can verify this directly from the scheme records.
What is a patient assistance programme and how do I access it?
A patient assistance programme is a scheme run by the drug manufacturer to supply the drug free or at reduced cost to patients who cannot afford full price. Most manufacturers of expensive targeted drugs operate one, though eligibility criteria and the extent of support vary. The starting point is to ask your oncologist or the hospital's oncology social worker — they will know which programmes exist for your drug and what documents you need to apply. You can also contact the manufacturer's medical helpline directly.
Can I ask my oncologist to prescribe a generic instead of the branded drug?
Yes, and it is a reasonable question to raise. Your oncologist can tell you whether a CDSCO-approved generic exists for the molecule they are recommending and whether it is appropriate in your situation. There are cases where a specific formulation matters — for some drugs the release profile or the route of administration differs between versions — and your oncologist will flag that if it applies. In many cases a generic is a straightforward alternative, and the question is simply whether one is available for your drug.
If I cannot afford targeted therapy, does that mean I have no treatment options?
No. Treatment decisions are based on what the evidence supports for your cancer type and stage, not on what you can afford. If targeted therapy is the recommended treatment and cost is a barrier, the right conversation with your oncologist covers generics, government scheme coverage, and patient assistance programmes before concluding it is out of reach. If targeted therapy genuinely cannot be accessed, your team will discuss what the alternative evidence-based treatment is — and that alternative may be equally appropriate for your situation.