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Fever during chemotherapy

Your Child Has a Fever — on Chemotherapy

A fever during chemotherapy can mean your child's body cannot fight infection on its own. Do not wait until morning. This is one situation where going now is always the right choice.

Medically reviewed by Dr. C. Raghavendra Reddy, Medical Oncologist, MBBS (Gold Medal) · DNB · DM (Medical Oncology, Gold Medal) · Last reviewed September 2026

  • Not an ordinary fever — A suppressed immune system cannot fight infection the way a healthy child's can.
  • Act now, not in the morning — Waiting to see if the fever settles is not safe during chemotherapy.
  • Know your threshold number — Your team will have given you a temperature to watch for at discharge. Find that card now.
  • Know which hospital to go to — Go to the hospital your oncology team named, not simply the nearest emergency department.
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A fever during chemotherapy is a medical emergency in children. Your child's blood counts may be too low to fight infection without hospital treatment. Do not give paracetamol and wait to see if it settles. Call your oncology team's emergency number now, or go straight to the emergency department they have told you to use.

If a symptom below applies to you, do not wait for a callback. Call 1800-202-8726 or go to your nearest emergency department.

If you are worried right now, call

Our helpline is answered by clinical staff. If a symptom is on the list above, do not wait for a callback — call, or go to your nearest emergency department.

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Dr. Naresh Gundu
Medical Oncologist

Dr. Naresh Gundu

MBBS, DNB (Internal Medicine), DM (Medical Oncology)

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Dr. C. Raghavendra Reddy
Medical Oncologist

Dr. C. Raghavendra Reddy

MBBS(Gold Medal), DNB(General Medicine), DM(Medical Oncology)(Gold Medal)

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Dr. Bharati Devi Gorantla
Medical Oncologist

Dr. Bharati Devi Gorantla

MBBS, MD(General Medicine), DM(Medical Oncology)(Adyar,Chennai), ECMO, MRCP SCE(UK)

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Dr. Owais Mohammed
Medical Oncologist

Dr. Owais Mohammed

MBBS, MD (General Medicine), DrNB (Medical Oncology), ECMO, MRCP SCE (Medical Oncology) (UK)

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Dr. T. Raghavender Reddy
Medical Oncologist

Dr. T. Raghavender Reddy

MBBS, DM (Medical Oncology), MD (Radiation Oncology)

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Medical Oncologist

Dr. N. Kiranmayee

MBBS, DM (Medical Oncology), MD (Internal Medicine)

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Dr. Muralidhar Muddusetty
Surgical Oncologist

Dr. Muralidhar Muddusetty

MBBS (AIIMS), MS (Surgery) (AIIMS), DNB (Surgical Oncology), MRCS (Edinburgh)

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Dr. Raghavendra Naik
Surgical Oncologist

Dr. Raghavendra Naik

MBBS, MS (General Surgery), M.Ch (Surgical Oncology)

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Dr. Mohammed  Imaduddin
Surgical Oncologist

Dr. Mohammed Imaduddin

M.B.B.S, MS (General Surgery), M.Ch (Surgical Oncology)

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Dr. Vinay Mamidala
Surgical Oncologist

Dr. Vinay Mamidala

MBBS, MS(General Surgery), M.Ch(Surgical Oncology), FMAS, FARIS(Ongoing)

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Dr. Paila Gowri Naidu
Surgical Oncologist

Dr. Paila Gowri Naidu

MBBS, MS (General Surgery), M.Ch (Surgical Oncology), FMAS

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Dr. Venkata Sushma P
Radiation Oncologist

Dr. Venkata Sushma P

MBBS, MD (Radiation Oncology)

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Dr. Kirti Ranjan Mohanty
Radiation Oncologist

Dr. Kirti Ranjan Mohanty

MBBS, MD (Radiation Oncology)

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Dr. Gangadhar Vajrala
Radiation Oncologist

Dr. Gangadhar Vajrala

MBBS, MD (Radiation Oncology), MPH

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Dr. Basudev Pokhrel
Hematologist

Dr. Basudev Pokhrel

MBBS, M.D (Immunohematology & Blood Transfusion)

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Interventional Radiologist

Dr. Mohammed Imran

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Surgical Oncologist

Dr. Vajja Sandeep Kumar

MBBS, MS (General Surgery), DrNB (Surgical Oncology), FALS Oncology

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Dr. Sridhar Kamani

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Not sure whether this counts as an emergency?

Call the helpline. It is always better to check than to wait.

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How do you tell whether this fever needs emergency care right now?

What you are seeingLower concern — call your teamEmergency — go now
Child's temperatureMild rise, child alert and drinking normallyAt or above the number your team gave you at discharge — or any fever where you do not have that number
Child's appearanceAwake, talking, taking fluidsLimp, very drowsy, hard to rouse, or unusually quiet
BreathingNormal rate and effortFaster than usual, laboured, or noisy
Central line or port siteNo change at the insertion siteRedness, swelling, discharge, or pain at the site
Typically startsCan happen at any point during treatmentMost often in the days after chemotherapy when blood counts are at their lowest, but can occur at any time

What should you bring to the emergency department?

Bring your child's oncology card or the most recent discharge summary. This tells the emergency team who is treating your child, which chemotherapy they are on, and when the last dose was given.

If your child has a central line or port, bring the care card for it. Emergency staff need to know the line type before they can access it.

Note the time the fever started and the highest temperature reading you have taken. The emergency team will ask.

Do not wait to pack a full bag. These three things and your child are enough to leave right now.

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Common questions

Frequently asked questions

Can I give paracetamol to bring the fever down before going to hospital?

Ask your oncology team before giving any medicine — they may have given you specific instructions at discharge. The concern is that paracetamol can reduce the fever and make your child appear better than they are, which can delay the treatment they actually need. If you are already on your way to the emergency department, tell the team on arrival what you gave and when. Giving paracetamol is never a reason to delay leaving.

Do we really need to go tonight, or can we wait until the clinic opens in the morning?

Do not wait until morning. A child on chemotherapy may have very few white blood cells — the cells that fight infection — and without them a bacterial infection can become serious within hours, not days. Your oncology team's emergency number exists specifically for this situation. Call it now, whatever the time. If you cannot reach anyone, go directly to the emergency department your team named.

What will happen when we arrive at the emergency department?

Tell the reception desk immediately that your child is on chemotherapy. This usually means they are seen quickly. The team will check temperature, pulse, and blood pressure, and take blood to measure white cell counts and look for the source of infection. If counts are very low or there are signs of serious infection, your child will most likely be admitted for close monitoring and treatment while results come back.

Why is fever during chemotherapy more dangerous than a normal childhood fever?

A healthy child with a fever has an immune system working hard to fight the infection. A child on chemotherapy may have very few white blood cells — the cells that do that fighting. Without them, a bacterial infection that a healthy child's body would handle can spread very quickly. This is why a fever that would be manageable at home for another child is treated as a potential emergency during chemotherapy, and acted on the same night.

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