Metastatic breast cancer
Bone metastases in breast cancer: pain, fractures and treatment
Bone is the most common place breast cancer spreads to. Bone metastases can cause pain, fractures and high calcium, but treatment with whole-body therapy, bone-protecting medicines, radiation and sometimes surgery controls them for many women. This page explains what to expect.
On this page
- What are bone metastases, and how are they treated?
- How bone metastases are usually treated
- Complications of bone metastases, in general terms
- The vocabulary, in plain language
- Honest expectations with bone metastases
- How radiation helps painful bone metastases
- Living with bone metastases day to day
- How bone metastases are usually found and confirmed
- Bone-protecting medicines for metastases
- Support that helps alongside treatment
- What people assume about bone metastases
- Common questions about bone metastases
The short answer
What are bone metastases, and how are they treated?
Bone metastases are areas where breast cancer has spread to the bones. Bone is the most common place breast cancer spreads to, especially for hormone-sensitive cancers. The spine, pelvis, ribs, hips and the long bones of the arms and legs are most often affected. Bone metastases can cause pain, weaken bones so they break more easily, raise calcium levels in the blood, and occasionally press on the spinal cord. The cancer is still breast cancer, not bone cancer, and it is treated with whole-body breast cancer treatments such as hormone therapy, targeted drugs or chemotherapy, alongside bone-protecting medicines, radiation for painful areas and sometimes surgery to strengthen bones. Many women live for years with bone metastases and keep a good quality of life.
Why outlook is often better than other sites
When cancer has spread only to bone, it often responds well to treatment and can be controlled for a long time, though every situation is individual.
What treatment aims to do
Control the cancer, relieve pain, prevent fractures and complications, and help you stay active and independent.
When to seek urgent help
Back pain with leg weakness, numbness or bladder and bowel problems, sudden severe pain after a minor injury, or confusion and extreme thirst need emergency care.
This page gives general information only. Your oncologist will explain your own treatment plan.Treatments
How bone metastases are usually treated
Most people receive a combination of these approaches.
Whole-body treatment
Hormone therapy, targeted drugs or chemotherapy treat cancer throughout the body, including the bones.
Bone-protecting medicines
Given regularly to reduce fractures, pain and high calcium.
A dental check is advised first.Radiation
Targeted radiation often relieves pain in specific bones, sometimes in a single treatment.
Surgery
Used to strengthen a bone at high risk of breaking, or to repair a fracture or relieve pressure on the spine.
Also helpful
- Pain relief medicines
- Physiotherapy
- Palliative care support
Not sure whether this applies to you?
Ask an oncologistPossible complications
Complications of bone metastases, in general terms
Words you will hear
The vocabulary, in plain language
- Bone metastases
- Breast cancer that has spread to bone.
- Lytic lesions
- Areas where cancer has broken down bone.
- Sclerotic lesions
- Areas where bone has become abnormally dense.
- Pathological fracture
- A break in bone weakened by cancer.
- Hypercalcaemia
- High calcium in the blood, which can cause thirst and confusion.
- Palliative radiation
- Radiation given to relieve symptoms such as pain.
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Being straight with you
Honest expectations with bone metastases
Bone metastases mean breast cancer has become metastatic, which is generally not curable. At the same time, bone-only disease is often one of the more treatable forms of metastatic breast cancer, and many women live well for years.
Pain can usually be controlled
Radiation, medicines and treatment of the cancer relieve pain for most people. Tell your team if pain is not well controlled.
Fractures can often be prevented
Bone-protecting medicines and surgery for weakened bones reduce the chance of breaks.
Staying active is encouraged
With guidance about safe movements, exercise helps strength, mood and independence.
What this page cannot tell you
It cannot predict your own course. Ask your oncologist what to expect.
Radiation
How radiation helps painful bone metastases
Radiation is one of the most effective treatments for bone pain from metastases.
What it involves
Treatment is often short, sometimes a single session or a few sessions, aimed precisely at the painful area.
When pain eases
Pain often starts to improve within a few weeks. It may briefly worsen before it improves, which your team can help manage.
Focused radiation
For some people with limited spread, highly focused radiation can control individual bone metastases for longer.
Repeat treatment
If pain returns, radiation can sometimes be repeated to the same area.
Talk to our team
Have a question about your situation?
Call the helpline or leave your details, and someone will help you arrange a consultation at the CION centre nearest you. One helpline serves every CION centre.
Daily life
Living with bone metastases day to day
Practical steps help you stay safe and active.
Safe movement
Ask which movements to avoid, such as heavy lifting or twisting if the spine is affected. A physiotherapist can guide safe exercise.
Preventing falls
Clear floors, good lighting and supportive footwear reduce fracture risk.
Around the home
A chair with arms, a raised toilet seat and grab rails make sitting, standing and bathing safer and less painful when bones in the hips or spine are affected.
Managing pain
Take pain relief regularly as prescribed rather than waiting for pain to become severe, and report side effects.
Diagnosis
How bone metastases are usually found and confirmed
Bone metastases are often suspected because of symptoms, but sometimes they are picked up on scans done for another reason.
Symptoms that lead to tests
Persistent bone pain, particularly at night, a fracture after a minor fall, or symptoms of high calcium such as thirst, constipation and confusion often prompt investigation.
Scans
A bone scan shows areas of increased bone activity throughout the skeleton. CT and MRI give detailed pictures of particular areas, and PET-CT can show spread in bones and other organs together.
Blood tests
Calcium, alkaline phosphatase and kidney function tests help assess bone involvement and guide treatment.
Biopsy
Where it is safe, a sample from an affected bone confirms the diagnosis and rechecks hormone receptor and HER2 status, which can change from the original cancer and alter the choice of treatment.
Protecting the skeleton
Bone-protecting medicines for metastases
Bone-protecting medicines are an important part of treatment for most people with bone metastases.
What they do
They slow the bone breakdown that cancer triggers, lowering the chance of fractures, the need for radiation or surgery to bone, and high blood calcium.
How they are given
Usually as an infusion or an injection under the skin every few weeks, with calcium and vitamin D supplements and regular blood tests.
Dental care
Because of a rare risk of jaw bone problems, a dental check before starting and good mouth care throughout are advised.
Support
Support that helps alongside treatment
Living with bone metastases is easier with the right support around you.
Family and carers
Relatives often help with medicines, appointments and moving safely around the home. Involving them in conversations with your team helps everyone understand which movements to avoid, which symptoms need urgent attention, and how to support you without taking away your independence.
Work and finances
Treatment for bone metastases can continue for a long time. A social worker or financial counsellor can advise on leave, insurance and support schemes so costs and time off are easier to plan.
Palliative care
Specialist teams help with pain, sleep and mobility at any stage, not only near the end of life.
Physiotherapy and aids
Walking aids, back supports and advice on safe movement help you stay independent.
Emotional support
Counselling and support groups help patients and families adjust to living with metastatic breast cancer.
Commonly believed
What people assume about bone metastases
It is breast cancer that has spread, and it is treated as breast cancer.
Many women live for years with bone-only metastatic disease.
Guided activity is usually safe and helps strength and mood.
Radiation and medicines relieve pain for most people.
Questions we are asked
Common questions about bone metastases
How are bone metastases found?
Often through scans done because of bone pain or high calcium. Bone scans, CT, MRI or PET-CT show affected areas, and a biopsy may confirm them.
Will I need a biopsy?
Where possible, to confirm the diagnosis and recheck hormone and HER2 status.
Can I still exercise?
Usually yes, with guidance on safe movements.
What is spinal cord compression?
Pressure on the spinal cord causing back pain with leg weakness or numbness. It is an emergency.
How long do bone-protecting medicines continue?
Often for as long as they help, with regular reviews.
Can radiation be repeated?
Sometimes, depending on previous dose and area.
Does bone metastasis cause high calcium?
It can. Report thirst, confusion or constipation.
Who helps with pain?
Your oncology team and palliative care specialists.
17+ senior cancer specialists. One panel for your case.
Trained at AIIMS, Tata Memorial, and leading international centres. Combined 150+ years of experience. Every complex case is reviewed by 3+ of them — together.
Dr. C. Raghavendra Reddy
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Dr. Bharati Devi Gorantla
MBBS, MD(General Medicine), DM(Medical Oncology)(Adyar,Chennai), ECMO, MRCP SCE(UK)
Dr. Owais Mohammed
MBBS, MD (General Medicine), DrNB (Medical Oncology), ECMO, MRCP SCE (Medical Oncology) (UK)
Dr. Muralidhar Muddusetty
MBBS (AIIMS), MS (Surgery) (AIIMS), DNB (Surgical Oncology), MRCS (Edinburgh)
Dr. Vinay Mamidala
MBBS, MS(General Surgery), M.Ch(Surgical Oncology), FMAS, FARIS(Ongoing)
Dr. Vajja Sandeep Kumar
MBBS, MS (General Surgery), DrNB (Surgical Oncology), FALS Oncology
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Speak to a breast cancer specialist
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Sources
- Breast Cancer Now — Secondary breast cancer in the bone
- National Cancer Institute — Metastatic cancer: when cancer spreads
- European Society for Medical Oncology — Bone health in cancer clinical practice guideline
This page is general information, not a prescription. Do not change or stop any treatment based on what you read here. If anything is worrying you, contact your own treating team — or call our helpline and we will help you reach the right specialist.