Sex and relationships
Erectile difficulties during chemotherapy
Difficulty getting or keeping an erection during chemotherapy is common and usually temporary. Tiredness, nausea, anxiety, low testosterone, medicines and nerve effects can all contribute. Many men never mention it, and nobody asks. It is a medical symptom like any other, and help ranges from treating the causes to medicines and other options your team can discuss.
The short answer
Why can chemotherapy cause erection problems?
Difficulty getting or keeping an erection is common during chemotherapy, and for most men it is temporary. An erection depends on energy, desire, healthy blood flow, working nerves and normal hormone levels, and treatment can affect all of them at once. Deep tiredness, nausea and pain reduce interest and stamina. Some chemotherapy can lower testosterone for a while. Medicines for sickness, pain, sleep, mood and blood pressure can interfere with erections. Nerve effects from medicines such as cisplatin, oxaliplatin and vincristine can reduce sensation. And anxiety about cancer, performance or hurting a partner can make it worse.
Many men never mention it, and many doctors never ask, so the problem is left untreated. It is a medical symptom like any other, and help exists. Treating tiredness, pain and low mood, reviewing medicines, and checking hormone levels can help. Tablets such as sildenafil and tadalafil work for many men, but they are not safe with some heart medicines, so they must be discussed with your doctor first. Vacuum devices, injections and counselling are other options. Surgery or radiotherapy to the prostate, bladder or rectum can cause longer lasting problems, and specialist help is especially useful then.
Usually temporary with chemotherapy alone
For most men, erections improve as energy returns and hormones recover after treatment.
Heart and diabetes matter
Erection problems can also be a sign of blood vessel disease, diabetes or high blood pressure, which are worth checking.
Condoms still apply
Protect your partner for the first days after each treatment, and use contraception if pregnancy is possible.
You can raise this privately with your oncologist. It is a common, treatable side effect, and asking will not affect your cancer care.Why it happens
Causes of erection difficulties during treatment
- Tiredness and illness
- Fatigue, nausea, pain and diarrhoea leave little energy for sex and reduce arousal.
- Lower testosterone
- Some chemotherapy, steroids and hormone treatments for prostate cancer lower testosterone, reducing desire and erections.
- Medicines
- Some anti-sickness, pain, sleep, antidepressant and blood pressure medicines can affect erections.
- Nerve effects
- Numbness and tingling from some medicines can reduce sensation and response.
- Anxiety and mood
- Worry about cancer, body image, performance or infecting a partner can make erections harder.
- Surgery and radiotherapy
- Pelvic surgery or radiotherapy can damage nerves and blood vessels, sometimes causing longer-term difficulties.
Not sure whether this applies to you?
Ask an oncologistWhat help exists
Options your team may discuss
Start by talking to your doctor, not by buying products online.
Treat the underlying causes
Improving sleep, pain control, nausea and mood, and reviewing medicines, can restore erections for some men.
Ask about
- Changing a medicine
- Checking testosterone
Erection tablets
Sildenafil and tadalafil help many men but are not safe with nitrate heart medicines and some other conditions. Your doctor must check first.
Vacuum devices
A device that draws blood into the penis can work without medicines, and may be useful after pelvic surgery.
Other options
- Injections or gels prescribed by a urologist
- Implants, rarely, for long-term problems
Counselling
A counsellor or psycho-oncologist can help with anxiety, confidence and communication with a partner.
Staying active
Gentle regular activity supports blood flow, energy and mood.
An erection lasting several hours that will not go down, especially after tablets or injections · chest pain, breathlessness or fainting during or after sex · bleeding from the penis that does not stop · fever with pain or swelling in the genitals · sudden severe pain in the testicles · blood in the urine with low platelets. Go to the nearest emergency department and say clearly that the person is on chemotherapy.
Being straight with you
What this page cannot tell you
It cannot tell you which treatment is safe for you, or whether your difficulties will fully recover. That depends on your cancer, your treatments, your heart health and other conditions. Your oncologist, and if needed a urologist, can advise.
It also cannot tell you whether testosterone treatment is appropriate. It is not safe after some cancers, including prostate cancer, and must only be considered with specialist advice.
Avoid products bought online
Unregulated tablets and herbal products for erections may contain hidden medicines that interact dangerously with treatment.
Heart medicines and tablets
Never combine erection tablets with nitrate medicines for chest pain. Tell every doctor what you take.
Low platelets and injections
Penile injections are not suitable when platelets are very low because of bleeding risk.
Fertility is a separate question
Erections and fertility are different. Chemotherapy can affect sperm even when erections are normal. Ask about sperm banking before treatment if possible.
Morning erections are a clue
If you still have erections on waking, the physical ability may be intact and anxiety or tiredness may be the main factor.
Partners benefit from knowing
Explaining the cause helps partners avoid feeling rejected.
Diabetes and blood pressure checks
New erection problems can signal these conditions. Ask for a check.
Recovery can take months
Improvement often follows the return of energy and hormones after treatment.
Asking is common
Urologists and oncologists see this often. There is no need to feel embarrassed.
Take pressure off performance
Worrying about whether an erection will happen can make it less likely. Agreeing with your partner that closeness does not have to lead to intercourse often reduces anxiety and allows natural responses to return over time.
Alcohol and smoking make it worse
Both reduce blood flow and nerve function. Cutting down alcohol and stopping smoking can improve erections as well as overall recovery.
Talking to your partner about it
Many men withdraw from closeness altogether rather than risk an erection failing, and partners may read that as rejection. Explaining simply that treatment is affecting your body, and that you still want to be close, usually eases tension on both sides. Couples who keep touching, cuddling and talking tend to find their way back to sex more easily once the body recovers.
Tiredness and timing
Erections are often easier when you are rested. Choosing a time of day when energy is better, such as the morning, and avoiding the days straight after treatment can make a noticeable difference while you recover.
Diabetes, blood pressure and cholesterol
These conditions narrow blood vessels over time and make erection problems more likely. Keeping them well controlled during and after treatment helps erections as well as heart health, so continue those medicines and keep up with checks.
What a urologist can offer
A urologist can assess blood flow and nerves, explain all the options clearly, and arrange treatments that your oncologist may not prescribe, such as injections or devices. Referral is reasonable if difficulties last beyond the end of treatment.
What to do next
Tell your oncologist privately, ask whether medicines or hormones may be involved, have heart, diabetes and blood pressure checked, avoid online products, ask before using erection tablets, and consider counselling or a urologist referral if difficulties continue.
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Commonly believed
Four beliefs about erections and chemotherapy
They are a common side effect of treatment, not a measure of masculinity, and they often improve.
Some are dangerous with heart medicines. Always check with your doctor.
With chemotherapy alone, most men find erections improve after treatment.
Oncologists and urologists regularly help men with erection problems.
Questions we are asked
Common questions about erectile difficulties
Why does chemotherapy cause erectile problems?
Tiredness, lower testosterone, medicines, nerve effects and anxiety can all affect erections during treatment.
Is it permanent?
Usually not with chemotherapy alone. It can last longer after pelvic surgery or radiotherapy, where specialist help is useful.
What help exists?
Treating causes, reviewing medicines, erection tablets if safe, vacuum devices, injections, and counselling.
Can I take sildenafil during chemotherapy?
Only after checking with your doctor, because it can interact with heart medicines and other conditions.
Should my testosterone be checked?
It may be useful. Ask your team. Testosterone treatment is not safe after some cancers.
Does it affect fertility?
Erections and fertility are separate. Chemotherapy can affect sperm even if erections are normal.
Do I still need condoms?
Yes, for the first days after each treatment and to prevent pregnancy.
Who should I see?
Start with your oncologist, who can refer you to a urologist or counsellor.
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Sources
- American Cancer Society — Sex and the Man With Cancer
- National Cancer Institute — Sexual Health Issues in Men With Cancer
- Macmillan Cancer Support — Sex and relationships
This page is general information, not a prescription. Do not change or stop any treatment based on what you read here. If anything is worrying you, contact your own treating team — or call our helpline and we will help you reach the right specialist.
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