Emotional support
Feeling low during chemotherapy
Yes. Feeling flat, tearful, irritable or hopeless at points during treatment is extremely common and does not mean anything is wrong with you. What matters is the difference between low days that come and go with the cycle and a low mood that has settled in and stopped lifting at all.
The short answer
Is it normal to feel low during chemotherapy?
Yes. Feeling flat, tearful, irritable or hopeless at points during a course of treatment is extremely common, and it does not mean anything is wrong with you. What matters is the difference between low days that come and go with the cycle, and a low mood that has settled in and stopped lifting at all.
The second one needs help, and help exists. Nobody is expected to get through six months of treatment on willpower, and asking for support is not an admission that you are failing at being a patient.
Some of it follows the cycle
Steroids given with treatment lift the mood and then drop it a few days later, and many patients have a reliably difficult day or two. If your low days fall in the same place each cycle, say so, because that is useful information.
Some of it is physical and treatable
Poor sleep, pain, a low haemoglobin, an underactive thyroid and constant nausea all flatten the mood. Treating those often lifts it more than anything else does.
Some of it needs proper support
If it has lasted more than a couple of weeks, if you cannot sleep, if nothing interests you, or if you feel there is no point continuing, that is the point to tell your team.
If you have thoughts of harming yourself, tell somebody today. Do not wait for the next appointment.What to notice
The difference between a low patch and something needing help
- How long it has lasted
- A few difficult days each cycle is one thing. Two weeks or more of continuous low mood, with no better days at all, is a different thing and worth reporting.
- Whether anything still gives you any pleasure
- Low days where you still enjoy a grandchild's visit or a favourite programme are different from a flatness where nothing reaches you at all. That second state is the one to mention.
- Whether you are sleeping
- Lying awake most of the night, or waking very early and not getting back to sleep, tends to go with a mood that needs attention, and it also makes everything else worse.
- Whether you are eating
- Treatment reduces appetite anyway. Not eating because nothing seems worth the effort is a different problem and should be separated out from nausea and a sore mouth.
- Whether you have withdrawn from everybody
- Not wanting visitors on a hard day is sensible. Not wanting to speak to anybody at all, for weeks, and avoiding the people closest to you, is worth telling somebody about.
- Whether you have thoughts of harming yourself
- If so, tell somebody today, whether that is your oncologist, a nurse, or a relative who can ring them. This is urgent and there is help, and being on treatment makes it no less urgent.
Not sure whether this applies to you?
Ask an oncologistPractical
What helps, and what to ask for
Start with the physical causes; they are the ones most often missed.
Get the physical things checked first
Pain, sleep, nausea, a low haemoglobin, thyroid function and constipation all flatten the mood, and all are treatable. Ask for them to be looked at before assuming this is only psychological.
Mention specifically
- How you are sleeping
- Whether pain or nausea is constant
Ask about the steroid pattern
If your low days fall in the same place in every cycle, the steroids given with treatment may be part of it. Tell your team the pattern, because the schedule can sometimes be adjusted.
Ask for counselling by name
Psycho-oncology support or a counsellor, available at many centres and consistently under-used. Asking is an ordinary request and does not require you to be in crisis.
Say plainly
- I have been low for several weeks
- I would like to speak to somebody
Keep two anchors in the day
Out of bed and dressed, and out of the house or at least into daylight for a few minutes. On the flattest days these two do more than anything else available to you.
Tell one person the truth
Not the whole family; one person who will listen without trying to fix it or telling you to be positive. Patients consistently describe that as the thing that made the most difference.
You have thoughts of harming yourself or of not wanting to be here · you feel there is no point continuing treatment · you have not slept for several nights · you have stopped eating or drinking · you cannot look after yourself · you feel hopeless most of the day, most days · you are hearing or believing things others do not · you have stopped taking your medicines. Ring your hospital number or go to the nearest emergency department. Tell a relative so somebody else knows. This is urgent and help is available.
Being straight with you
What this page cannot tell you
It cannot tell you whether what you are feeling is an expected response to a hard six months or something that needs treatment in its own right, and it will not try to. That distinction needs somebody who can talk to you properly, and it is worth the appointment.
It also cannot give you a test or a threshold. There is no number here. The honest guide is duration, whether anything still reaches you, and whether you can still look after yourself.
Being low is not a failure of attitude
Patients are told constantly to stay positive, and it is one of the least helpful things said to anybody on treatment. Mood is not a moral achievement, and nobody's outcome depends on cheerfulness.
Do not stop or change any medicine on your own
If something is making you feel worse, tell your team so it can be reviewed properly. Stopping treatment or supportive medicines without telling anybody is how a difficult patch becomes a serious problem.
The attendant needs this page too
The relative who has been holding everything together for four months is frequently in worse shape than the patient and has never been asked. Both of you can ask for support.
What to do next
Tell your team how long you have felt this way and how you are sleeping. Ask for pain, nausea, haemoglobin and thyroid to be checked, ask about the steroid pattern, and ask for counselling by name. Tell one person the truth, and if you have thoughts of harming yourself, tell somebody today.
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Commonly believed
Four things said to patients who are low
Mood is not a moral achievement and nobody's outcome depends on cheerfulness. Being told to be positive mainly teaches patients to hide how they feel, which makes getting help harder.
A great deal can be done. Pain, sleep, nausea, a low haemoglobin and thyroid problems all flatten the mood and are treatable, and counselling is available at many centres and rarely requested.
It means you are on a long and demanding treatment. Nobody is expected to manage six months of this on willpower, and asking early is easier than asking in crisis.
Mood affects sleep, appetite, weight and whether people keep taking their medicines, all of which are your oncologist's concern. It is a clinical matter rather than an imposition.
Questions we are asked
Common questions about low mood on treatment
Is feeling low a side effect of chemotherapy?
Partly. Steroids given with treatment lift and then drop the mood, and tiredness, pain, poor sleep and a low haemoglobin all flatten it. The illness and the upheaval account for much of the rest.
How do I know if it is more than a low patch?
Look at duration, whether anything still gives you any pleasure, and whether you can still sleep, eat and look after yourself. Two weeks or more with no better days at all is worth reporting.
Who should I tell?
Your oncologist or the nurse at your next contact, and one person at home. Say how long it has lasted and how you are sleeping. Both are more useful than trying to describe the feeling itself.
Will they stop my treatment if I say I am struggling?
That is not how it works, and the fear of it keeps many patients silent. They are far more likely to treat the cause, adjust supportive medicines or arrange counselling.
Is counselling available at the hospital?
At many centres, yes. Ask whether psycho-oncology support or a counsellor is available, and ask the medical social worker if nobody else knows. It is under-used rather than unavailable.
Can medicines help with this?
Sometimes, and that is a decision for your doctors, who will also check what interacts with your treatment. Never start anything, including herbal or ayurvedic preparations, without telling them.
My relative is low but will not talk. What can I do?
Tell the team yourself at the next appointment, and sit with them without trying to fix it or telling them to be positive. If there is any mention of self-harm, treat it as urgent today.
Does it get better after treatment ends?
For many patients, gradually, though the first months afterwards can be unexpectedly hard. If it has not lifted a few months after finishing, raise it at follow-up rather than waiting longer.
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Patient stories
Hear it from people we have treated
Every story is a video, in the patient's own words. Nothing here is a written testimonial.
Sources
- Macmillan Cancer Support — Your feelings and cancer
- National Cancer Institute — Feelings and Cancer
- American Cancer Society — Emotional, Mental Health, and Mood Changes
This page is general information, not a prescription. Do not change or stop any treatment based on what you read here. If anything is worrying you, contact your own treating team — or call our helpline and we will help you reach the right specialist.
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