Medical Oncologist
Prostate cancer: treatment cost
Enzalutamide Price in India: — Brand, Generic and Monthly Cost
Indian-made generic enzalutamide is available at a fraction of the originator brand cost. Knowing the difference — and how to ask for it — can save your family several lakhs a year.
Medically reviewed by Dr. T. Raghavender Reddy, Medical Oncologist, MBBS · DM (Medical Oncology) · MD (Radiation Oncology) · Last reviewed August 2026
- Generics cost far less — CDSCO-approved Indian-made enzalutamide typically costs a fraction of the originator brand price each month.
- Multiple manufacturers — Several Indian pharmaceutical companies supply enzalutamide, giving you options across pharmacies and hospital dispensaries.
- Ask for it by INN — Prescribing by the generic name — enzalutamide — means any CDSCO-approved product can fill the prescription.
- Schemes can reduce cost further — Ayushman Bharat PMJAY and Pradhan Mantri Jan Aushadhi Kendras may bring the out-of-pocket cost down significantly.
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Indian-made generic enzalutamide is available at a fraction of the originator brand cost. As of 2025, indicative monthly prices range from roughly ₹8,000–₹30,000 for Indian generics to ₹80,000–₹1,50,000 for the originator brand, before scheme support. Several CDSCO-approved generic manufacturers supply the Indian market, and your oncologist can prescribe by the generic name to give you access to all of them.
What does enzalutamide cost per month in India?
| Option | Dose form | Indicative monthly cost (2025 data) | Notes |
|---|---|---|---|
| Originator brand (Xtandi) | 40 mg capsules | ₹80,000 – ₹1,50,000 | Retail and private hospital pharmacy; before any manufacturer assistance program |
| Indian-manufactured generic | 40 mg tablets or capsules | ₹8,000 – ₹30,000 | Multiple CDSCO-approved suppliers; price varies by pharmacy and city |
| Pradhan Mantri Jan Aushadhi Kendra | 40 mg | Lower than retail; confirm at your nearest centre | Availability varies by state and current stock |
| Hospital institutional rate | 40 mg | Varies — ask the dispensary directly | Many oncology centres negotiate lower rates than retail pharmacies |
Why is Indian generic enzalutamide so much cheaper?
Enzalutamide was developed by Astellas and sold globally as Xtandi at a price that put it out of reach for most families in India. India's Patents Act and the framework for compulsory licensing created conditions for lower-cost local manufacturing.
Several Indian pharmaceutical companies — including Cipla and Natco — entered the market with CDSCO-approved generic versions. Because multiple manufacturers compete, prices have come down significantly and continue to do so.
A generic version contains the same active molecule at the same dose. CDSCO approval requires bioequivalence data demonstrating the generic behaves the same way in the body as the originator product.
How can you bring the monthly cost down further?
If your family holds an Ayushman Bharat card, ask your treating centre whether enzalutamide is listed under PMJAY for your diagnosis. Coverage and the medicines list vary by state and are revised periodically — do not assume it is or is not covered without checking.
Pradhan Mantri Jan Aushadhi Kendras stock a range of generic oncology medicines at regulated prices. Call ahead to confirm enzalutamide is in stock at your nearest centre before making the trip.
Ask the hospital dispensary about institutional pricing. Oncology centres often negotiate supply contracts at rates below what you would pay at a retail pharmacy, and some pass part of that saving on.
Contact the manufacturer's patient access team. Some Indian companies run hardship programs or can direct you to a state government supply scheme your oncology team may not have mentioned.
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Originator brand versus Indian generic: what is the same and what differs?
| Originator brand (Xtandi) | Indian-manufactured generic | |
|---|---|---|
| Active molecule | Enzalutamide 40 mg | Enzalutamide 40 mg |
| Regulatory approval | CDSCO-approved for India | CDSCO-approved (each manufacturer separately) |
| Bioequivalence data | Reference product | Required for CDSCO approval before market entry |
| Indicative monthly cost (2025) | ₹80,000 – ₹1,50,000 | ₹8,000 – ₹30,000 |
| Manufacturer assistance | Available — contact Astellas India | Varies by manufacturer; ask at the dispensary |
| Where to obtain | Retail pharmacy, private hospital | Most oncology pharmacies; Jan Aushadhi Kendras (stock permitting) |
How to access lower-cost enzalutamide
Ask for an INN prescription
Request that your oncologist write the prescription using the generic name — enzalutamide — rather than a brand name. This gives any CDSCO-approved manufacturer's product the right to fill it, so you are not locked to one supplier or pharmacy.
Check your hospital dispensary first
Many oncology centres stock one or more generic versions at institutional rates. This is often the fastest and lowest-cost source, and the dispensary team can tell you what is currently available and at what price.
Call your nearest Jan Aushadhi Kendra
Pradhan Mantri Jan Aushadhi Kendras stock regulated-price generics. Confirm by phone that enzalutamide is in stock before visiting — supply is not uniform across all centres and varies by state.
Check PMJAY eligibility
If your family holds an Ayushman Bharat card, ask the hospital's PMJAY desk or the scheme helpline whether enzalutamide is listed for your diagnosis under your state's package. A hospital social worker can help navigate this.
Contact the manufacturer directly
Both the originator company and Indian generic manufacturers run patient access or hardship programs. Your oncology team's coordinator can help connect you, or you can reach the company's medical information line directly.
Did you know?
The entry of CDSCO-approved Indian generic manufacturers into the enzalutamide market brought the monthly cost down to a fraction of what it was at originator pricing alone — making continued treatment financially possible for many more families.
If cost is making you consider stopping or skipping doses, tell your oncologist or the hospital social worker before you miss anything. There are options your team can explore only if they know.
Source: CDSCO (Central Drugs Standard Control Organisation), India
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Common questions
Frequently asked questions
Is generic enzalutamide as effective as Xtandi?
Yes — for a generic to receive CDSCO approval it must demonstrate bioequivalence to the originator, meaning it delivers the same active molecule to your bloodstream at the same rate. The active ingredient is identical: enzalutamide 40 mg. If you are already on a generic version and your oncologist is monitoring your response, the clinical expectation is the same as for the originator. Always tell your treating team if you change from one manufacturer's product to another so they can note it in your record.
Which Indian companies make generic enzalutamide?
Several Indian pharmaceutical manufacturers have received CDSCO approval for enzalutamide, including Cipla and Natco among others. The list of approved manufacturers grows over time. Your oncology dispensary will stock one or more of these products. If you want to compare your options, ask the dispensary which products they carry and at what price — they have the most current information and can tell you what is in stock.
Can I switch from the originator brand to a generic?
In most cases, yes — but always do it with your oncologist's knowledge rather than on your own. Tell your treating team you want to switch and why, so they can note the change and continue monitoring your response. Do not stop treatment or miss doses while arranging the switch. If there is any delay in sourcing the generic, your team needs to know so they can advise you on what to do in the interim.
Does Ayushman Bharat PMJAY cover enzalutamide?
PMJAY may cover enzalutamide for your diagnosis, but the covered medicines and conditions vary by state and are updated periodically — so whether it applies to you depends on your state's package and your specific diagnosis and stage. The most reliable way to check is through your hospital's PMJAY desk or the scheme's toll-free helpline. A hospital social worker can also help you check and apply. Do not assume it is either covered or excluded without verifying against the current list.
Does my oncologist need to prescribe by brand name?
No. If your oncologist prescribes using the INN — enzalutamide — any CDSCO-approved manufacturer's product can legally fill the prescription. Some doctors write a brand name out of habit, or because a particular product is stocked at that centre. You can ask for the INN to be written instead. There is no clinical reason to be restricted to one manufacturer's version when other approved options are available and cheaper.
What if we cannot afford it even with a generic?
Tell your oncologist or the hospital social worker before you miss a dose. Many oncology centres have access to compassionate supply channels, state government schemes, or manufacturer hardship programs that are not routinely mentioned unless someone asks. Missing doses because of cost is something your treating team needs to know about — it affects how they manage your treatment, and there may be a path you have not yet been shown. You are not expected to find it alone.