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Arsenic in groundwater: what it means for your liver | CION Cancer Clinics

Arsenic in borewell or hand-pump water can raise the risk of liver cancer, but it is a far smaller cause than hepatitis B, hepatitis C, alcohol or fatty liver. Its clearest links are with skin, bladder and lung cancer. Unlike most risks, it can be changed. This page explains what arsenic does, how to get your water tested, and what to tell your doctor. At CION Cancer Clinics, our specialists help you understand your own risk and plan regular liver checks that fit it.

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Medically reviewed by Dr. Naresh GunduConsultant Medical Oncologist · MBBS, DNB (Internal Medicine), DM (Medical Oncology, AIIMS) · last reviewed October 2026, next review due October 2027
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The short answer

Can arsenic in well water cause liver cancer?

Yes, it can, but it is a less common cause than hepatitis B, hepatitis C, alcohol or fatty liver. Drinking water with high arsenic for many years is firmly linked to cancers of the skin, bladder and lung. The link with the liver is real but weaker, and it is strongest for a rare liver cancer called angiosarcoma.

Where the arsenic comes from

Arsenic is a natural part of some rocks. In certain areas it dissolves into the water held deep underground, so a borewell or hand pump can draw it up. You cannot see, smell or taste it. Water that looks perfectly clear can still carry it, and only a test will tell you.

Why this page matters even if your risk is low

Unlike your genes or your age, the water your family drinks can be changed. That makes arsenic one of the few liver cancer risks you can do something about this week. If you already have a liver scan report, this page is about the cause of primary liver cancer, which starts in the liver. Cancer that spread to the liver from elsewhere is explained on primary versus secondary liver cancer.

Arsenic is one risk among several. Hepatitis B remains the biggest single cause of liver cancer in India.

What arsenic does

How does arsenic harm the liver and the rest of the body?

Arsenic does its damage slowly. Most of the harm comes from drinking it every day for many years, not from one glass.

The skin shows it first

Long exposure often leaves dark and pale spots on the chest and back, and hard, rough patches on the palms and soles. Doctors treat these changes as a warning that the whole body has been exposed.

The liver can scar

Arsenic can damage the small blood vessels inside the liver. Over time this can raise the pressure in the portal vein, the large vein carrying blood from the gut to the liver, even when there is no cirrhosis.

Signs this has happened

  • An enlarged spleen on a scan
  • Swelling of the abdomen with fluid
  • Swollen veins in the food pipe, found on endoscopy

Cancer risk rises in several organs

Inorganic arsenic is classed as a cause of cancer in people. The skin, bladder and lung carry the clearest risk. The liver, kidney and prostate are also linked, though the evidence is thinner.

Other illness comes with it

Long exposure is also tied to heart and blood vessel disease and to diabetes. Diabetes in turn raises the risk of fatty liver, which adds to liver cancer risk by a separate road.

Not sure whether this applies to you?

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What you can do

How do I find out if our water has arsenic, and what then?

Find out where your drinking water really comes from

Piped water from a treated government supply is tested by the supplier. A private borewell, an open well or a village hand pump is usually not tested unless someone asks.

Ask for a water test

Your panchayat, municipal office or the district rural water supply department can tell you whether arsenic has been found in your area and where a sample can be tested. Private laboratories also test water. Ask specifically for arsenic, because a routine test may not include it.

If the result is high, change what you drink and cook with

Switch drinking and cooking water to a safe source. Boiling does not remove arsenic. It concentrates it as the water evaporates. Some household filters designed for arsenic do work, but only if they are maintained as the maker says.

Tell your doctor about the exposure

Mention how long the family drank that water. If anyone has the skin changes described above, or already has liver disease, the doctor may suggest a liver scan and blood tests.

Keep up any liver checks you were already advised

If you have hepatitis B, hepatitis C or cirrhosis, arsenic is an extra reason to stay on the six-monthly checks explained in who needs liver cancer screening.

Words you may hear

What do the terms on a water or liver report mean?

Inorganic arsenic
The harmful form found in groundwater. It is the form linked to cancer, and the one a water test measures.
Arsenicosis
Illness caused by long exposure to arsenic. It usually shows first as skin spots and thick patches on the hands and feet.
Angiosarcoma of the liver
A rare cancer of the blood vessel lining inside the liver. It is the liver cancer most clearly linked with arsenic and certain industrial chemicals.
Hepatocellular carcinoma (HCC)
The commonest primary liver cancer, starting in the main liver cells. Its link with arsenic is less certain than its link with hepatitis.
Non-cirrhotic portal hypertension
Raised pressure in the portal vein without cirrhosis. Long arsenic exposure is one known cause.

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Commonly believed

What do families get wrong about arsenic in water?

"Our water is sweet and clear, so it is safe."

Arsenic has no taste, colour or smell. Clear, sweet water from a deep borewell can still carry it. Only a laboratory or a proper field kit can tell you.

"Boiling the water will remove it."

Boiling kills germs, not arsenic. As water boils away, the arsenic left behind becomes more concentrated. A safe source or a filter built for arsenic is what helps.

"We have drunk it for years, so the damage is done and changing is pointless."

Stopping exposure still helps. Risk builds with the total amount taken in over a lifetime, so every year of safer water counts. Skin changes can also settle after the exposure stops.

"If someone in the family got liver cancer, it must be the water."

Usually it is not. Hepatitis B, hepatitis C, alcohol and fatty liver cause far more liver cancer. Each of these should be checked, because some of them affect other family members too.

Being straight with you

What this page cannot tell you

It cannot tell you whether the water in your village or colony has arsenic. Levels can differ between two borewells in the same street, and only a test answers that. It also cannot tell you whether a cancer in your family was caused by water. Doctors can rarely pin one cancer on one cause, and most people with liver cancer have more than one risk.

Who this does not apply to

If your household drinks treated piped water, or water already tested and found safe, arsenic is very unlikely to be your concern. Your time is better spent checking for hepatitis B and C and looking after your weight and drinking, as set out in lowering your liver cancer risk.

Who can help

Your local water authority can test the water. A physician or hepatologist can examine the skin and order liver tests. If a liver scan has already shown something, a CION oncologist can review the report with you and, where needed, CION arranges further scans through accredited diagnostic partners.

Evidence on arsenic and the commonest liver cancer is still limited. We say so plainly rather than overstate it.

Questions we are asked

Common questions about arsenic and liver cancer

Is arsenic in groundwater a problem in Telangana and Andhra Pradesh?

The best-known arsenic belt in India lies along the eastern Ganga and Brahmaputra plains. Telangana and Andhra are better known for fluoride in groundwater, though arsenic has been reported in some pockets. The only way to know about your own well is to test it, whatever the district.

Does an RO filter remove arsenic?

A well-maintained reverse osmosis unit removes much of the arsenic in water, and some filters are made specifically for arsenic. Candle, cloth and sand filters do not. Any filter stops working properly if the parts are not changed on time, so retest the filtered water once it is in use.

Can rice grown with arsenic water add to the risk?

Rice takes up arsenic from contaminated irrigation water more than most crops. Washing rice well and cooking it in plenty of safe water, then draining the extra, lowers the amount. In most households, drinking water is still the bigger source to fix first.

Is there a blood test for arsenic?

Urine tests show recent exposure. Hair and nail tests show exposure over a longer stretch. A doctor will decide which, if any, is useful. None of them can tell you whether you will get cancer, so testing the water is usually the more useful first step.

Should someone exposed to arsenic have liver cancer screening?

Arsenic exposure on its own is not a standard reason for regular liver cancer screening. Screening is advised mainly for people with cirrhosis or certain kinds of hepatitis B. If you have arsenic skin changes or an enlarged spleen, ask your doctor whether a liver scan makes sense for you.

Are children more at risk?

Children drink more water for their body size, and exposure early in life is linked to more illness later. That makes safe water for children a priority. It does not mean a child exposed in the past is bound to become ill, and switching the water now still helps.

Is arsenic in some traditional medicines the same problem?

It is the same metal, and some traditional preparations have been found to contain heavy metals. Tell your doctor everything you take, without worrying about being judged. This is covered in more detail on heavy metals in traditional medicines.

Who should I call if I am worried about a liver report?

If a scan or blood test has already shown a liver problem, call the CION helpline. A CION oncologist can go through the report with you, explain what it means, and help plan any further scans, which CION arranges through accredited diagnostic partners.

Your Specialists

Meet CION's liver cancer specialists. Bring your scan reports and liver blood tests.

Our medical and surgical oncologists plan liver cancer care together, weighing the tumour and how well your liver works before choosing surgery, a liver-directed procedure or medicines.

Dr. Naresh Gundu
Medical Oncologist

Dr. Naresh Gundu

MBBS, DNB (Internal Medicine), DM (Medical Oncology)

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Dr. C. Raghavendra Reddy
Medical Oncologist

Dr. C. Raghavendra Reddy

MBBS(Gold Medal), DNB(General Medicine), DM(Medical Oncology)(Gold Medal)

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Dr. Bharati Devi Gorantla
Medical Oncologist

Dr. Bharati Devi Gorantla

MBBS, MD(General Medicine), DM(Medical Oncology)(Adyar,Chennai), ECMO, MRCP SCE(UK)

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Dr. Owais Mohammed
Medical Oncologist

Dr. Owais Mohammed

MBBS, MD (General Medicine), DrNB (Medical Oncology), ECMO, MRCP SCE (Medical Oncology) (UK)

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Dr. T. Raghavender Reddy
Medical Oncologist

Dr. T. Raghavender Reddy

MBBS, DM (Medical Oncology), MD (Radiation Oncology)

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Dr. N. Kiranmayee
Medical Oncologist

Dr. N. Kiranmayee

MBBS, DM (Medical Oncology), MD (Internal Medicine)

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Dr. Muralidhar Muddusetty
Surgical Oncologist

Dr. Muralidhar Muddusetty

MBBS (AIIMS), MS (Surgery) (AIIMS), DNB (Surgical Oncology), MRCS (Edinburgh)

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Dr. Mohammed  Imaduddin
Surgical Oncologist

Dr. Mohammed Imaduddin

M.B.B.S, MS (General Surgery), M.Ch (Surgical Oncology)

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Sources

  1. World Health Organization — Arsenic
  2. American Cancer Society — Arsenic and Cancer Risk
  3. American Cancer Society — Liver Cancer Risk Factors
  4. National Cancer Institute — Liver Cancer Causes, Risk Factors, and Prevention

This page is general information, not a prescription. Do not change or stop any treatment based on what you read here. If anything is worrying you, contact your own treating team — or call our helpline and we will help you reach the right specialist.

Talk to us

Worried about a liver report after years on well water?

Tell us what the scan or blood test showed and how long the family drank that water. A CION oncologist can go through it with you and help plan any next tests. One helpline serves every CION centre.

Call 1800 202 8726

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Where to find us

Our centres in and around Hyderabad

Addressed by landmark, because that is how this city navigates. One helpline books a consultation at any of these centres, and your team will tell you where each test and operation takes place.

CION Ameerpet

Beside Blue Fox Hotel, Satyam Theatre Road

Begumpet SR Nagar Punjagutta
CION Kukatpally

Opposite Big Bazaar, Mumbai Highway

KPHB JNTU Bharat Nagar
CION L.B. Nagar

Anu Arcade, next to L.B. Nagar Metro station

Vanasthalipuram Nagole Hayathnagar
CION Tolichowki

Inside Premier Hospital, Khader Bagh Road

Mehdipatnam Attapur Rethibowli
CION Masab Tank

Mahavir Hospital, AC Guards, Lakdikapul

Lakdikapul Khairatabad Basheer Bagh
CION Banjara Hills

Road No. 12

Jubilee Hills Madhapur Film Nagar
CION Kompally

Suchitra Circle, NH-44

Suchitra Circle Alwal Dundigal
CION Balanagar

Balanagar Main Road

Balanagar Fatehnagar Moosapet
CION Siddipet

Lohith Sai Hospital, Shivaji Nagar

Gajwel Husnabad Dubbaka
CION Sangareddy

X Roads, Pothreddipalle

Narayankhed Zaheerabad Patancheru
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Liver Cancer Topics

Browse CION’s liver cancer guide — hepatitis and fatty liver, surveillance, symptoms and scans, staging and liver function, surgery, transplant, TACE and medicines, living with it, cost and care in Hyderabad. Tap any topic to read more.

Understanding liver cancer

Hepatitis B and liver cancer

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Symptoms and early signs

Early signs of liver cancer: what they are and what they usually mean Does early liver cancer have symptoms? Usually not, and here is why Pain in the upper right abdomen: is it the liver, and is it cancer? Can right shoulder blade pain mean liver cancer? A lump or fullness under the right ribs: is it the liver? Unexplained weight loss: could it be liver cancer? Loss of appetite and feeling full quickly: is it the liver? Nausea and vomiting: when it could be the liver Yellow eyes and skin: when jaundice means cancer Itching all over the body: when is it the liver? Dark urine and pale stools: what they mean and when to worry Swollen or bloated abdomen: when is it the liver? Swollen legs and feet: when is it the liver? Extreme tiredness and weakness: could it be the liver? Fever with no obvious infection: could it be liver cancer? Easy bruising and bleeding gums: is it my liver? Confusion, drowsiness and odd behaviour: could it be the liver? Spider-like veins on the chest and red palms: are they a liver sign? Prominent veins on the abdomen: when do they point to the liver? Breast enlargement in men: is it the liver? Vomiting blood or passing black stools: go to hospital now Raised liver enzymes on a routine blood test: what SGPT and SGOT mean Is it liver cancer or gallstones? How the symptoms differ Is it liver cancer, or acidity and gas? Liver symptoms that need an appointment this week, and which cannot wait A liver symptom checklist to take to your doctor Liver cancer symptoms, with the Telugu words families use

Liver resection (surgery)

Liver transplant for cancer

Liver transplant for liver cancer: who it is for Why a liver transplant can treat both the cancer and the cirrhosis The Milan criteria for liver transplant in liver cancer, explained Beyond the Milan criteria: UCSF and extended rules for liver transplant Who cannot have a liver transplant for liver cancer? Living donor liver transplant in India, explained Who can be a living liver donor in India? What happens to the donor: risks and recovery after living liver donation Blood group matching for a liver transplant donor Deceased donor liver transplant and the waiting list in India Jeevandan: how Telangana's organ donation programme works for liver cancer How to register on the liver transplant waiting list in Telangana How long is the wait for a liver transplant, and what decides priority? MELD exception points: how liver cancer is weighed on a transplant list Staying eligible: treatment while you wait for a liver transplant Dropping off the transplant list: why it happens and what comes next Downstaging liver cancer to become eligible for a transplant The transplant assessment: every test you will have The psychological and social assessment before a liver transplant Alcohol abstinence before a liver transplant: what centres ask for The liver transplant operation: what actually happens Intensive Care and the First Week After a Liver Transplant Immunosuppression for Life: What It Means Day to Day Liver transplant rejection: the signs and what is done Infection risk after a liver transplant, and how to reduce it Can liver cancer come back after a transplant? New cancers after a liver transplant: the risk and the checks Liver transplant cost in India and in Hyderabad: what makes up the bill Insurance and scheme cover for a liver transplant Life after a liver transplant: what normal looks like Liver transplant myths in Indian families, and what is true A liver transplant guide for Telugu-speaking families

Systemic therapy decisions

Diet and nutrition

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Alternative and Ayurvedic liver treatments

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Cost, insurance and schemes

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Liver cancer in Hyderabad

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