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Emergencies & Red Flags

When to Call the Helpline — vs Go Straight to Hospital

Some symptoms during chemotherapy need you at the emergency department within minutes. Others need a helpline call before the day is out. This page tells you which is which — and makes the case for going in when you are not sure.

Medically reviewed by Dr. Naresh Gundu, Medical Oncologist, MBBS (Chalmeda Anand Rao Institute of Medical Sciences, Karimnagar) · DNB Internal Medicine (Sir Gangaram Hospital, New Delhi) · DM Medical Oncology (AIIMS) · Last reviewed September 2026

  • Fever means go, not call — Any fever during chemotherapy is a potential emergency. Do not wait for a helpline callback before leaving the house.
  • New symptoms need same-day contact — Side effects that are new, worsening, or worrying you belong on the helpline today, not at your next scheduled visit.
  • When in doubt, go in — The risk of going in and being told you are fine is a short wait. The risk of waiting at home with a serious reaction is not.
  • Red flags are for emergency care — For red flag symptoms, do not manage at home with fluids or rest. Go to the emergency department.
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During chemotherapy, fever, difficulty breathing, or uncontrolled bleeding need the emergency department immediately — do not wait to call. For symptoms that worry you but are not immediately dangerous, call your oncology helpline the same day. NCCN and ASCO guidance is clear: when in doubt, go in.

If a symptom below applies to you, do not wait for a callback. Call 1800-202-8726 or go to your nearest emergency department.

When should you call the helpline instead of going straight in?

Call the helpline when you have a new symptom that worries you but is not immediately life-threatening — for example, mild nausea that started today, a rash you have not seen before, or tingling in your hands or feet.

Call if a known side effect is getting worse rather than better, or if you are unsure whether what you are feeling is expected.

The helpline team will tell you whether to come in, wait, or monitor. If your gut says something is wrong, going in without calling first is always appropriate.

If you are worried right now, call

Our helpline is answered by clinical staff. If a symptom is on the list above, do not wait for a callback — call, or go to your nearest emergency department.

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Dr. Naresh Gundu
Medical Oncologist

Dr. Naresh Gundu

MBBS, DNB (Internal Medicine), DM (Medical Oncology)

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Dr. C. Raghavendra Reddy
Medical Oncologist

Dr. C. Raghavendra Reddy

MBBS(Gold Medal), DNB(General Medicine), DM(Medical Oncology)(Gold Medal)

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Dr. Bharati Devi Gorantla
Medical Oncologist

Dr. Bharati Devi Gorantla

MBBS, MD(General Medicine), DM(Medical Oncology)(Adyar,Chennai), ECMO, MRCP SCE(UK)

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Dr. Owais Mohammed
Medical Oncologist

Dr. Owais Mohammed

MBBS, MD (General Medicine), DrNB (Medical Oncology), ECMO, MRCP SCE (Medical Oncology) (UK)

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Dr. T. Raghavender Reddy
Medical Oncologist

Dr. T. Raghavender Reddy

MBBS, DM (Medical Oncology), MD (Radiation Oncology)

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Dr. N. Kiranmayee
Medical Oncologist

Dr. N. Kiranmayee

MBBS, DM (Medical Oncology), MD (Internal Medicine)

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Dr. Muralidhar Muddusetty
Surgical Oncologist

Dr. Muralidhar Muddusetty

MBBS (AIIMS), MS (Surgery) (AIIMS), DNB (Surgical Oncology), MRCS (Edinburgh)

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Dr. Raghavendra Naik
Surgical Oncologist

Dr. Raghavendra Naik

MBBS, MS (General Surgery), M.Ch (Surgical Oncology)

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Dr. Mohammed  Imaduddin
Surgical Oncologist

Dr. Mohammed Imaduddin

M.B.B.S, MS (General Surgery), M.Ch (Surgical Oncology)

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Dr. Vinay Mamidala
Surgical Oncologist

Dr. Vinay Mamidala

MBBS, MS(General Surgery), M.Ch(Surgical Oncology), FMAS, FARIS(Ongoing)

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Dr. Paila Gowri Naidu
Surgical Oncologist

Dr. Paila Gowri Naidu

MBBS, MS (General Surgery), M.Ch (Surgical Oncology), FMAS

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Dr. Venkata Sushma P
Radiation Oncologist

Dr. Venkata Sushma P

MBBS, MD (Radiation Oncology)

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Dr. Kirti Ranjan Mohanty
Radiation Oncologist

Dr. Kirti Ranjan Mohanty

MBBS, MD (Radiation Oncology)

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Dr. Gangadhar Vajrala
Radiation Oncologist

Dr. Gangadhar Vajrala

MBBS, MD (Radiation Oncology), MPH

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Dr. Basudev Pokhrel
Hematologist

Dr. Basudev Pokhrel

MBBS, M.D (Immunohematology & Blood Transfusion)

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Dr. Mohammed Imran
Interventional Radiologist

Dr. Mohammed Imran

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Dr. Vajja Sandeep Kumar
Surgical Oncologist

Dr. Vajja Sandeep Kumar

MBBS, MS (General Surgery), DrNB (Surgical Oncology), FALS Oncology

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Dr. Sridhar Kamani
Surgical Oncologist

Dr. Sridhar Kamani

MBBS, MS (General Surgery), DrNB (Surgical Oncology)

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Not sure whether this counts as an emergency?

Call the helpline. It is always better to check than to wait.

Book Free Consultation Call 1800 202 8726

Call the helpline today if any of these apply

  • A new side effect you have not had before, even if it seems mild
  • A known side effect that has clearly worsened over the past day
  • Nausea or vomiting that stops you eating but you can still keep some fluid down
  • Pain that is new, or worse than your usual level
  • Mouth sores that make it hard to eat or drink
  • Tiredness that has not improved with rest
  • Anything worrying you, even if you are not sure it is a side effect

How do you decide?

SituationCall helpline todayGo straight in now
FeverAny fever, at any level
VomitingNausea you can still keep some fluid throughCannot keep any fluid down for several hours
BleedingMinor bleeding that slows and stopsBleeding that does not stop, or spreading bruising
BreathlessnessMild, new, comfortable at restSevere, sudden, or with chest pain
Confusion or collapseAny sudden confusion, difficulty waking, or collapse
RashNew rash or mild itching you have not seen beforeBlistering, peeling, or spreading rapidly with pain
Typically startsSide effects needing the helpline are most common in the days after each cycle, but can appear at any timeEmergencies can happen at any point — including between cycles and after treatment ends

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Common questions

Frequently asked questions

What if the helpline is busy or I cannot get through?

Go to the nearest emergency department and tell them you are on chemotherapy. You do not need to wait for a callback if you cannot reach one. Tell the triage nurse you are on active treatment — this ensures you are seen promptly. Do not stay at home trying to reach someone when symptoms are worsening.

Is it ever safe to wait until the next day?

For very mild, stable side effects that are not getting worse and that your team already told you to expect, waiting until morning to call is usually reasonable. Any symptom that is worsening, any fever, any bleeding, any breathing difficulty, or anything that feels wrong should not wait overnight. If you are asking yourself whether it can wait, that question is itself a reason to call today.

My family thinks I am overreacting. Should I still go?

Yes. Chemotherapy changes how your body responds to infection and injury, which means symptoms that seem minor can escalate quickly in someone on active treatment. The risk of going in and being told you are fine is a short wait. Your team will never judge you for coming in. Go, and let them decide.

What should I tell the emergency department when I arrive?

Tell them immediately that you are on chemotherapy, name the drugs if you know them, and say when your last cycle was. This changes how quickly you are seen and what tests are ordered. Carry your treatment summary card or a photograph of your drug regimen if you have one. If you have a fever, say so at the door.

Full index

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Blood Counts, Infection, Fever & Emergencies73

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