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Fertility and menopause

Non-hormonal treatments for hot flushes

Hot flushes after breast cancer can be eased without HRT. Cooling and trigger avoidance, cognitive behavioural therapy, and several prescription medicine types have evidence of benefit. Some interact with hormone therapy, so choices are made carefully. This page explains the options.

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The short answer

What non-hormonal treatments help hot flushes after breast cancer?

Hot flushes are one of the most common and troublesome effects of breast cancer treatment, especially for women who go through sudden menopause or take hormone therapy. Because hormone replacement therapy is usually avoided after breast cancer, non-hormonal treatments are the main options. The good news is that several approaches have evidence of benefit, and many women find a combination works best. Lifestyle measures come first: dressing in layers, keeping cool, avoiding personal triggers such as hot drinks, spicy food, alcohol and stress, staying active and keeping a healthy weight. Psychological treatments, particularly cognitive behavioural therapy and clinical hypnosis, have good evidence for reducing how much hot flushes bother people and can also improve sleep and mood. Several prescription medicines can reduce the number and severity of hot flushes. These include certain antidepressants used at low doses, some nerve pain medicines, and a blood pressure medicine, each with its own benefits and side effects. Newer medicines that act on the brain's temperature control centre have also been developed. Some antidepressants can interact with certain hormone therapies, so your oncologist will choose carefully. Acupuncture helps some women, though evidence is mixed. Herbal remedies and supplements have limited evidence and may carry risks, so always check before using them.

Start with simple measures

Cooling, trigger avoidance and relaxation help many women.

Medicines can help

If symptoms affect daily life or sleep, ask about prescription options.

Check interactions

Tell your team about all medicines and supplements you take.

This page gives general information only. Your team will advise on treatments that suit you.

Approaches

Types of non-hormonal treatment

Combining approaches often works best.

Lifestyle changes

Cooling, trigger avoidance, exercise and healthy weight.

Psychological therapies

CBT and clinical hypnosis reduce the impact of flushes.

No medicine side effects.

Prescription medicines

Certain antidepressants, nerve pain medicines and others.

Complementary approaches

Acupuncture and relaxation techniques help some women.

Use caution with

  • Plant oestrogen supplements
  • Unregulated herbal products
  • Products that interact with treatment

Not sure whether this applies to you?

Ask an oncologist

Medicines compared

Prescription options, in general terms

Medicine type Key points
Certain antidepressants at low doses Reduce flushes for many women; some interact with certain hormone therapies
Nerve pain medicines Helpful for night sweats; may cause drowsiness or dizziness
A blood pressure medicine Modest benefit; dry mouth and low blood pressure can occur
Brain temperature-centre medicines Newer option; availability and suitability vary
Bladder medicine with flush benefit Sometimes considered; side effects need discussion

Words you will hear

The vocabulary, in plain language

Hot flush
A sudden feeling of heat, often with sweating and redness.
Vasomotor symptoms
Hot flushes and night sweats.
Cognitive behavioural therapy
A talking therapy that changes how you respond to symptoms.
Clinical hypnosis
Guided relaxation that can reduce hot flushes.
Drug interaction
When one medicine changes how another works.
Phytoestrogens
Plant substances that act like weak oestrogen.

Being straight with you

Honest realities of non-hormonal treatments

Non-hormonal treatments help many women, but it helps to have realistic expectations.

They reduce rather than remove flushes

Most treatments reduce the number or intensity of flushes rather than stopping them completely.

Side effects vary

Medicines can cause nausea, drowsiness, dry mouth or dizziness. Starting low and adjusting helps.

It may take trial and error

Finding the right treatment can take a few attempts.

Placebo effect is strong

Many studies show some improvement even with placebo, so evidence from trials matters.

What this page cannot tell you

It cannot choose a treatment for you. Your doctor can.

CBT

How cognitive behavioural therapy helps hot flushes

CBT is a practical, time-limited therapy with good evidence for menopause symptoms after breast cancer.

Understanding flushes

You learn what triggers flushes and how thoughts and stress can make them feel worse.

Paced breathing

Slow, deep breathing at the start of a flush can reduce its intensity.

Managing stress

Techniques to reduce stress help lower the frequency of flushes for some women.

Improving sleep

CBT also addresses sleep problems caused by night sweats.

Formats

CBT can be delivered individually, in groups, online or through self-help books.

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Everyday measures

Practical ways to stay cool

Small changes can make hot flushes easier to manage, especially in hot Indian weather.

Dress in layers

Choose loose cotton clothing you can remove quickly.

Carry a fan

A small handheld or battery fan and cool water help during a flush.

Keep your environment cool

Use fans, air conditioning where available, and light bedding.

Know your triggers

Keep a diary to identify triggers such as tea, coffee, spicy food or alcohol.

Stay active

Regular exercise may reduce flushes and improves mood and sleep.

Safety

Medicine interactions with hormone therapy

Some medicines for hot flushes can affect how hormone therapy works.

Why it matters

Certain antidepressants can reduce the activation of some hormone therapy tablets in the body, possibly making them less effective.

Choosing safely

Your oncologist or pharmacist will select a medicine less likely to interact.

Tell your team everything

Include over-the-counter medicines, herbal products and supplements.

Choosing

How you and your doctor choose a treatment

There is no single best treatment for hot flushes. The right choice depends on how severe your symptoms are, your other health conditions, the medicines you already take and what matters most to you.

How much flushes affect you

Mild flushes may be manageable with cooling and lifestyle changes. Frequent, severe flushes that disturb sleep, work or relationships often justify adding a medicine.

Your hormone therapy

Your oncologist will check for interactions, particularly if you take a tablet that blocks oestrogen, as some antidepressants can reduce its effect.

Other symptoms

If you also have low mood or anxiety, a medicine that helps both may be chosen. If night sweats and poor sleep are the main problem, a medicine taken at night may suit you.

Side effects you want to avoid

Tell your doctor if drowsiness, weight change or effects on blood pressure would be particularly difficult for you.

Starting low and reviewing

Medicines are usually started at a low dose and reviewed after a few weeks. If one does not help, another can be tried.

Keeping a symptom diary

Recording how many flushes you have and how severe they are helps you and your doctor judge whether a treatment is working.

Stopping treatment

Some medicines need to be reduced gradually rather than stopped suddenly. Ask your doctor before stopping.

Supplements

Herbal remedies and supplements for hot flushes

Many products are marketed for menopause, but few have good evidence after breast cancer.

Plant oestrogens

Soy isoflavone and red clover supplements contain plant oestrogens, and their safety after breast cancer is uncertain.

Black cohosh and evening primrose

These are commonly sold for hot flushes, but studies show little benefit, and rare liver problems have been reported with some products.

Buying safely

Products bought online or from unregulated sellers may contain undeclared ingredients. Always show supplements to your pharmacist or oncologist before starting them.

Vitamin E and flaxseed

These have been studied for hot flushes, with little or no benefit shown compared with placebo in most trials, so they are not usually recommended.

Keep a list

Write down every supplement you take and share it at each appointment.

Other herbs

Some herbal remedies can affect the liver or interact with cancer medicines.

Commonly believed

What people assume about hot flush treatments

Antidepressants for flushes mean you are depressed.

Low doses reduce flushes whether or not you are depressed.

Natural supplements are always safe.

Some contain plant oestrogens or interact with treatment.

Nothing helps without HRT.

Several non-hormonal treatments have good evidence.

Talking therapy cannot help physical symptoms.

CBT reduces the impact of hot flushes and night sweats.

Questions we are asked

Common questions about non-hormonal hot flush treatments

Which treatment works best?

It varies. Many women use a combination of lifestyle changes, CBT and medicine.

How quickly do medicines work?

Often within a few weeks.

Can I take these with hormone therapy?

Many can, but some interact. Your team will check.

Is acupuncture safe?

Usually, with a qualified practitioner; avoid the at-risk arm.

Are soy foods helpful?

Evidence is limited; normal dietary amounts are generally fine.

Will flushes stop eventually?

For many women they lessen over time.

Can I get CBT in India?

Yes, through psychologists, hospitals and online services.

Who can prescribe treatment?

Your oncologist, gynaecologist or family doctor.

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Sources

  1. North American Menopause Society — Nonhormone therapy position statement
  2. National Cancer Institute — Hot flashes and night sweats (PDQ)
  3. Breast Cancer Now — Menopausal symptoms and breast cancer

This page is general information, not a prescription. Do not change or stop any treatment based on what you read here. If anything is worrying you, contact your own treating team — or call our helpline and we will help you reach the right specialist.

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