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The liver cancer pathway from first scan to treatment | CION Cancer Clinics

Most people go from a first scan, to a detailed liver CT or MRI, to blood tests that measure liver function, to a tumour board that agrees the plan, and then to treatment. Many different doctors are involved, and each handover is where delays creep in. This page sets out the usual order, who does what, and how to stop a step from stalling. At CION Cancer Clinics, our team supports patients and families through symptoms, follow-up and life during and after treatment.

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Medically reviewed by Dr. Naresh GunduConsultant Medical Oncologist · MBBS, DNB (Internal Medicine), DM (Medical Oncology, AIIMS) · last reviewed October 2026, next review due October 2027
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The short answer

What happens between the first scan and the first treatment?

The pathway usually runs from a first scan, to a detailed liver scan, to blood tests that measure how well the liver works, to a team meeting that agrees the plan, and then to treatment. Each step answers one question, and the plan is only as good as the answers it is built on.

Which liver cancer this page is about

This page follows cancer that starts in the liver, mostly hepatocellular carcinoma (HCC). If you were told the cancer spread to the liver from the bowel, breast or elsewhere, the pathway is planned around where it started. Our page on primary and secondary liver cancer explains the difference.

Why it feels so fragmented

Few cancers pass through as many hands. A physician, a gastroenterologist, a hepatologist, a radiologist, an interventional radiologist, an oncologist and sometimes a transplant surgeon may all be involved. Each handover is where reports get lost and weeks slip by. Knowing the order of steps helps you notice when one has stalled.

The pathway is a map, not a timetable. Your team may skip or repeat a step for good reason.

The people involved

Which doctors will I meet along the way?

Not everyone sees all of them. These are the roles most people meet.

The doctor who found it

Often a general physician or gastroenterologist who ordered an ultrasound for pain, a check-up or a hepatitis follow-up. They make the first referral, so their letter matters.

Hepatologist

A liver specialist. They judge how well the liver works, look for cirrhosis and varices, and treat hepatitis B or C. Their view decides which treatments the liver can tolerate.

Radiologist and interventional radiologist

The radiologist reads the scans. The interventional radiologist treats through needles and fine tubes, with procedures such as TACE and ablation.

Oncologist and surgeon

The medical oncologist plans drug treatment and often coordinates the whole plan. The surgical oncologist assesses whether part of the liver can be removed.

Sometimes also

  • A transplant surgeon at a licensed transplant centre
  • A radiation oncologist
  • A palliative care doctor for symptoms

Not sure whether this applies to you?

Ask an oncologist

Step by step

What is the usual order of tests and decisions?

A first scan raises the question

Usually an ultrasound shows a spot or lesion. It cannot say what the spot is. It only says it needs a closer look.

A detailed liver scan

A triple-phase CT or liver MRI shows how the spot takes up contrast. In a liver with cirrhosis, the pattern can be enough to diagnose HCC without a biopsy.

Blood tests and hepatitis checks

Liver function, AFP, platelets, INR and hepatitis B and C tests. These show how well the liver works and what may have caused the cancer.

A biopsy, only if needed

If the scan pattern is not clear, or the liver is not cirrhotic, a needle biopsy may be arranged.

Staging and the tumour board

The team combines the tumour, liver function and your fitness into a BCLC stage, then discusses the case together.

Treatment begins

Surgery, ablation, TACE, transplant assessment, radiation or drug treatment, depending on the stage and the liver.

On the way

Words you will hear at each step

Lesion or SOL
A spot or space-occupying lesion on a scan. The word describes something seen, not what it is.
Arterial enhancement and washout
How a spot lights up with contrast and then fades. Together they are the pattern that suggests HCC.
LI-RADS
A scale radiologists use to say how likely a spot is to be HCC.
Child-Pugh
A score, A to C, for how well the liver is working.
BCLC stage
The staging system that links the tumour, the liver and your fitness to the treatment options.
Tumour board
A meeting where specialists review the scans and reports together and agree a plan.

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Did you know

At CION, liver cases are discussed at a multidisciplinary tumour board before a plan is confirmed. Scans, biopsies, TACE, ablation and transplant assessment are coordinated through accredited partner hospitals and diagnostic centres, so the board can see every result in one place.

Commonly believed

Four things families expect about the pathway

"Nothing can happen until there is a biopsy."

In a liver with cirrhosis, HCC can often be diagnosed from a good-quality scan alone. Waiting for a biopsy that is not needed can add delay. Our page on diagnosis without a biopsy explains when this applies.

"The first scan we had is enough for the specialist."

A plain ultrasound or a single-phase CT rarely answers the question. Most teams need a liver-protocol CT or MRI before they can stage the cancer.

"Treatment depends only on the size of the tumour."

The liver around the tumour matters just as much. Two people with the same tumour can be offered different treatment because one liver is working well and the other is not.

"Seeing more doctors means more delay."

Each specialist answers a different question. Delay usually comes from reports not reaching the next doctor, not from the number of doctors. A single file and a tumour board review shorten the gaps.

Being straight with you

What this page cannot tell you

It cannot tell you which step you are on, or whether a spot on your scan is cancer. Only the team that has your scans, blood tests and history can do that. It also cannot say how long each step should take where you are being seen. Our page on where delays happen covers the common hold-ups and what helps.

Who this does not apply to

Cancer that has spread to the liver from another organ follows the pathway of that cancer. Children with liver tumours are cared for on a separate path, described on our hepatoblastoma page. Someone who is very unwell, with jaundice, confusion or bleeding, may need hospital care before any of these steps.

What helps at every step

Carry every report and the scan images in one place, as described in keeping a single liver cancer file. Ask at each visit what the next step is and who will arrange it. If nobody can answer, ask for your case to be reviewed by a tumour board.

Questions we are asked

Common questions about the liver cancer pathway

Who should coordinate the whole pathway?

Ideally one named doctor, often the medical oncologist or hepatologist, who keeps track of every result and makes sure the next step is booked. If you are passing between several doctors and nobody holds the full picture, ask which of them will act as your lead.

Do I always need a biopsy before treatment?

No. In a liver with cirrhosis, a clear pattern on a liver-protocol CT or MRI can be enough to diagnose HCC. A biopsy is arranged when the scan is not typical, when the liver is not cirrhotic, or when another type of cancer is suspected.

Why do they test for hepatitis when the problem is cancer?

Hepatitis B and C are common causes of liver cancer in India. Treating the virus protects the rest of the liver, and hepatitis B can flare during some cancer treatments if it is not controlled. The result also matters for screening family members.

Why do I need an endoscopy?

People with cirrhosis can have swollen veins in the food pipe, called varices, which can bleed. Checking for them before some treatments allows them to be treated first. It is arranged through a gastroenterologist or hepatologist.

What is a tumour board and do I attend it?

It is a meeting where several specialists review your scans and reports together and agree a plan. Patients do not usually attend. Your doctor explains the recommendation afterwards and talks it through with you and your family.

Can I get a second opinion partway through?

Yes, at any step. A second opinion is most useful once the detailed scan and blood tests are done, because the reviewing team can then see the whole picture. Bring the scan images, not just the written reports.

Where does treatment actually take place?

It depends on the treatment. Drug treatments are given at CION centres. Procedures such as TACE, ablation, surgery, radiation and transplant are coordinated through accredited partner hospitals, and your team will tell you exactly where each one takes place.

We live outside Hyderabad. Can some steps happen nearer home?

Often, yes. Blood tests and some scans can be done near home if the quality is suitable, and results shared with the team. Call the helpline to check what can be done locally before you travel. One helpline serves every CION centre.

Your Specialists

Meet CION's liver cancer specialists. Bring your scan reports and liver blood tests.

Our medical and surgical oncologists plan liver cancer care together, weighing the tumour and how well your liver works before choosing surgery, a liver-directed procedure or medicines.

Dr. Naresh Gundu
Medical Oncologist

Dr. Naresh Gundu

MBBS, DNB (Internal Medicine), DM (Medical Oncology)

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Dr. C. Raghavendra Reddy
Medical Oncologist

Dr. C. Raghavendra Reddy

MBBS(Gold Medal), DNB(General Medicine), DM(Medical Oncology)(Gold Medal)

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Dr. Bharati Devi Gorantla
Medical Oncologist

Dr. Bharati Devi Gorantla

MBBS, MD(General Medicine), DM(Medical Oncology)(Adyar,Chennai), ECMO, MRCP SCE(UK)

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Dr. Owais Mohammed
Medical Oncologist

Dr. Owais Mohammed

MBBS, MD (General Medicine), DrNB (Medical Oncology), ECMO, MRCP SCE (Medical Oncology) (UK)

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Dr. T. Raghavender Reddy
Medical Oncologist

Dr. T. Raghavender Reddy

MBBS, DM (Medical Oncology), MD (Radiation Oncology)

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Dr. N. Kiranmayee
Medical Oncologist

Dr. N. Kiranmayee

MBBS, DM (Medical Oncology), MD (Internal Medicine)

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Dr. Muralidhar Muddusetty
Surgical Oncologist

Dr. Muralidhar Muddusetty

MBBS (AIIMS), MS (Surgery) (AIIMS), DNB (Surgical Oncology), MRCS (Edinburgh)

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Dr. Mohammed  Imaduddin
Surgical Oncologist

Dr. Mohammed Imaduddin

M.B.B.S, MS (General Surgery), M.Ch (Surgical Oncology)

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Want a specific doctor for your case? Mention them when booking.

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Sources

  1. National Cancer Institute — Liver Cancer Diagnosis
  2. American Cancer Society — Diagnosing Liver Cancer
  3. American Cancer Society — Treatment of Liver Cancer, by Stage
  4. Cancer Research UK — Diagnosing liver cancer

This page is general information, not a prescription. Do not change or stop any treatment based on what you read here. If anything is worrying you, contact your own treating team — or call our helpline and we will help you reach the right specialist.

Talk to us

Not sure what the next step should be?

Share the reports you have and we will tell you which step you are on and what is still needed before a plan can be made. One helpline serves every CION centre.

Call 1800 202 8726

Speak to an oncologist

Where to find us

Our centres in and around Hyderabad

Addressed by landmark, because that is how this city navigates. One helpline books a consultation at any of these centres, and your team will tell you where each test and operation takes place.

CION Ameerpet

Beside Blue Fox Hotel, Satyam Theatre Road

Begumpet SR Nagar Punjagutta
CION Kukatpally

Opposite Big Bazaar, Mumbai Highway

KPHB JNTU Bharat Nagar
CION L.B. Nagar

Anu Arcade, next to L.B. Nagar Metro station

Vanasthalipuram Nagole Hayathnagar
CION Tolichowki

Inside Premier Hospital, Khader Bagh Road

Mehdipatnam Attapur Rethibowli
CION Masab Tank

Mahavir Hospital, AC Guards, Lakdikapul

Lakdikapul Khairatabad Basheer Bagh
CION Banjara Hills

Road No. 12

Jubilee Hills Madhapur Film Nagar
CION Kompally

Suchitra Circle, NH-44

Suchitra Circle Alwal Dundigal
CION Balanagar

Balanagar Main Road

Balanagar Fatehnagar Moosapet
CION Siddipet

Lohith Sai Hospital, Shivaji Nagar

Gajwel Husnabad Dubbaka
CION Sangareddy

X Roads, Pothreddipalle

Narayankhed Zaheerabad Patancheru
Explore more

Liver Cancer Topics

Browse CION’s liver cancer guide — hepatitis and fatty liver, surveillance, symptoms and scans, staging and liver function, surgery, transplant, TACE and medicines, living with it, cost and care in Hyderabad. Tap any topic to read more.

Understanding liver cancer

Hepatitis B and liver cancer

How hepatitis B leads to liver cancer, and what lowers the risk I am a hepatitis B carrier: what is my liver cancer risk? HBsAg positive: what it actually means for your liver Reading a hepatitis B report: HBsAg, HBeAg, anti-HBs and anti-HBc Hepatitis B viral load: why the number matters for liver cancer risk Inactive carrier or active hepatitis B: what is the difference? Can hepatitis B cause liver cancer without cirrhosis? Antiviral treatment lowers liver cancer risk, but does not remove it Why you still need liver scans even on antiviral treatment Stopping hepatitis B medicine: why it is risky and what to do instead How hepatitis B spreads, and how it does not Hepatitis B and pregnancy: how to protect your baby Mother-to-child hepatitis B and the birth-dose vaccine Should my family be tested for hepatitis B? Vaccinating the household of a hepatitis B carrier The hepatitis B vaccine in India: schedule, cost and boosters Hepatitis B vaccination is liver cancer prevention Do I need a booster? Checking whether the hepatitis B vaccine worked Hepatitis B and marriage: the questions nobody asks out loud Hepatitis B and your job: what you do and do not have to disclose Hepatitis B reactivation during cancer treatment: how to prevent it Hepatitis D: the infection that makes hepatitis B worse Occult hepatitis B: what a positive anti-HBc with a negative HBsAg means Hepatitis B in Telangana and Andhra Pradesh: how common it is and what families can do Where to get tested for hepatitis B in Hyderabad Hepatitis B: what to tell your children Hepatitis B myths in Telugu families, and what is actually true A hepatitis B guide for Telugu families

Symptoms and early signs

Early signs of liver cancer: what they are and what they usually mean Does early liver cancer have symptoms? Usually not, and here is why Pain in the upper right abdomen: is it the liver, and is it cancer? Can right shoulder blade pain mean liver cancer? A lump or fullness under the right ribs: is it the liver? Unexplained weight loss: could it be liver cancer? Loss of appetite and feeling full quickly: is it the liver? Nausea and vomiting: when it could be the liver Yellow eyes and skin: when jaundice means cancer Itching all over the body: when is it the liver? Dark urine and pale stools: what they mean and when to worry Swollen or bloated abdomen: when is it the liver? Swollen legs and feet: when is it the liver? Extreme tiredness and weakness: could it be the liver? Fever with no obvious infection: could it be liver cancer? Easy bruising and bleeding gums: is it my liver? Confusion, drowsiness and odd behaviour: could it be the liver? Spider-like veins on the chest and red palms: are they a liver sign? Prominent veins on the abdomen: when do they point to the liver? Breast enlargement in men: is it the liver? Vomiting blood or passing black stools: go to hospital now Raised liver enzymes on a routine blood test: what SGPT and SGOT mean Is it liver cancer or gallstones? How the symptoms differ Is it liver cancer, or acidity and gas? Liver symptoms that need an appointment this week, and which cannot wait A liver symptom checklist to take to your doctor Liver cancer symptoms, with the Telugu words families use

Liver resection (surgery)

Liver transplant for cancer

Liver transplant for liver cancer: who it is for Why a liver transplant can treat both the cancer and the cirrhosis The Milan criteria for liver transplant in liver cancer, explained Beyond the Milan criteria: UCSF and extended rules for liver transplant Who cannot have a liver transplant for liver cancer? Living donor liver transplant in India, explained Who can be a living liver donor in India? What happens to the donor: risks and recovery after living liver donation Blood group matching for a liver transplant donor Deceased donor liver transplant and the waiting list in India Jeevandan: how Telangana's organ donation programme works for liver cancer How to register on the liver transplant waiting list in Telangana How long is the wait for a liver transplant, and what decides priority? MELD exception points: how liver cancer is weighed on a transplant list Staying eligible: treatment while you wait for a liver transplant Dropping off the transplant list: why it happens and what comes next Downstaging liver cancer to become eligible for a transplant The transplant assessment: every test you will have The psychological and social assessment before a liver transplant Alcohol abstinence before a liver transplant: what centres ask for The liver transplant operation: what actually happens Intensive Care and the First Week After a Liver Transplant Immunosuppression for Life: What It Means Day to Day Liver transplant rejection: the signs and what is done Infection risk after a liver transplant, and how to reduce it Can liver cancer come back after a transplant? New cancers after a liver transplant: the risk and the checks Liver transplant cost in India and in Hyderabad: what makes up the bill Insurance and scheme cover for a liver transplant Life after a liver transplant: what normal looks like Liver transplant myths in Indian families, and what is true A liver transplant guide for Telugu-speaking families

Systemic therapy decisions

Diet and nutrition

Diet in liver cancer: what actually matters Why eating enough protein is the priority in liver cancer The protein myth: why 'rest the liver' advice is wrong How much protein, and from which Indian foods? Dal, paneer, egg and curd: a practical protein plan for liver cancer Vegetarian and vegan protein with cirrhosis and liver cancer The late-night snack that helps a damaged liver Small frequent meals: why long gaps hurt a damaged liver Salt in liver cancer: the rules, and when they apply Fluid and water with liver cancer: how much is right? Foods to avoid with liver cancer, and what to keep eating Raw fish, raw shellfish and liver disease: what is safe to eat Iron, turmeric and the supplements that can harm a damaged liver Is turmeric good or bad for the liver when you have liver cancer? Sugar, jaggery and diabetes when you have liver cancer Oil and ghee with liver cancer: how much is reasonable? Chicken, mutton and fish with liver cancer: what is safe to eat? Eating when nothing tastes right with liver cancer Eating with a swollen abdomen: what to do when you feel full too soon Weight loss and muscle loss in liver cancer: how to slow it Nutrition supplements and protein powders in liver cancer: which and when Feeding tubes in liver cancer: when they are considered Coffee and the liver: what the evidence says Exercise with liver cancer and cirrhosis: is it safe, and what helps? A Telugu diet plan for liver cancer: one day of meals, built on protein A week of low-salt, high-protein Telugu meals for liver cancer

Alternative and Ayurvedic liver treatments

Ayurvedic and herbal treatment for liver cancer: an honest look Why the liver is the organ most harmed by herbal remedies Herb-induced liver injury: the signs, the risk and what to do Liver detox and liver cleansing: what they actually do Hepatoprotective tonics and syrups sold for the liver Milk thistle and silymarin: what the evidence shows Kalmegh, bhumi amla and punarnava: what the evidence shows for the liver Papaya leaf juice for low platelets in liver cancer: an honest look Wheatgrass and juice therapies in liver cancer: what the evidence shows Giloy and the liver injury reports: what they mean for a damaged liver Ashwagandha, garcinia and green tea extract: can they injure the liver? Heavy metals in some traditional preparations: what liver patients should know Homeopathy for liver cancer: what the evidence shows Cow urine, gaumutra and liver cancer: what the claims rest on Cannabis and CBD oil for liver cancer: what helps, what harms and the law in India Apricot kernels, laetrile and other imported cancer claims: the real danger Alkaline diets and starving the tumour: what is true for liver cancer Can I take Ayurveda alongside my liver cancer treatment? Can herbs interfere with liver cancer medicines? How to tell your oncologist about Ayurvedic medicine without being judged Spotting a fraudulent cancer treatment claim Why delay for alternative treatment costs the most in liver cancer What traditional medicine can reasonably offer in liver cancer A plain warning about liver tonics, with the Telugu words to share it

Cost, insurance and schemes

What does liver cancer treatment cost in India? What liver cancer treatment costs in Hyderabad, and why it varies What drives the cost of liver cancer treatment up or down The cost of diagnosing liver cancer: scans, markers and biopsy The cost of surgery vs ablation vs TACE vs Y-90 for liver cancer The monthly cost of liver cancer tablets and immunotherapy Liver transplant cost: what the bill includes and how to plan for it Does Aarogyasri cover liver cancer treatment, and what should you check? Aarogyasri and NTR Vaidya Seva: what they mean for liver cancer How to apply for Aarogyasri for liver cancer, step by step What Aarogyasri usually does not cover in liver cancer treatment Ayushman Bharat and liver cancer: what the card covers Does health insurance cover liver cancer treatment? Insurance and alcohol-related liver disease: the exclusion problem Insurance for liver cancer when you already had hepatitis B or C Insurance cover for a liver transplant: what a policy pays and what it leaves Does health insurance cover TACE and Y-90 for liver cancer? Cashless or reimbursement: which claim route suits liver cancer treatment? Chief Minister's Relief Fund and PM Relief Fund for liver cancer treatment Crowdfunding for liver cancer treatment or a liver transplant Paperwork to keep from day one of liver cancer care How to reduce liver cancer treatment costs without compromising care Travel and stay costs when you come to Hyderabad for liver cancer treatment How to talk to your oncologist about cost before liver cancer treatment starts

Liver cancer in Hyderabad

Liver cancer treatment in Hyderabad: what is available Where to get a liver cancer second opinion in Hyderabad Liver cancer surveillance clinics in Hyderabad: who needs one and what it does Where to get tested for hepatitis B and C in Hyderabad Free and subsidised hepatitis treatment in Telangana Hepatitis B vaccination in Hyderabad: where to go and what it costs Jeevandan: how registration for a liver transplant works in Telangana Liver transplant hospitals in Hyderabad: how to choose a centre Where TACE and Y-90 are available in Hyderabad Interventional radiology for liver cancer in Hyderabad Triple-phase CT and liver MRI in Hyderabad: cost, centres and getting it right Aarogyasri-empanelled centres for liver cancer in Hyderabad: how to check before you go Coming to Hyderabad for liver cancer treatment: how to plan the journey Accommodation near cancer hospitals in Hyderabad: affordable options for families Liver cancer care in Karimnagar, Nizamabad and Nalgonda Liver cancer care in Vizag, Srikakulam and Vizianagaram Liver cancer support groups in Hyderabad: what exists and how to find one Palliative and home care for liver cancer in Hyderabad Blood banks and platelet donors in Hyderabad: a guide for liver cancer families Nutrition and dietitian support for liver cancer in Hyderabad Alcohol de-addiction services in Hyderabad, for people with liver disease Liver cancer care in Telugu at CION, Hyderabad Why liver cancer is common in Telangana, and what is being done A liver health checklist for Telugu families
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